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How your first COVID-19 vaccination could 'hurt' subsequent boosters
Medical Xpress / Northwestern University / Cell Reports ^ | Feb. 15, 2023 | Tanushree Dangi et al

Posted on 02/16/2023 9:33:07 AM PST by ConservativeMind

The original vaccinations for COVID-19 induce potent antibodies that protect against SARS-CoV-2.

But a new study shows the antibodies generated by those prior vaccinations or infections can actually "hurt" the booster shots. That's because these antibodies rapidly "mop up" the booster from the body, before it has a chance to stimulate the cells from the immune system.

In a cohort of 85 people who had been vaccinated with Moderna or Pfizer-BioNTech vaccines, Northwestern scientists found that lower antibody levels before a booster were associated with a higher-fold increase in antibody levels after the booster.

"This suggests that pre-existing antibodies induced by prior vaccinations may negatively affect the level of responses induced by mRNA booster vaccines," Penaloza-MacMaster said.

"In other words, the antibody responses generated after prior vaccinations rapidly wipe out the vaccine during a subsequent booster shot, limiting the immune response that can be generated by the booster shot," Penaloza-MacMaster said. This was not caused simply by competition between antibodies and B cells for the vaccine antigen but seems to be the result of so-called "antibody effector mechanisms" that clear foreign substances from the body.

The new findings also suggest why increasing time between vaccinations is beneficial for the immune response, Penaloza-MacMaster said. "We showed in prior studies—as did other labs—that the longer the interval between vaccinations, the better the response. It's better to wait six months than two weeks before you boost, but the reasons for this were not clear."

Because the experiments in this paper show that high levels of antibodies induced by prior vaccines or infections can be detrimental for vaccine boosters, the scientists plan new experiments to administer drugs that transiently block antibody activity. They plan to give these drugs at the time of boosting to allow the vaccine to be sensed better by immune cells.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
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This may be why the boosters have some issues.
1 posted on 02/16/2023 9:33:07 AM PST by ConservativeMind
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To: ConservativeMind

I’ll never experience any problems


2 posted on 02/16/2023 9:34:59 AM PST by cyclotic
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To: ConservativeMind

85 people is not statistically significant.


3 posted on 02/16/2023 9:35:45 AM PST by fretzer
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To: ConservativeMind

But the justification for poorly tested ‘vaccines,’ which are actually gene therapy, has been exposed as false. Covid-19 was never worse than ‘normal’ influenza, it was just that patients were denied all treatments instead of using available medications.

Fauci and CO lied and said Covid-19 was ‘novel’ therefore none of us had any immunity to it. But that’s obviously not true. Many people never got Covid or had a mild case, because it was similar enough to other coronaviruses for them to have some immunity.

Many on FR have used HCQ or Ivermectin with great success. There have been treatment protocols available to the public (Dr. Zelenko, Dr. McCullough) since 2021 so there’s no need for a toxic shot that doesn’t work.


4 posted on 02/16/2023 9:37:46 AM PST by ransomnote (IN GOD WE TRUST)
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To: ConservativeMind

Not if you’ve never had the 1st one 😉


5 posted on 02/16/2023 9:37:54 AM PST by V_TWIN (America...so great even the people that hate it refuse to leave!)
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To: cyclotic

I’ll never experience any problems

Same here , never touched the stuff


6 posted on 02/16/2023 9:44:24 AM PST by butlerweave
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To: fretzer

Junk science.


7 posted on 02/16/2023 9:44:32 AM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: ConservativeMind
The original vaccinations for COVID-19 induce potent antibodies that protect against SARS-CoV-2.

Over the last 3 years, this assertion has been proven false.

8 posted on 02/16/2023 9:47:35 AM PST by MortMan (You better bring yours, when you come to take mine. - Creed Fisher)
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To: ConservativeMind

So “the vax is failing because of the vax.” Many of us could have told them that, though not in the circular way they’re trying to explain away their problems here.


9 posted on 02/16/2023 9:49:27 AM PST by noiseman (The only thing necessary for the triumph of evil is for good men to do nothing.)
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To: cyclotic

>> I’ll never experience any problems

Me neither... nothing in my system to “boost”! :-)


10 posted on 02/16/2023 9:52:03 AM PST by Nervous Tick (Truth is not hate speech.)
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To: cyclotic
I see...the first jab makes the 2nd, 3rd and 4th jabs impotent and harmless so they most certainly are not the cause of heart attacks and strokes in 24 year olds. Yeah that's the ticket!
11 posted on 02/16/2023 9:53:57 AM PST by suijuris (Once a man learns to see he finds himself alone in the world with nothing but folly.)
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To: ConservativeMind

Oops! Nope. Not buying one word. They knew. They can keep their clot shot.


12 posted on 02/16/2023 9:54:12 AM PST by bk1000 (Banned from Breitbart)
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To: ConservativeMind
The original vaccinations for COVID-19 induce potent antibodies that protect against SARS-CoV-2.

LOL...stopped reading, right there.

13 posted on 02/16/2023 9:55:22 AM PST by Jane Long (What we were told was a “conspiracy theory” in 2020 is now fact. 🙏🏻 Ps 33:12 )
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To: suijuris

ABT$™


14 posted on 02/16/2023 9:56:02 AM PST by Jane Long (What we were told was a “conspiracy theory” in 2020 is now fact. 🙏🏻 Ps 33:12 )
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

15 posted on 02/16/2023 10:00:38 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Blocking antibodies to the spike…so you can get injected with more spikes…sounds like junk science to me.

But then, I am not a Pfizer stockholder


16 posted on 02/16/2023 10:01:30 AM PST by silverleaf (“Freedom ultimately means the right of other people to do things that you disagree with”. T. Sowell )
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To: ConservativeMind

The experimental mRNA gene therapy is not safe or effective.


17 posted on 02/16/2023 10:05:33 AM PST by bray (Order at TheRepublicofTexas.store)
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To: ConservativeMind
"...[original vax] antibodies rapidly "mop up" the booster from the body, before it has a chance to stimulate the cells from the immune system."

Simple solution -- monthly boosters? Or should it be bi-weekly?

18 posted on 02/16/2023 10:11:25 AM PST by ProtectOurFreedom (Once you get people to believe that a plural pronoun is singular, they'll believe anything - nicollo)
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To: bray
The experimental mRNA gene therapy is not safe or effective.

It's safe for the ones mandating it. As far as effectiveness, that depends on what outcome one wants.

19 posted on 02/16/2023 10:21:58 AM PST by BipolarBob (The rumor has not been confirmed until the FBI officially denies it.)
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To: V_TWIN

To me this reads like a faint attempt to cover for the disaster called Covid-19 Vaccines. You can almost hear the panic in the back offices.


20 posted on 02/16/2023 10:28:45 AM PST by WVNan
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