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The significant impact of ED drugs on men's cardiac health
Medical Xpress / Huntington Medical Research Institutes / The Journal of Sexual Medicine ^ | Jan. 31, 2023 | Robert A Kloner et al

Posted on 02/03/2023 2:50:49 PM PST by ConservativeMind

A comprehensive research study manuscript examining the impact of erectile dysfunction drugs on major adverse cardiovascular events (MACE) and mortality has been published.

This study marks a significant medical milestone, as it's the first time the association between the use of PDE-5i drugs and cardiovascular health has been explored in a large population of relatively low-risk men with ED in the United States.

In this study, scientists analyzed health records of more than 70,000 men with ED. According to the findings of this large-population study, men who took Viagra, Cialis, Levitra and other drugs of the same class for erectile dysfunction (ED) experienced lower rates of major adverse cardiovascular events (MACE) including lower rates of heart failure and death due to heart disease compared to other men with ED not exposed to these drugs.

Among the men who took PDE-5i medications for ED compared to men with ED who did not take these drugs, Kloner's study identified:

39% lower rate of death due to heart disease,

22% lower rate of unstable angina,

17% lower rate of heart failure,

15% lower rate in the need for revascularization procedures such as angioplasty, stenting and bypass surgery,

13% lower rate of MACE, and

25% lower rate of death due to any cause.

Principal investigator Robert A. Kloner, MD, Ph.D. drew anonymized patient records from a large U.S. commercial and Medicare insurance claims database. The study examined records over approximately 14 years.

Due to the retrospective nature of the study, the research team cannot say anything about the cause of the benefit, only that there was an association between the exposure to PDE 5 inhibitors and lower rates of cardiovascular events. These results raise the possibility that the PDE5 inhibitors may have cardioprotective properties.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: adverse; contraindication; ed; tadalafil; takethosedrugs; viagra
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To: ConservativeMind

I had suffered from neuropathy in both my feet, and then experienced drop foot in my left foot.

I ask my VA Doc (yes VA doc) to prescribe daily Cialis for the neuropathy suggesting to him that if it opened up the veins in one part of the body it should work in the feet too. He agreed, and wrote a prescription. (It had to be outside the VA since the VA pharmacy couldn’t provide it)

My drop foot is vastly improved at this point and I can walk normally again. Huge improvement...


21 posted on 02/03/2023 3:42:04 PM PST by babygene (Make America Great Again)
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To: ConservativeMind

Cialis,

“Il fait le bonheur!”


22 posted on 02/03/2023 3:46:06 PM PST by tsomer
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To: cpdiii

Correctomundo.


23 posted on 02/03/2023 3:54:55 PM PST by Bonemaker (invictus maneo)
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To: ConservativeMind

They need special locking caskets or they stay open and are difficult to close.


24 posted on 02/03/2023 4:00:16 PM PST by George J. Jetso
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To: Timothy

Does cialis give you that shitty after feeling like viagra?


25 posted on 02/03/2023 4:00:49 PM PST by Bonemaker (invictus maneo)
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To: Bonemaker

‘Does cialis give you that shitty after feeling...’
Anal sex has a price.


26 posted on 02/03/2023 4:18:57 PM PST by donaldwin2024
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To: donaldwin2024

I wouldn’t know and I don’t want to know!😐


27 posted on 02/03/2023 4:23:04 PM PST by Bonemaker (invictus maneo)
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To: ConservativeMind

28 posted on 02/03/2023 5:00:34 PM PST by CapnJack ( )
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To: ConservativeMind

.


29 posted on 02/03/2023 5:21:52 PM PST by sauropod (“If they don’t believe our lies, well, that’s just conspiracy theorist stuff, there.”)
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To: ConservativeMind

That sort of result is really hard to determine.


30 posted on 02/03/2023 5:28:40 PM PST by Billthedrill
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To: ConservativeMind

I heard that this type of drug was first intended to treat/prevent heart disease in men.


31 posted on 02/03/2023 6:46:28 PM PST by Flaming Conservative ((Pray without ceasing))
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To: ConservativeMind

They can have my Viagra when they pry it from my cold, dead...err...never mind.


32 posted on 02/03/2023 7:00:43 PM PST by moovova ("The NEXT election is the most important election of our lifetimes!“ LOL...)
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To: sauropod

“experienced lower rates of major adverse cardiovascular events (MACE) including lower rates of heart failure and death due to heart disease compared to other men with ED not exposed to these drugs.”

Exercise gives lower rates of heart failure?


33 posted on 02/04/2023 2:48:24 PM PST by Does so (What distinguishes today's Russian aggression from that of the USSR?)
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To: Does so

Makes sense to me.


34 posted on 02/04/2023 4:31:39 PM PST by sauropod (“If they don’t believe our lies, well, that’s just conspiracy theorist stuff, there.”)
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