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Drugs to prevent anxiety, stress reactions and inflammation found to reduce risk of metastases after tumor surgery (Propranolol & etodolac provided 1/4 the metastasis of placebo)
Medical Xpress / Tel Aviv University / European Journal of Surgical Oncology / Nature Reviews Cancer ^ | Dec. 6, 2022 | Itay Ricon-Becker et al / Anabel Eckerling et al

Posted on 12/07/2022 9:50:35 PM PST by ConservativeMind

A short, simple and safe drug treatment developed at Tel Aviv University reduced the risk of the spread of cancer metastases after surgery to remove the primary tumor.

The research was led by Prof. Shamgar Ben-Eliyahu.

The risk of metastases after tumor removal is estimated at 35% among colon cancer patients.

Prof. Ben-Eliyahu explains, "The stress and inflammation reactions and anxiety of cancer recurring—all have an adverse effect on the body's ability to fight metastatic processes."

"The good news is that we know how to treat both stress and inflammation using off-the-shelf medications."

The researchers gave 34 colon cancer patients two safe drugs that are available in every pharmacy: propranolol (Darlin), used to lower blood pressure and reduce anxiety, and etodolac (Etopan), used to prevent pain and inflammation.

Sixteen randomly chosen patients took the medication for 20 days—from five days before to two weeks after surgery. The other 18 patients received placebo drugs (control group). Five years later, nine of the 18 patients who received the placebo (50%) developed cancer metastases, compared to two of the 16 patients who took Darlin and Etofen (12.5%).

Prof. Ben-Eliyahu adds, "Although at five years after the operation, the statistical significance is clear. Our treatment reduced markers of metastasis in the tumor tissue, and reduced the chances of cancer recurrence. This is a short, cheap drug treatment with no significant side effects. We deliberately sought the safest and cheapest drugs capable of lowering the body's stress-inflammatory response to surgery, in order to save lives."

"It sounds too good to be true, but similar results in breast cancer tissue were obtained in a study we conducted in 2017. The effects are statistically significant, meaning that they are not accidental."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: breastcancer; cancer; coloncancer; metastasis; tcoyh
This worked with both breast cancer and colon cancer, but the studies were small.

One costs about $10 and the other about $25, on GoodRX.

1 posted on 12/07/2022 9:50:35 PM PST by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 12/07/2022 9:51:20 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

The drugs were only taken for 20 days!

I forgot to add that in the first post.


3 posted on 12/07/2022 9:55:04 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I will not believe anything from the medical community again.


4 posted on 12/07/2022 10:35:17 PM PST by FreeperCell
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To: ConservativeMind

Try Singlecare, they beat GoodRx often.


5 posted on 12/08/2022 12:34:51 AM PST by krogers58
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To: ConservativeMind

Interesting research but people needing drugs for stress and anxiety can’t handle life to begin with.


6 posted on 12/08/2022 4:13:43 AM PST by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: ConservativeMind

When cancer’s cured we’ll have Israeli doctors to thank...


7 posted on 12/08/2022 4:20:13 AM PST by GOPJ (Has Biden had dinner with an "anti-evangelical"? Will Schumer condemn him if he has?)
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