Posted on 12/01/2022 3:55:20 PM PST by ConservativeMind
Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease.
Osteoarthritis is the most common form of arthritis, affecting 32.5 million adults in the U.S. Knee osteoarthritis is a chronic, degenerative and progressive condition with an estimated incidence of 800,000 patients each year. More than 10% of patients with knee osteoarthritis seek noninvasive treatment for pain relief through corticosteroid or hyaluronic acid injections.
In the first study, MRI was performed on all patients at the time of the injection and two years before and after. The MRI scans were assessed using whole-organ magnetic resonance imaging score (WORMS), a grading system for knee osteoarthritis that focuses on the meniscus, bone marrow lesions, cartilage, joint effusion and ligaments.
Statistical analysis showed that corticosteroid knee injections were significantly associated with the overall progression of osteoarthritis in the knee, specifically in the lateral meniscus, lateral cartilage and medial cartilage.
Hyaluronic acid knee injections were not significantly associated with the progression of osteoarthritis in the knee. Compared to the control group, the group who received hyaluronic injections showed a decreased progression of osteoarthritis, specifically in bone marrow lesions.
In the second study, researchers conducted a case-control study comparing the radiographic progression of osteoarthritis in patients who received injections of corticosteroids and hyaluronic acid.
Compared to patients who received an injection of hyaluronic acid or no treatment at all, patients injected with corticosteroids had significantly more osteoarthritis progression, including medial joint space narrowing, a hallmark of the disease.
"Even though imaging findings for all patients were similar at baseline, the imaging hallmarks of osteoarthritis were worse two years later in patients who received corticosteroid injections compared to patients who received hyaluronic acid injections or no treatment at all," Darbandi said.
(Excerpt) Read more at medicalxpress.com ...
Steroids in weight lifters has also been know to cause chinese wiwi syndrome
You might add cataracts to the list of side effects.
I don’t think that’s correct...
I am trying to avoid the injection and concentrate on the histamine part of it
https://med.stanford.edu/news/all-news/2019/05/mast-cells-crucial-to-causing-osteoarthritis.html
This has been known for years.
My knees were pretty bad 20 years ago and I was on a cane wondering about wheel chairs when I got turned on to Glucosamine-and-Chondroitin. That fixed me right up. Since then I have graduated to Curcumin and Ginger which I get in bulk and put on my food. I have no signs of arthritis now except in one thumb which doesn’t seem amenable to anything.
One of our products was in clinical trials, a wound product. I told them not to use the product on people taking steroids. They didn’t listen and we have to sponsor another trial with steroids as contraindicated.
I’m just the materials engineer.
Have you tried boron?
Steroids decrease your inflammatory response that repairs. 12 hour shifts in a hospital are getting to me…. But steroids were never a choice.
Next I am trying my resveratol, carlsons fish oil and eggshell membrane.
Have you tried boron?
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