Posted on 10/28/2022 10:02:25 AM PDT by ConservativeMind
Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research.
"Most people know about the painful rash associated with shingles, but they may not know that the risk of stroke is elevated for a year after infection," said Andrew Bubak, Ph.D.
Researchers have found that shingles can also increase the risk of stroke especially for those under age 40 where the shingles vaccine is not typically recommended.
The risk is greatest in people with the rashes on their faces, perhaps due to the proximity to the brain.
To better understand, Bubak and his team began looking more closely at exosomes.
"Exosomes carry pathogenic cargo that can cause thrombosis and inflammation distant from site of actual infection," Bubak said. "That could ultimately lead to a stroke in patients."
Researchers collected plasma samples from 13 patients with shingles and 10 without taken at time of infection and at 3-month follow-ups and exosomes were extracted from the plasma.
The researchers found prothrombotic exosomes which could cause blood clots in those with the infection. They also discovered proinflammatory exosomes that also pose risks for stroke at the 3-month follow-up.
Bubak said the findings suggest that in a subset of people with shingles, the virus may not return to latency or the circulating exosomes that induce a prolonged prothrombotic state may persist even after therapy is done and the rash is gone. He said using antiviral agents longer with the addition of antiplatelet and anti-inflammatory agents could help.
Most physicians are unaware of the connection between shingles and stroke.
"But it's really important and so easily mitigated," Bubak said. "Send them home with antiplatelet agents."
(Excerpt) Read more at medicalxpress.com ...
I am 65 and had shingrix (2 shots, a few months apart), about 2 years ago.
Partly due to my younger brother DID have shingles, and it was awful. We all had chicken pox, and my son (now 38) had VERY mild chicken pox, but had it like 3 times of just a handful of blisters each time. These two issues made me think it would be good to get the vaccine.
Also my former father-in-law had a BAD case of shingles, when he was in his later 60s, and suffered a great deal of pain, was unable to get out or do much for several months.
I had no reaction issues to the shots, but a co-worker of mine at the time, did have some swelling in her arm, as well as general nausea/malaise feeling for a couple days after getting it.
Sorry, your post confuses me.
Yep
“interesting that it can lead to stroke”
Yeah, that’s certainly news to me, and a little scary to be sure.
when I saw my Dr. to verify what I hoped was not the case but turned out to be he told me shingles attacks a particular nerve group.
In my case it was from the middle of my chest, around under my left arm all the way to my backbone.
That was fall 2019 to February 2020.
Apparently the nerve damage can be permanent......I have places the virus attacked where I still have numbness......and I guess always will.
“but they may not know that the risk of stroke is elevated for a year after infection,” said Andrew Bubak, Ph.D.
A year after “INFECTION”? Shingles are OUTBREAKS. You initially get infected with Chicken Pox (Herpes Zoster) most likely in your youth. So I am not quite sure how you “VACCINATE” against something you already have. The article explains this better further in. I had a shingles outbreak in college but I was infected in Kindergarten. To me the headline reads as a fear mongering, inaccurate sales pitch from the industrial medical complex.
You are correct, but it’s possible the interviewed doctor did that to put it into more conventional terms, but it is wrong.
Technically Shingles is a new type of eruption from the same virus.
“Fauci Juice.”
Me likee!!! Gonna steal that.....wait......I just did!!! :0)
People are getting shingles after the covid fake vaxes.
Hmmm....it’s been four years since shingles on my face put me in the hospital. No strokes. Since then I’ve gotten the Shingrix vaccine. The day after the second shot I slept for 15 hours...felt like I was in the hospital again.
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