Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Aspirin as effective as standard blood thinner to prevent life-threatening blood clots and death after fracture surgery
MedicL Xpress / Univ. of Maryland Schl. of Med. / Orthopedic Trauma Association (OTA) annual mtg. ^ | Oct. 14, 2022 | Robert V. O'Toole, MD

Posted on 10/14/2022 5:27:02 PM PDT by ConservativeMind

Patients who have surgery to repair bone fractures typically receive a type of injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots, but a new clinical trial found that over-the-counter aspirin is just as effective.

The multi-center randomized clinical trial of more than 12,000 patients at 21 trauma centers is the largest-ever trial in orthopedic trauma patients.

Said Robert V. O'Toole, MD: "Orthopedic trauma patients are commonly prescribed the blood thinner low-molecular-weight heparin to prevent blood clots for weeks following surgery. Not only does the medication need to be injected, it can also be quite expensive compared to aspirin."

Blood clots cause as many as 100,000 deaths in the U.S. each year. Patients who experience fractures that require surgery—an estimated 1 million people in the U.S. annually—are at increased risk of developing blood clots in the veins, including a fatal pulmonary embolism, which is a clot in the lung. Current guidelines recommend prescribing low-molecular-weight heparin (enoxaparin), although research in total joint replacement surgery suggested a potential benefit of aspirin as a less-expensive, widely available option.

The study enrolled 12,211 patients with leg or arm fractures that necessitated surgery or pelvic fractures regardless of the specific treatment. Half were randomly assigned to receive 30 mg of injectable low-molecular-weight heparin twice daily. The other half received 81 mg of aspirin twice daily. The follow-up period after surgery was 90 days.

The main finding of the study was that aspirin was "noninferior," or no worse, than low-molecular-weight heparin in preventing death from any cause—47 patients in the aspirin group died compared with 45 patients in the heparin group. Secondary outcomes noted no differences in non-fatal pulmonary embolism. The incidence of bleeding complications and all other safety outcomes was similar in both groups.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: aspirin; bloodthinner; surgery
There were slightly fewer smaller, lower leg blood clots in the heparin group over the aspirin group, but otherwise the results were the same.

I’m surprised two baby aspirins equal two injected doses of heparin.

1 posted on 10/14/2022 5:27:02 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: ConservativeMind

I remember having to give myself lovenox shots.


2 posted on 10/14/2022 5:27:56 PM PDT by lilypad
[ Post Reply | Private Reply | To 1 | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

3 posted on 10/14/2022 5:28:02 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Maybe, but not nearly as profitable.


4 posted on 10/14/2022 5:34:11 PM PDT by glorgau
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

So maybe that will help with after-jab treatment.


5 posted on 10/14/2022 5:34:17 PM PDT by \/\/ayne (I regret that I have but one subscription cancellation notice to give to my local newspaper)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

I’ve been taking low dose for at least 10 years and I ain’t dead yet. As far as I know.


6 posted on 10/14/2022 5:36:16 PM PDT by Theophilous Meatyard III (I)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Does it work for the Pfizer vaccine?


7 posted on 10/14/2022 5:48:22 PM PDT by dljordan
[ Post Reply | Private Reply | To 1 | View Replies]

To: Theophilous Meatyard III

Some here would say your account is anecdotal. And/or that “you’re not a doctor”.

:) /doctor karens


8 posted on 10/14/2022 5:48:35 PM PDT by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
[ Post Reply | Private Reply | To 6 | View Replies]

To: ConservativeMind

What a minute! Recently the experts were telling us that aspirin was dangerous and not recommended at all. Remember those stories telling people not to take aspirin to prevent blood clots after vaccinations?


9 posted on 10/14/2022 5:53:58 PM PDT by CFW
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Efficacious, but inexpensive? That will never work for the folks at big Pharma...
If it works, it must be prohibitively expensive (/sarc).


10 posted on 10/14/2022 6:00:49 PM PDT by PubliusMM (RKBA; a matter of fact, not opinion. The Dhimmicraps are ALL Traitors. All of them.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

In March of this year my wife had a hip replacement.

No heavy duty blood thinners.

Here is what she received and the doseage.

Aspirin EC 81 Mg Tablet
Instructions:
Take 1 tablet by mouth 2 times a day. After 30 days, resume prior regimen.

After 30 days, she is back on her once a day, 1 Aspirin tab regimen.


11 posted on 10/14/2022 6:25:31 PM PDT by Grampa Dave ( Anyone, who can make you believe in absurdities, can make you commit atrocities!!" ~ (Voltaire)!, )
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

At a psychiatric lecture I attended, the panel presented that the same neuropathways for physical pain were also for emotional pain.

Sad, take a Tylenol.


12 posted on 10/14/2022 6:43:33 PM PDT by tired&retired (Blessings )
[ Post Reply | Private Reply | To 1 | View Replies]

To: tired&retired

Interesting.


13 posted on 10/14/2022 9:13:11 PM PDT by MayflowerMadam (It amazes me how much "exercise" and "extra fries" sound alike.)
[ Post Reply | Private Reply | To 12 | View Replies]

To: MayflowerMadam

“When people feel emotional pain, the same areas of the brain get activated as when people feel physical pain: the anterior insula and the anterior cingulate cortex.

In one study, these regions were activated when people experienced an experimental social rejection from peers.

In another more real-life study, the same regions were activated when people who had recently broken up with romantic partners viewed pictures of the former partner.”

https://www.psychologytoday.com/us/blog/body-sense/201204/emotional-and-physical-pain-activate-similar-brain-regions


14 posted on 10/14/2022 11:23:02 PM PDT by tired&retired (Blessings )
[ Post Reply | Private Reply | To 13 | View Replies]

To: PubliusMM

The problem with the cynic’s views of “Big Pharma” and “doctors” are that Heparin is never used for long, nor is Lovenox.

Aspirin, esp. the baby kind, has been recommended for decades now as anti-coag for any of us at risk on a daily basis.


15 posted on 10/15/2022 8:15:37 AM PDT by the OlLine Rebel (Common sense is an uncommon virtue./Federal-run medical care is as good as state-run DMV.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: \/\/ayne
So maybe that will help with after-jab treatment.

The jab clots have NO iron and are NOT blood clots, they are foreign material clogging blood vessels.

A few embalmers have said a fairly large % of vaxxxxxxxed deaths have significant blood blockage...

RUMBLE VIDEO HORROR: Embalmer Finding Fibrous Clots In Vaxxed Corpses; Big Tech, Big Pharma, & The Government Collude To COVER UP Jab Safety Issues

16 posted on 10/16/2022 2:02:38 PM PDT by politicianslie (Those who got vaxxed need to update their wills. You are a guinea pig in a dangerous drug trial.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: politicianslie

Dear God in Heaven


17 posted on 10/16/2022 2:14:10 PM PDT by combat_boots ( )
[ Post Reply | Private Reply | To 16 | View Replies]

To: politicianslie

Great so somebody has to invent a fibroid dissolver.


18 posted on 10/17/2022 8:58:33 AM PDT by \/\/ayne (I regret that I have but one subscription cancellation notice to give to my local newspaper)
[ Post Reply | Private Reply | To 16 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson