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Combination of poor gait and weak hand grip could be early indicators of dementia
Medical Xpress / Monash Univ. / Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring ^ | Oct. 4, 2022 | Suzanne G. Orchard et al

Posted on 10/04/2022 8:57:28 PM PDT by ConservativeMind

Walking speed and grip strength could be early indicators of dementia before the onset of noticeable symptoms, a study reveals.

Researchers found slow walking speed combined with weak hand grip was a stronger predictor of cognitive decline and dementia in older adults than either measure alone.

The study of data from more than 18,000 initially healthy adults, mostly aged 70 and older in the ASPREE trial, revealed that a combined poor gait speed and grip strength was linked to a 79% increased risk of dementia and a 43% increased risk of cognitive decline.

Over time, the risk for dementia or cognitive decline was shown to be highest when gait and grip declined simultaneously over the study period of nearly 5 years, with an 89% increased risk of dementia and 55% increased risk of cognitive decline.

Dr. Suzanne Orchard said the research showed an important link between age-related cognitive and physical decline.

Dr. Orchard said simple grip strength and gait speed assessments could be adopted by GPs and other health care providers to help identify dementia risk early and establish treatment pathways to improve patient outcomes.

The study was conducted using data from the landmark ASPREE—ASPirin in Reducing Events in the Elderly—clinical trial. The multi-center trial, exploring low dose aspirin and disability-free survival in older adults, mostly aged over 70.

Participants' grip strength and gait speed were measured upon entry to ASPREE and repeated during an average of 4.7 years.

Gait speed was timed walking at normal pace over a distance of three meters, while grip strength was assessed using a hand-held device to measure force. Researchers then compared these physical benchmarks against participants' cognition, measured using assessments that examine functions such as memory and processing speed.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: deamentia; hand; handstrength; walking; walkingspeed
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Interestingly, in other studies, GlyNAC reversed both grip and gait issues in 70-80 year olds, causing them to have a standard walking gait faster than the 30 year old controls, after 24 weeks. Those studies did use around 7 grams each of glycine and NAC, spread throughout the day.

This does not have to be a strict downward path for us. Yes, we eventually die, but we can postpone that and greatly improve our health, when it otherwise seemed impossible.

Don’t give up until you have to. Live your life to glorify God.

1 posted on 10/04/2022 8:57:28 PM PDT by ConservativeMind
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To: ConservativeMind

“7 grams each of glycine and NAC”

Sounds like a lot.


2 posted on 10/04/2022 9:00:34 PM PDT by Paladin2
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

3 posted on 10/04/2022 9:00:55 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Paladin2
That would be, but 1,200 mg (600 mg of each, twice a day) of each a day is what Nestle suggests with their GlyNAC product, for the general population.

My wife and I have been taking 1,800 mg of each for nearly three months, and are doing well.

4 posted on 10/04/2022 9:03:30 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Interesting, Nitro-Glycine is what they put in my treatment for poor blood circulation. I still have all these issues even with all this stuff....I am doomed.


5 posted on 10/04/2022 9:36:05 PM PDT by dila813
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To: dila813

My theory is still that we need to have “Scrubbing Bubbles” invented to keep the vascular system open.


6 posted on 10/04/2022 9:47:15 PM PDT by Paladin2
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To: ConservativeMind

“Gait and grip declined simultaneously.” Meaningless. My two family members with dementia for more than ten years have smooth gait and strong grips. FYI: Avoiding dementia includes avoiding large quantities of sodium.


7 posted on 10/04/2022 9:49:46 PM PDT by Falconspeed ("Keep your fears to yourself, but share your courage with others." Robert Louis Stevenson.)
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To: Falconspeed

Sodium, why is that?


8 posted on 10/04/2022 9:54:47 PM PDT by GnuThere
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To: Paladin2

My grandpa used to swear by Kentucky bourbon as Antifreeze for the blood but he got cancer from it but he was sharp as a tac to the day he died


9 posted on 10/04/2022 9:57:19 PM PDT by dila813
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To: dila813

“he was sharp as a tac to the day he died”

There are worse ways to go.


10 posted on 10/04/2022 10:00:36 PM PDT by Paladin2
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To: ConservativeMind

“My wife and I have been taking 1,800 mg of each for nearly three months, and are doing well.”

I am taking those doses as well (approximately), but did not have a problem with deficient grip strength or slow gait and have not noticed any differences. Still waiting for that waist size reduction...


11 posted on 10/04/2022 10:07:53 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: Paladin2; ConservativeMind

Yes, 7,000 mg each sounds like way too much.

I still take NAC on my COVID regimen and haven’t had any respiratory infections in 2-1/2 years since starting. I’m taking 1,000 mg NAC daily.


12 posted on 10/04/2022 10:41:02 PM PDT by ProtectOurFreedom (“I used to be nothing but a Deplorable Clinger, but I've been promoted to Brigadier Ultra-MAGA”)
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To: ConservativeMind

“Gait speed was timed walking at normal pace over a distance of three meters,”

TEN feet? Unbelievably short.

My wife and I are pretty good hikers at 71 years. We hiked in Glacier National Park last week and passed almost everybody our age and passed a fair number of people in their 20s and 30s on a 8 mile hike, 800 feet elevation gain (in a one mile distance), and 4,000 feet elevation. We used to pass everybody, but still, I’m happy with what we can still do. So this study is heartening.


13 posted on 10/04/2022 10:51:32 PM PDT by ProtectOurFreedom (“I used to be nothing but a Deplorable Clinger, but I've been promoted to Brigadier Ultra-MAGA”)
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To: ConservativeMind

14 posted on 10/05/2022 1:12:42 AM PDT by LibWhacker
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To: ConservativeMind

As an active golfer in a retirement community, it is easy to spot people suffering from physical and mental decline by the way they walk. I almost never get irritated by how slow they are because there but for the grace of God go I. Also, golfers, like me, with weak grips slice the ball. I have to remind myself to maintain a grip on the club.


15 posted on 10/05/2022 1:27:12 AM PDT by DeplorablePaul ("..)
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To: LibWhacker

lol


16 posted on 10/05/2022 1:51:16 AM PDT by Gene Eric (Don't be a statist!)
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To: Falconspeed

Did you get the last part from Dr. Oz or Dr. Mercola?


17 posted on 10/05/2022 3:33:43 AM PDT by EEGator
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To: ConservativeMind

Bkmk


18 posted on 10/05/2022 4:15:13 AM PDT by rockabyebaby (THE BEST IS YET TO COME - (PRESIDENT DONALD J. TRUMP))
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To: ConservativeMind

Voting for democrats is also another early indicator of dementia.


19 posted on 10/05/2022 4:28:00 AM PDT by FlingWingFlyer (You can vote your way into socialism/communism but you need guns to shoot your way out.)
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To: ConservativeMind

I don’t doubt the connection between gait and early decline, as I think we see it all the time.

But I think I’d be challenged to walk at my “standard” pace on command, so I’m not sure how accurately they measure it.


20 posted on 10/05/2022 4:31:09 AM PDT by 9YearLurker
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