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Data on cancer risk from hormone therapy 'reassuring,' menopause experts say (Generally okay until 60)
Medical Xpress / University of Virginia / Menopause ^ | August 24, 2022 | JoAnn V. Pinkerton et al

Posted on 08/24/2022 9:50:40 PM PDT by ConservativeMind

A new paper and other recent evidence offer important reassurances about the risk of breast cancer from hormone therapy to treat menopause symptoms.

Hormone therapy can help relieve menopause symptoms such as hot flashes, night sweats, sleep disturbances, vaginal issues, sexual problems and loss of bone density.

The new review provides much-needed clarity, according to JoAnn V. Pinkerton, MD, and Carolyn S. Wilson, MD.

"When prescribed to women after hysterectomy, estrogen therapy used alone at menopause did not increase the risk of invasive breast cancer. Longer durations of estrogen therapy use may increase risk. For women with an intact uterus who need combined estrogen and progestogen, the risk of breast cancer increased slightly and persisted after discontinuation," said Pinkerton. "Women and their healthcare providers should feel reassured about the safety of hormone therapy when used at menopause."

Their results, Pinkerton and her co-authors say in the accompanying editorial, "make a strong case" that hormone therapy taken at menopause does not increase the risk of invasive breast cancer for women who have received a hysterectomy.

The editorial notes that estrogen combined with progesterone increases breast cancer risk for women who have not undergone a hysterectomy, especially when used long-term. However, the authors point to another study indicating that the increased risk did not translate into a higher risk of death.

Further, the authors note that not all progestogens—medications that protect against estrogen-stimulated cancer—carry equal breast cancer risk. It appears that estrogen combined with micronized progesterone and dydrogesterone does not increase breast-cancer risk to the same degree as other combinations.

"Let's replace fear with knowledge," Pinkerton said. "Most healthy women under age 60 or within 10 years of having their last period and having bothersome symptoms can take hormone therapy without fear at menopause if taking estrogen alone or combined with progesterone."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
A potentially helpful option for women.
1 posted on 08/24/2022 9:50:40 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20% fewer pings) or “Everything” list.

2 posted on 08/24/2022 9:51:10 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I know a 75 year old woman who is stupidly still on the pill…. Because it makes her “feel” better


3 posted on 08/24/2022 10:05:02 PM PDT by Nifster (I see puppy dogs in the clouds )
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To: Nifster

A 75 she’s chosen for quality of life rather than longevity.


4 posted on 08/24/2022 10:55:51 PM PDT by caww (O death, when you seized my Lord, you lost your grip on me......Augustine)
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To: caww

A 75 she’s chosen for quality of life rather than longevity.


My doctor said the same thing.

Why aren’t they telling transgenders to stay off the hormones and massive amount of doses of estrogen that males like Bruce Jenner and Blair White are taking?


5 posted on 08/24/2022 11:26:41 PM PDT by sumuam
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To: sumuam

Yes, the trans people are unfortunately creating shortages of estrogen for post-menopausal women.


6 posted on 08/25/2022 12:44:34 AM PDT by olivia3boys
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To: ConservativeMind

These are the same people who accuse dairy farmers of adding hormones to the milk and speeding up puberty…as they promote hormone therapy and promote sex between underage.


7 posted on 08/25/2022 12:58:00 AM PDT by Hypo2
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To: olivia3boys

Yes, the trans people are unfortunately creating shortages of estrogen for post-menopausal women.


Exactly, what I thought of as well. They plan to make everyone miserable who is normal.


8 posted on 08/25/2022 1:16:56 AM PDT by sumuam
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To: caww

Not really. She fools herself. She claims without them she would still get hot flashes. Just not true.

I’m all for chowing quality of life She is just nuts


9 posted on 08/25/2022 1:31:26 AM PDT by Nifster (I see puppy dogs in the clouds )
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To: ConservativeMind
Interesting. I was skeptical, because I know people who formed masses while using HRT that vanished when they stopped.

However NIH studies seem to indicate an inverse relationship to cancer risk when the patient uses HRT. Perhaps those incidents were not related to HRT at all. I know the folks I speak of will not consider HRT again. Perhaps I should ask them to simply consider it a miracle, I've seen a few so this is plausible.

In summary, this study shows a consistent protective effect of ever use of HRT against colorectal and liver cancers and an increased risk for gallbladder, breast, endometrium and bladder cancers. In addition to the results already published from observational studies and U.S. clinical trials2, 40, 42 this data from a southern European population could be of help in the risk-benefit assessment of HRT among postmenopausal women.

Hormone replacement therapy and cancer risk: A systematic analysis from a network of case-control studies

10 posted on 08/25/2022 4:14:09 AM PDT by Caipirabob (Communists...Socialists...Fascists & AntiFa...Democrats...Traitors... Who can tell the difference?)
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To: ConservativeMind

What KIND of hormones? Pills, BioIdentical creams? Big difference.


11 posted on 08/25/2022 6:23:07 AM PDT by goodnesswins (The Chinese are teaching calculus to their 3rd graders while ours are trying to pick a pronoun.)
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To: Nifster

“the pill” - you mean birth-control pill?

If her doctor allows it and she thinks it helps, so be it.

May not be exactly the same as HRT pills but pretty close.


12 posted on 08/25/2022 6:28:20 AM PDT by the OlLine Rebel (Common sense is an uncommon virtue./Federal-run medical care is as good as state-run DMV.)
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To: goodnesswins

“It appears that estrogen combined with micronized progesterone and dydrogesterone does not increase breast-cancer risk to the same degree as other combinations.”


13 posted on 08/25/2022 6:28:54 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Nifster
Just not true.

Au contraire. Per the Cleveland Clinic...

"Will my hot flashes stop after menopause? Some people still experience hot flashes after menopause. Postmenopausal hot flashes are caused by decreased estrogen levels. It is not uncommon to experience a random hot flash for years after menopause. If your hot flashes are bothersome or intensify, speak with your healthcare provider to rule out other causes."

14 posted on 08/25/2022 6:34:48 AM PDT by mewzilla (We need to repeal RCV wherever it's in use and go back to dumb voting machines.)
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To: ConservativeMind

Try DHEA instead. It stimulates the lost hormone detection and generation processes in natural proportions.


15 posted on 08/25/2022 7:10:31 AM PDT by nagant
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To: ConservativeMind

What KIND of estrogen? It matters.


16 posted on 08/25/2022 7:34:13 AM PDT by goodnesswins (The Chinese are teaching calculus to their 3rd graders while ours are trying to pick a pronoun.)
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To: ConservativeMind; All

Types of Estrogens...
https://www.news-medical.net/health/Estrogen-Types.aspx

Horse estrogen is NOT good for women


17 posted on 08/25/2022 7:43:38 AM PDT by goodnesswins (The Chinese are teaching calculus to their 3rd graders while ours are trying to pick a pronoun.)
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To: Nifster

She’s right....woman can and do indeed get hotflashes into their 70’s. Not everyone bu don’t discount her statement. I know from first hand expereince.


18 posted on 08/25/2022 8:30:56 AM PDT by caww (O death, when you seized my Lord, you lost your grip on me......Augustine)
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To: sumuam
Yes indeed. That question was put before me when i began experiencing menopause in my mid 30’s. Horrendous hot-flashes enough to have perspiration rolling down my face. This happened during a critical business meeting where the client thought i was on drugs or something!

So i went on hormone therapy in my 30’s and never regretted it.

19 posted on 08/25/2022 8:35:13 AM PDT by caww (O death, when you seized my Lord, you lost your grip on me......Augustine)
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To: caww

But she has no idea if that’s true for her or not. She’s been taking these pills since she was 42


20 posted on 08/25/2022 1:57:34 PM PDT by Nifster (I see puppy dogs in the clouds )
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