Posted on 08/20/2022 8:39:32 PM PDT by ConservativeMind
A randomized, double blind human clinical trial reveals that supplementation with GlyNAC—a combination of glycine and N-acetylcysteine—improves many age-associated defects in older humans and powerfully promotes healthy aging. This is relevant because until now, there have been no solutions toward improving many of these age-related declines in people.
The study shows that older humans taking GlyNAC for 16-weeks improved many characteristic defects of aging. This includes oxidative stress, glutathione deficiency and multiple aging hallmarks affecting mitochondrial dysfunction, mitophagy, inflammation, insulin resistance, endothelial dysfunction, genomic damage, stem cell fatigue and cellular senescence. These were associated with improvements in muscle strength, gait speed, exercise capacity, waist circumference and blood pressure.
"This is the first randomized clinical trial of GlyNAC supplementation in older humans, and it found that a wide variety of age-associated abnormalities improved in older adults supplemented with GlyNAC, while no improvements were seen in those receiving placebo," said author Dr. Rajagopal Sekhar.
The improvements in oxidative stress, glutathione levels and mitochondrial function in the muscle tissue of older humans taking GlyNAC were similar to the improvements in organs such as the heart, liver and kidneys of aged mice supplemented with GlyNAC as reported in the researchers' recent publication. Taken together, the results of these studies show that GlyNAC supplementation can improve these defects in many different organs of the body. "GlyNAC supplementation in aging mice increased their length of life mice by 24%," said Sekhar. "Gait speed is reported to be associated with survival in older humans. Our randomized clinical trial found a significant improvement in gait speed in older humans supplemented with GlyNAC. This raises the interesting question of whether GlyNAC supplementation could have implications for survival in people."
(Excerpt) Read more at medicalxpress.com ...
My wife and I have been taking this the past three months of so. We feel more energetic and, strangely, my kidneys seem to filter quicker, but a prior study did say eGFR improved.
GlyNAC is simply equal amounts of the amino acid Glycine and N-acetyl-cysteine (NAC). Nestle bought the rights to the patent for its Celltrient subsidiary, but you can make it on your own for a lot less.
Nestle says to take 2,400 mg if GlyNAC a day, which is 1,200 mg of Glycine and 1,200 mg of NAC, equivalent.
I’ve been taking 1,000 mg NAC 2X per day (2,000 mg / day) since the pandemic started. What brand Glycine do you prefer?
I was purchasing Now Supplements NAC on Amazon, but switched to direct-ordering NAC from Thorne Research when Amazon caved to the FDA and quit selling it.
For powder, NOW. For capsules, we had DoubleWood.
Powder is cheapest and glycine tastes sweet.
Just take the glycine at the same time as the NAC.
Where do you find your Glycine and NAC? Thanks.
Bttt
ping
Looks like Amazon has started selling it again.
NAC from Swanson Vitamins on sale at 35% or even 40% off (you have to get the nearly daily emails to get those sale notices and click through from the email). Glycine we get the powder form from NOW and capsules from DoubleWood. Powder is far cheaper for Glycine.
For later.
Yeah pandemic is over and vaxxes were a fraud so they can quietly release these again after libs took all homemade treatments off market for big pharma. I’ll take me some NAC and glycine
DoubleWood? That’s a catchy name for a product.
Later.
-PJ
Same here.
bkmk
Bookmark
bookmark
Bmk
I’ll know we’re back to normal when horse paste Ivermectin gets back to around $5 a tube. It was $4 in late Fall 2020.
ConservativeMind wrote:
“
More to the write up at the link.
My wife and I have been taking this the past three months of so. We feel more energetic and, strangely, my kidneys seem to filter quicker, but a prior study did say eGFR improved.
GlyNAC is simply equal amounts of the amino acid Glycine and N-acetyl-cysteine (NAC). Nestle bought the rights to the patent for its Celltrient subsidiary, but you can make it on your own for a lot less.
Nestle says to take 2,400 mg if GlyNAC a day, which is 1,200 mg of Glycine and 1,200 mg of NAC, equivalent.
“
Bookmarked!!!
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