Posted on 07/29/2022 1:34:12 PM PDT by ConservativeMind
Hormone therapy for prostate cancer increases the risk of cardiovascular disease-related death especially in older men, according to a population study involving more than 13,000 patients.
The highest risk was for coronary heart disease and stroke. The increased risks were apparent from the second year after cancer diagnosis and were more pronounced in older men.
"Hormone therapy is often used for patients with prostate cancer," says lead author Justinas Jonusas. "Our results suggest clinicians should consider risk reduction and mitigation strategies for cardiovascular disease when developing a treatment plan for men diagnosed with prostate cancer, particularly for older patients."
The researchers found:
- a more than two-fold increase in the risk of death from cardiovascular disease in men who had received hormone therapy.
- a higher risk of cardiovascular disease-related death from the second year onwards following a prostate cancer diagnosis.
- an almost five-fold higher risk in the 70 to 79 age group of those who received hormone therapy compared to those who did not.
The team also assessed the risk of death from several subtypes of cardiovascular disease, identifying there was a higher risk of dying specifically from stroke or coronary heart disease. These risks were 42% and 70% higher, respectively, in men treated with hormone therapy compared to those who were not.
"Prostate cancer is typically diagnosed in older men, over 65 years or older—and many of them will have already been diagnosed with cardiovascular disease," says Jonusas. "It is therefore concerning that we found such a tremendous increase in the risk of cardiovascular disease-related death in elderly males receiving hormone-lowering drugs. Consequently, we would like to express our notion that this group of patients should be screened for pre-existing cardiovascular disease and their risk factors to minimize the risk of dying from these conditions."
(Excerpt) Read more at medicalxpress.com ...
I feel the same way.
Any comment on ORGOVYX?
I believe this covers all forms of this therapy.
However, you have a more convenient form you are able to take.
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