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Increased Risk of Serious Blood Clots Up to Six Months After COVID-19
https://scitechdaily.com ^ | JULY 12, 2022 | By BMJ

Posted on 07/12/2022 9:58:44 AM PDT by Red Badger

Research uncovered an increased risk of pulmonary embolism (a blood clot in the lung) up to six months after covid-19 infection, deep vein thrombosis (a blood clot in the leg) up to three months, and a bleeding event up to two months. The study from Sweden was published by The BMJ.

According to the findings, there is also a higher risk of events in patients with underlying conditions (comorbidities), patients with more severe covid-19, and during the first pandemic wave compared with the second and third waves.

These results support measures to prevent thrombotic events (thromboprophylaxis), especially for high-risk patients, and strengthen the importance of vaccination against covid-19, according to the researchers.

It is already well established that covid-19 increases the risk of serious blood clots (known as venous thromboembolism or VTE), but less evidence exists on the length of time this risk is increased, if risk changed during the various pandemic waves, and whether covid-19 also increases the risk of major bleeding.

To address these uncertainties, scientists set out to measure the risk of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19.

Using national registries in Sweden, they identified more than one million people with confirmed SARS-CoV-2 infection (the virus responsible for covid-19) between February 1, 2020 and, May 25, 2021, matched by age, sex, and county of residence to more than four million people who had not had a positive SARS-CoV-2 test result.

They then performed two analyses: in the first, they calculated the rates of deep vein thrombosis, pulmonary embolism, and bleeding in covid-19 individuals during a control period (before and long after covid-19 diagnosis) and compared it to the rates in different time intervals after covid-19 diagnosis (days 1-7, 8-14, 15-30, 31-60, 61-90, and 91-180).

In the second analysis, they calculated the rates of deep vein thrombosis, pulmonary embolism, and bleeding during the period 1-30 days after covid-19 diagnosis in the covid-19 group and compared them to the corresponding rates in the control group.

The results show that compared with the control period, risks were significantly increased 90 days after covid-19 for deep vein thrombosis, 180 days for pulmonary embolism, and 60 days for bleeding.

After taking into account a range of potentially influential factors, the researchers found a fivefold increase in the risk of deep vein thrombosis, a 33-fold increase in the risk of pulmonary embolism, and an almost twofold increase in the risk of bleeding in the 30 days after infection.

In absolute terms, this means that a first deep vein thrombosis occurred in 401 patients with covid-19 (absolute risk 0.04%) and 267 control patients (absolute risk 0.01%). A first pulmonary embolism event occurred in 1,761 patients with covid-19 (absolute risk 0.17%) and 171 control patients (absolute risk 0.004%), and a first bleeding event occurred in 1,002 patients with covid-19 (absolute risk 0.10%) and 1,292 control patients (absolute risk 0.04%).

Risks were highest in patients with more severe covid-19 and during the first pandemic wave compared with the second and third waves, which the researchers say could be explained by improvements in treatment and vaccine coverage in older patients after the first wave.

Even among mild, non-hospitalized covid-19 patients, the researchers found increased risks of deep vein thrombosis and pulmonary embolism. No increased risk of bleeding was found in mild cases, but a noticeable increase was observed in more severe cases.

This is an observational study, so the researchers cannot establish cause, and they acknowledge several limitations which might have affected their findings. For example, VTE may have been underdiagnosed in patients with covid-19, testing for covid-19 was limited, especially during the first pandemic wave, and information on vaccination was not available.

However, results were largely consistent after further analyses, and are in line with similar studies on the association between covid-19 and thromboembolic events, suggesting that they withstand scrutiny.

As such, the researchers say their findings suggest that covid-19 is an independent risk factor for deep vein thrombosis, pulmonary embolism, and bleeding, and that the risk of these outcomes is increased for three, six, and two months after covid-19, respectively.

“Our findings arguably support thromboprophylaxis to avoid thrombotic events, especially for high risk patients, and strengthen the importance of vaccination against covid-19,” they conclude.

In a linked editorial, researchers at the University of Glasgow point out that despite the potential for new variants of concern, most governments are removing restrictions and shifting their focus to determining how best to “live with covid.”

However, they say this study “reminds us of the need to remain vigilant to the complications associated with even mild SARS-CoV-2 infection, including thromboembolism.”

Reference: “Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study” by Ioannis Katsoularis, Osvaldo Fonseca-Rodríguez, Paddy Farrington, Hanna Jerndal, Erling Häggström Lundevaller, Malin Sund, Krister Lindmark and Anne-Marie Fors Connolly, 6 April 2022, The BMJ. DOI: 10.1136/bmj-2021-069590

Funding: Region Västerbotten Agreement for Medical Education and Research funding, Umeå University, the Laboratory for Molecular Infection Medicine Sweden, Stroke Research in Northern Sweden, the Swedish Kidney Foundation, the Scandinavian Research Foundation for venous diseases, the Heart Foundation in Northern Sweden, Arnerska Research Foundation, and Kempes Foundation


TOPICS: Business/Economy; Health/Medicine; History; Society
KEYWORDS: bloodclots; chinavirus; clots; coronavirus; covid19; kungflu; longcovid; vaccine; vaccines; wuhanflu
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To: Manic_Episode; Retrofitted

Whoa...you guys got your vit d levels between 60-80???


21 posted on 07/12/2022 11:43:59 AM PDT by goodnesswins (....pervert Biden & O Cabal are destroying America, as planned. )
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To: Jane Long
Before I got fired and retired I was a building tech at a manufacturing facility of around 600 people of which the majority were 3rd worlders and mostly all vaxxed.

That 6 foot nonsense and the worthless mask protocols completely failed.

I wore the damn mask for 18 months but then they loosened the rule so that vaxxed employees could ditch the mask with proof, but the rest of us still had to wear one.

I refused citing my natural immunity as being superior to the vax.

I made them fire me, retired early and bought a house up north.

Life has never been better. The best revenge is living well.

22 posted on 07/12/2022 11:47:20 AM PDT by Manic_Episode (A government of the government, by the government, for the government)
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To: gitmo

“Haven’t they seen a lot of blood clots in people who were vaccinated and didn’t have COVID?”

Hell, yeah. They don’t call it the “clot shot” for nothing. Shots are way worse for clots than WuFlu is.


23 posted on 07/12/2022 11:52:50 AM PDT by MayflowerMadam
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To: goodnesswins
My daily supplement says vitamin D3 25mcg, 125%

I'm not much of a nutritionist but decently fit otherwise.

Is that not enough?

24 posted on 07/12/2022 11:54:54 AM PDT by Manic_Episode (A government of the government, by the government, for the government)
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To: Red Badger

will read later

thanx red


25 posted on 07/12/2022 12:03:32 PM PDT by thinden (buckle up.....)
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To: Red Badger
Increased Risk of Serious Blood Clots Up to Six Months After COVID-19 “vaccination”.

Huh, seems like they left “vaccination” out of that headline.

26 posted on 07/12/2022 1:01:59 PM PDT by Sicon ("All animals are equal, but some animals are more equal than others." - G. Orwell)
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To: Manic_Episode

Probably not...I have to take 5x that (250mcg) to keep my level around 60+. You MUST get tested. And also take appropriate Vit K with vit d3...most docs do not tell people this. It would reduce the amount of patients with problems.. 🙃


27 posted on 07/12/2022 1:08:32 PM PDT by goodnesswins (....pervert Biden & O Cabal are destroying America, as planned. )
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To: Big Red Badger
LOL Not really. The first time I got it was immediately after I went to the DMV. Second time was after my son went to Disneyland with some friends from high school. Third time was after my wife started a new job working concerts in an amphitheater. This last time has me stumped because I'm pretty much self-isolated and everyone else in my family tested negative.

On the plus side, the first time I almost went bye-bye -- fever hit 105 and stayed there for a bit before it broke and I was good. Second time I could not stay awake, ended up being just this side of a coma for two weeks, but no fever. Third time I felt like I had the creeping crud for two days and that was that. This time... well, I'm on FR so basically it's a cold. ;)
28 posted on 07/12/2022 6:41:06 PM PDT by Retrofitted
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To: Jane Long
DAMMIT! That's it! I couldn't figure out my fourth occurrence, but my wife tells me my friend I hung out with Sunday had just gotten a booster. Oh, I am so going to get my murder tools out for him!

Thank you, ma'am. Mystery solved!
29 posted on 07/12/2022 6:43:20 PM PDT by Retrofitted
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To: goodnesswins

LOL 88 as of 6/8 here. Thanks to some folks here I’ve been keeping an eye on that since this whole thing started (and my docs all say that’s likely what kept me going through the worst of it).


30 posted on 07/12/2022 6:47:00 PM PDT by Retrofitted
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To: Retrofitted

That’s Rough FRiend!
.
I had a deep,Rough cough that keep me awake for three nights Solid. I never had such a cough before or since. I’ve not had Flu or Cold since and That
Was Thanksgiving 2019 !
Back then I was working at a Major Facility with lots of Asian folks,,,
I’ve always liked my immune System.
Wuhan-——go Figure


31 posted on 07/12/2022 7:11:14 PM PDT by Big Red Badger (We Are JONAH)
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To: Retrofitted

Well...it is said that those with higher d3 levels are least likely to die!😁


32 posted on 07/12/2022 7:19:55 PM PDT by goodnesswins (....pervert Biden & O Cabal are destroying America, as planned. )
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