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Gut microbes differ in men with prostate cancer
Medical Xpress / European Association of Urology annual congress (EAU22) ^ | July 1, 2022 | Professor Peter Bostrom et al

Posted on 07/04/2022 1:16:47 PM PDT by ConservativeMind

Researchers have found a significant difference in the gut microbiota of men with prostate cancer, compared with those who have benign biopsies. Although the finding is an association, it could partly explain the relationship between lifestyle effects and geographical differences in prostate cancer.

Gut microbiota are the collection of microbes in the gastrointestinal tract and they affect processes and mechanisms in the body. The state of gut microbiota has been linked to many conditions, even in organs that are far from the intestines, but their role in prostate cancer is not understood.

Professor Peter Bostrom used samples collected from patients on a prospective multi-center clinical study. They sequenced the gut microbiota of 181 men who were suspected to have prostate cancer and undergoing prostate cancer diagnostics. The microbiota samples were collected at the time of their prostate biopsies after MRI scans.

Sixty percent of the men were diagnosed with prostate cancer, and their gut microbiota profiles were significantly different to those who had benign biopsies. The men with cancer had increased levels of Prevotella 9, members of the family Erysipelotrichaceae, and Escherichia-Shigella, a pathogen that causes diarrhea. They also had lower levels of Jonquetella, Moryella, Anaeroglobus, Corynebacterium and CAG-352 than men without.

Professor Bostrom says that "there are significant variations in prostate cancer rates around the world, which could be due to genetic factors or differences in healthcare policies, but also variance in lifestyle and diet. The difference in gut microbiota between men with and without prostate cancer could underpin some of these variations."

Prostate cancer is the most common male cancer globally. There is evidence that men who emigrate from low to high incidence areas have increased risk of prostate cancer in their lifetimes, and their offspring have the risk of the high incidence region.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cancer; erysipelotrichaceae; escherichiashigella; gut; prevotella9; prostatecancer; prostrate
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To: TexasKamaAina

You have a good cause.

There are better tests than the psa for prostate cancer, as you know.

The PCA-3 test for example.

https://www.cancerdefeated.com/finally-something-better-than-the-psa-test/


21 posted on 07/04/2022 5:22:26 PM PDT by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
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To: TexasKamaAina

There are other ways to use the PSA, but it would require sizing the prostate through ultrasound, MRI, or CT. Also, there are other markers to test (urinary PCA3 or SelectMDx test).

More, here:

https://www.pcf.org/about-prostate-cancer/what-is-prostate-cancer/the-psa-test/

I have had both a preventative CT and MRI done over the past few years to keep track of the size, and I encourage all men to consider such voluntary scans, if their doctors won’t prescribe them.


22 posted on 07/04/2022 5:30:22 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: TexasKamaAina

My doctor said he was the envy of everyone in medical school. His fingers are too short to do a prostate exam.


23 posted on 07/04/2022 5:59:03 PM PDT by gitmo (If your theology doesn't become your biography, what good is it?)
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To: WASCWatch

prostate cancer looking for advice

dob 1/29/55
super healthy til 3/2021
stage 4 in the bone
had surgery then chemo then hormone
psa went from 880 to .5
no ill effects from chemo take luptron every three months plus predestone daily
take some cell medicine out in the sun a lot
feel better than good
any advice much appreciated jim or genghis
genghistheteacher@yahoo.com


24 posted on 07/04/2022 6:22:38 PM PDT by genghis (Cathinkngact only reason go after puthan 5nu0 inbbiedComlpln)
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To: genghis

https://www.mayoclinic.org/diseases-conditions/prostate-cancer/expert-answers/prostate-cancer/faq-20057800


Study not conclusive by why take the risk?


25 posted on 07/04/2022 6:26:06 PM PDT by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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To: PeterPrinciple

My wife and I had sex 3-5 times per week when I was diagnosed. He’s on Lupron, so I doubt he is having sex on a regular basis.


26 posted on 07/04/2022 7:02:36 PM PDT by WASCWatch ( WASC)
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To: genghis

Where are you being treated?


27 posted on 07/04/2022 7:04:03 PM PDT by WASCWatch ( WASC)
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To: WASCWatch

Kaiser


28 posted on 07/04/2022 7:13:55 PM PDT by genghis (Cathinkngact only reason go after puthan 5nu0 inbbiedComlpln)
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To: MomwithHope

“Yep, kefir. Good for so many things.”

And tasty!


29 posted on 07/04/2022 7:42:59 PM PDT by Pete from Shawnee Mission ( )
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To: ConservativeMind

Yup.

Amazing effects of slow poisoning, huh?

But they’ll never admit it.


30 posted on 07/04/2022 8:05:09 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: TexasKamaAina

I’m on a mission to make sure as many men as possible don’t let their doctors rely strictly on the PSA to determine prostate health.
~~~~~~~~~~~~~~~~~~
See my post 23 at this link.... Dr. Stamey was an amazing individual. It takes a lot of guts to admit one is/was wrong, particularly after the PSA test had taken on the role that it had.

https://freerepublic.com/focus/f-chat/4076055/posts


31 posted on 07/04/2022 8:37:24 PM PDT by hecticskeptic ( )
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To: TexasKamaAina
.

"I’m on a mission to make sure as many men as possible don’t
let their doctors rely strictly on the PSA to determine prostate health."

.

Good for you!
I agree with you that the PSA test(s) are darn-near useless for
determining the status of prostrate cancer.

My dad was put on implanted hormone pellets for years due
to high PSA levels.

He suffered the nasty side effects of those hormone
treatments, until one day he said 'enough' - and told his doctor
to stop the things. "If I die, I die." he said.

But he lived for a number of years after that (made it to
89 years old), his cancer then went into remission all
by itself, and his PSA levels went back to normal.

And I am NOT convinced that he actually even had prostrate
cancer at all to begin with.

He ultimately passed away from COPD (cardio-obstructive pulmonary disease) -
from smoking cigarettes for 63 years from age 12 to 75 -
at age 89 - 3 months short of 90.

Good luck on your mission!

32 posted on 07/05/2022 7:01:21 AM PDT by GaltAdonis
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