Posted on 06/08/2022 9:33:13 AM PDT by SeekAndFind
Immunotherapy is the key to successful cancer treatment. Monoclonal antibodies are just one approach. Tumor vaccines directed at the foreign antigens that tumor cells feature are necessary. The problem is that tumor cells have afferent and efferent features that protect them from a host’s own immune system. They produce cytokines that stall phagocytosis of tumor cells by the dendritic cells. Processing of tumor antigen by the dendritic cells are key to triggering the T cell mediated delayed response that features CD4 lymphocytes and killer T cells. Without phagocytosis by the dendritic cells the immune charge never happens. Also the tumors feature surface proteins that protect them from any T lymphocytes that might get directed against them. The key is to disrupt these afferent and efferent tumor defense capabilities. One approach may be to first freeze a resected tumor to kill it, then slice it into thin slices and let it soak in saline. the remaining cytokines will then diffuse away. Then take the slices and soak it in a urushiol oil bath. Urushiol is the oil in poison ivy that causes a severe rash which is a classic delayed T cell firestorm. The urushiol will bind to the tumor antigens. Then the tumor slices in the urushiol bath would be macerated. This would be your cutaneous tumor vaccine. It would then be applied to an area of the skin. The dendrites of the skin, the Langerhans cells, would then hopefully phagocytize the urushiol/tumor antigen compounds and start an anti tumor immune response that would attack viable tumors elsewhere in the body. Of course this does not address the efferent tumor defense mechanisms such as the tumors defensive surface proteins However its been long noted that tumor cells avidly concentrate potassium and have a much higher intracellular level of potassium than normal cells. They maintain this gradient by use of the so called ATPase pump. This pump is weakened by digoxin. Concurrent digitalization of the patient when applying the vaccine may be useful.
This is only a theory and has never been tested. However if cancer is to be stopped, IMHO it will due to the successful development of some sort of tumor vaccines. Cancers are a failure of the host’s immune system.
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If it is a real cure I bet it disappears and never sees the market.
Meh. It’ll come down with an expanded market.
My sister-in-law used up every bit of her $1,000,000 insurance maximum on cancer treatment. She succumbed to the disease. I’m thinking this is a bargain as well.
My wife’s chemotherapy treatments twenty years ago had a list price of $13k every three weeks and she didnt make it.
I’m sorry to hear that. I don’t know what my wifes chemo cost but she did make it. It was very traumatic. She lost so much weight and their expensive anti-nausea medicine didn’t work. Very bad experience.
I was just reading about this: https://www.marca.com/en/lifestyle/us-news/2022/06/09/62a131e8e2704ef16e8b45df.html#
Huge if true.
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