Posted on 05/17/2022 7:53:57 PM PDT by ConservativeMind
A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC—a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione—could improve many age-associated defects in older humans.
The results of this study show that older humans taking GlyNAC for 24 weeks saw improvements in many characteristic defects of aging, including glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, body fat, genomic toxicity, muscle strength, gait speed, exercise capacity and cognitive function. The benefits declined after stopping supplementation for 12 weeks. GlyNAC supplementation was well tolerated during the study period.
Animal studies conducted in the Sekhar lab have shown that restoring glutathione levels by providing GlyNAC reverses glutathione deficiency, reduces oxidative stress and fully restores mitochondrial function in aged mice.
"We worked with eight older adults 70 to 80 years of age, comparing them with gender-matched younger adults between 21 and 30 years old," Sekhar said. "We measured glutathione in red-blood cells, mitochondrial fuel-oxidation, plasma biomarkers of oxidative stress and oxidant damage, inflammation, endothelial function, glucose and insulin, gait-speed, muscle strength, exercise capacity, cognitive tests, gene-damage, glucose-production and muscle-protein breakdown rates and body composition. Before taking GlyNAC, all these measurements were abnormal in older adults when compared with those in younger people."
The older participants took GlyNAC for 24 weeks, and then stopped it for 12 weeks.
"We are very excited by the results," Sekhar said. "After taking GlyNAC for 24 weeks, all these defects in older adults improved and some reversed to the levels found in young adults." The researchers also determined that older adults tolerated GlyNAC well for 24 weeks. The benefits, however, declined after stopping GlyNAC supplementation for 12 weeks.
(Excerpt) Read more at medicalxpress.com ...
Ping to the fountain of youth ( sorta)
“The cost to make it yourself can be as low as 12 cents a day. “
That’s the best part. It’s nice to read for once that you don’t have to add another $39.95 bottle of something to the monthly buy list.
Isn’t NAC the supplement that Amazon quit carrying because people said it was effective against Covid?
Here’s info on that from the Covid meta study people:
I see you can get it at Amazon now, but only from 2-3 vendors, which leads me to think it was banned for a while.
Started making my own glycine capsules a couple months ago after reading one of the studies. 8oz of glycine powder and 1000 capsules was all of $21. A bit tedious filling the capsules but the savings is worth it. Based on my calculations filling the capsule 50% is the correct amount. 8oz of powder will last a year easily.
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THANKS FOR THE MAKE YOUR OWN INSTRUCTIONS!!! >>>>>> I will see about the two powders today.
I also hear that glycine is good as a sweetener for tea, coffee etc.
https://www.healthline.com/nutrition/glycine#TOC_TITLE_HDR_4
“Isn’t NAC the supplement that Amazon quit carrying because people said it was effective against Covid?”
NAC POWDER >>> It is all over eBay >>>>> https://www.ebay.com/sch/i.html?_from=R40&_trksid=p2334524.m570.l1311&_nkw=nac+powder&_sacat=0&LH_TitleDesc=0&_odkw=NAC+the+supplement+&_osacat=0
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What about just dropping a small spoonful (correct amount size) of the power into some drinkable liquid and gulping that down? Pop it in the morning coffee??
NAC
100 capsules
600mg
$22.99
https://www.vitaminshoppe.com/p/nac-acetyl-l-cysteine-600-mg-100-capsules/vs-1295
I started taking NAC about 6 months ago and I just feel better, somehow. Stronger, breathing better too. I had a 3-4 day bout with covid (not vaxed) and doubled dose for a week. I think it made a difference but I can’t prove it.
I’ve read a bit about it but am atill unclear on some of the information. Anyway, I get mine from Thorne and it’s nowhere near as cheap as the thread says it CAN be, lol. I’m always hesitant to diy supplements. I take it on an empty stomach 30 minutes before breakfast.
Great thread!
I’ve got NAC and so many supplements I rattle when I walk.
The good news you are super healthy. The bad news you are dead broke and living on some sidewalk from all those $29.95 and $39.95 bottles of health magic. haha
Wait 30 minutes before taking something else.
It’s the compound that matters, not taking sulphur.
These are different compounds.
Yes, this is what Amazon banned last year, seemingly in response to FDA overtures around wanting to reassess it for prescription status.
This may be the best advertisement yet as to NAC’s usefulness and effectiveness. If it might be bad for Big Pharma, they’re against it. One of the big lessons of Covid is that many (most?) politicians, the media, big public health (CDC, FDA, NIH) are all in the pocket of Big Pharma. This is a lesson in regulatory capture and beyond.
Swanson Vitamins sometimes has it for $7.33 a bottle of 100 capsules (600 mg).
There seems to be at least 3 Nestle products with the Celltrient name: Protect, Energy and Strength. One is a NAD product, one(this) is a glycine/NAC product(not available on Amazon because of NAC) and one is a Urolithin A product. The studies I see(and have been posted here in the last few days) seem to suggest all three are important. In other words, it would be a 3 pill regime whether using Nestle or a health/vitamin shop.
https://www.nestlehealthscience.com/newsroom/press-releases/celltrient
Again, thanks for posting these. I see these stories nowhere else.
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