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Allergic-like CT contrast reaction raises MRI contrast risk
Medical Xpress / Radiological Society of North America / Radiology ^ | Feb. 22, 2022 | Yoon Hae Ahn et al

Posted on 02/23/2022 1:08:36 PM PST by ConservativeMind

People with a history of allergic-like reactions to iodinated contrast media, which is used in a variety of X-ray-based procedures, such as CT and angiography, are susceptible to similar reactions from commonly used MRI contrast agents. The study also found that premedication or switching to a different MRI contrast agent may reduce risk in patients who have had previous contrast agent reactions.

Gadolinium-based contrast agents (GBCA) have long been used to improve visualization of organs, tissues and blood vessels on MRI and provide a more accurate depiction of disease. Although GBCA are relatively safe, recent studies have reported several adverse reactions related to their use, including allergic-like hypersensitivity reactions, such as rash and flushing.

The risk of allergic-like hypersensitivity reactions to GBCAs was higher in those with a history of similar reactions to iodinated contrast media. Traditionally, a history of iodinated contrast media hypersensitivity was not considered as a risk factor for hypersensitivity to GBCAs and vice versa, owing to the structural and compositional differences between the two.

"The results of our study challenge this idea," Dr. Kang said.

"Thus, physicians should be aware that patients with a history of hypersensitivity to one of iodinated contrast media or GBCA are at greater risk of developing hypersensitivity reactions to the other," she said.

Analysis of the data showed that premedication, typically with steroids and antihistamines, and changing the GBCA showed preventive effects in patients with a history of acute allergic-like hypersensitivity reactions. Patients who received premedication and before MRI or were switched to a different GBCA showed the lowest rate of recurrence. Only premedication significantly reduced the incidence of reactions in patients with a history of delayed reactions.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
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To: Ladysforest

damn...


21 posted on 02/23/2022 4:28:42 PM PST by Chode (there is no fall back position, there's no rally point, there is no LZ... we're on our own. #FJB)
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To: eyeamok

Wow! Maybe you have a lot of iron in your body?

Outside of metal implant causing problem in an MRI, you are the first I’ve heard of having this problem.

Thankfully, it will disappear soon.


22 posted on 02/23/2022 4:38:24 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I have had a few surgeries, complete blood workup , nobody has ever said anything, all normal.

I went for the MRI after my back went out while I was sleeping, I couldn’t hardly walk, my whole leg went numb,stiff and painful after 25-50 feet.

The MRI Fixed my Back Overnight, but I have the weirdest side effect that has baffled everyone. I have been Warned by All that if I get an MRI on my head or my upper body I will probably Die in the Tube


23 posted on 02/23/2022 4:52:54 PM PST by eyeamok (founded in cynicism, wrapped in sarcasm)
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To: Scarlett156

No, but my timing wasn’t good- I should’ve waited until the end of the test instead of at the beginning. Not a pleasant experience 😵‍💫


24 posted on 02/23/2022 5:10:46 PM PST by telescope115 (Proud member of the ANTIFAuci movement. )
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To: telescope115

Did anyone laugh or did they wait until you were out of earshot?


25 posted on 02/24/2022 5:47:01 AM PST by Scarlett156 (Someone with "comedian" on his social media profile is invariably a self-hating sadistic loser.)
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To: Scarlett156

I don’t know, I just got the hell outta there….


26 posted on 02/24/2022 7:11:14 AM PST by telescope115 (Proud member of the ANTIFAuci movement. )
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To: YouGoTexasGirl

Bkmk


27 posted on 02/24/2022 12:41:25 PM PST by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
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