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Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities
JAMA Network ^ | 2/18/2022 | Multiple

Posted on 02/18/2022 10:34:14 AM PST by semimojo

Question: Does adding ivermectin, an inexpensive and widely available antiparasitic drug, to the standard of care reduce the risk of severe disease in patients with COVID-19 and comorbidities?

Findings: In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone.

Meaning: The study findings do not support the use of ivermectin for patients with COVID-19.

(Excerpt) Read more at jamanetwork.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: covid; ivermectin; jama; jamastudy
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To: norsky
...how much you getting paid for your disinfo.

Hey, it cost me a lot to organize and execute a 5 month randomized study in Malaysia.

Then I had to pay for the results to be written up and had to bribe the JAMA to publish it.

Don't you think I deserve a little compensation?

61 posted on 02/18/2022 6:04:47 PM PST by semimojo
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To: curious7

“The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups: oral ivermectin alone (12 mg once daily for 5 days), oral ivermectin in combination with doxycycline (12 mg ivermectin single dose and 200 mg doxycycline on day 1, followed by 100 mg every 12 h for the next 4 days), and a placebo control group. Clinical symptoms of fever, cough, and sore throat were comparable among the three groups.”

So this says that ivermectin did not have a significant effect on people with Covid.


62 posted on 02/18/2022 6:50:41 PM PST by DennisR (Look around - God gives countless clues that He does, indeed, exist.)
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To: aquila48
Thanks for your civil response. (genuinely)

I would absolutely agree if done by honest but admitted skeptics.

But it won't happen, in my opinion. It would be the equivalent of the tree falling in the woods. I think the massive boluses of money have cleared out the honest but admitted skeptics.

In COVID and the forcing of mass vaccinations, I think there is too much money at stake. Tens of billions, if not hundreds of billions to admit any interruption in the gravy train. You may get the vaccination "for free" but...***someone*** is paying for that dose of vaccine we are being forced at the point of a legislative gun to accept.

Too many people are getting offers they cannot refuse.

A good example of that is the case of Dr. Andrew Hill who did a study on the effectiveness of Ivermectin that he and Dr. Tess Lawrie had agreed would be included in her meta-analysis of 40 studies that supported using it in treatment regimens.

Dr. Hill's conclusions were very positive, but right before the study was published, out of the blue and with no warning, he changed his conclusions. It still had the same underlying data, was still the same study, but the conclusion had changed to a negative one. When Dr. Lawrie called him to ask why he had changed it, he said that his his study had been funded by Unitaid (a Bill Gates vaccine endeavor) which paid Dr. Hill's employer (the University of Liverpool) $40 million dollars, and that they had changed the findings as was their contractual right, and...he had to either go along with it or reject the money.

She called him out on it, and he admitted it. The point is, that was just one example. There is a lot of money out there based on this, and the people holding the purse strings are calling the shots and the formerly ethical researchers have gone along with it for the money.

Bill Whittle had an excellent take on this aspect of things: CERBERUS: How Natural Enemies Cooperate to Control Your Power, Money and Information

It is a ten minute video, and well worth the time.

I know this sounds very cynical. I am extremely cynical about this. I am currently under a ticking vaccine mandate. My current employer is extremely Leftist, and my formerly conservative hospital merged with them some years ago, and they have largely taken over decision making enterprise wide. Just the other day, they sent a mass email to employees about the need to fight White Supremacy. This in a stupidly blue state.

I am very disillusioned about this.

I have been working in healthcare for nearly forty years, and cannot believe healthcare has gone along with this, not to mention medical research, with Government, Big Pharma and the Media colluding in this (that is the point of the video above-Cerberus, the three headed monster dog that guards the gates of Hell in the form of those three entities)

I have taken part in research studies, and while I understood the profit motive and supported it, what we have seen here with the massive amounts of government money and influence FORCING people to be REQUIRED to accept this invasive and untested medical procedure is astonishing to me.

63 posted on 02/18/2022 9:05:31 PM PST by rlmorel (The concept of a "cashless society" is simply a vector for the exercise of tyranny.)
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To: bk1000; qaz123; SoConPubbie; DennisR; dkGba; ransomnote; semimojo; jacknhoo; Steve_Seattle; ...

Were you taking anything else like zinc, Vitamin D3 or C, multi vitamin/mineral, The Malasian study did not use any of these things, unless they were included in their “standard care” which was not explained. Below is the word on the Uttar Pradesh, India public health effort which was so successful. It used all of the above and other items as well along with screening, testing, and teaching. Any study of “Ivermectin” needs to be examined carefully to see what else, if anything, was also included. The Indian study was just called Ivermectin which was a completely incomplete identifier. The Indian study was definitely influenced by the Zelenko approach as modified with more experience.

https://www.cureus.com/articles/76496-therapies-to-prevent-progression-of-covid-19-including-hydroxychloroquine-azithromycin-zinc-and-vitamin-d3-with-or-without-intravenous-vitamin-c-an-international-multicenter-randomized-trial

Some people receiving Ivermectin have reported feeling a lot better than they have in years. Some of these people may have been infected with something else at a low level which may have been healed by Ivermectin. If one has lived in rural areas, traveled or served in foreign countries, there is always the possibility of some kind of parasitic infection and residual at a low level, not strong enough to encourage medical diagnosis. The article below describes the many kinds of parasitic diseases, and the hundreds of millions of people infected by some of them. Ivermectin is used to treat some, and others may now be the subject of Ivermectin research. In vitro (test tube) research has been done on some, but has not yet been carried on to in vivo (in alive creatures including humans) studies which have their own problems. What works in vitro does not always work in vivo, and optimum doses need to be worked out.

https://meridian.allenpress.com/journal-of-parasitology/article/106/6/859/451163/Parasites-and-Parasitology-in-this-SARS-CoV-2

Here is an excellent article on the many other diseases that can lead to chronic low level illness including in Lyme patients, particularly in the US.
https://www.lymedisease.org/members/lyme-times/special-issues/coinfection-issue/how-can-i-get-better/

Here is a unique trial of Ivermectin to eliminate West Nile Virus in the environment.
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007210


64 posted on 03/08/2022 10:24:13 AM PST by gleeaikin (ould the , vitamins,Question authority!)
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To: semimojo

Hi.

Reading the study, it appears the sample size was 1000 m/f patients.

Did I miss something?

5.56mm


65 posted on 03/08/2022 10:32:39 AM PST by M Kehoe (Quid Pro Joe and the Ho need to go.)
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To: M Kehoe

Also, the study didn’t mention The double blind control parameters.

I could have missed it.

5.56mm


66 posted on 03/08/2022 10:35:11 AM PST by M Kehoe (Quid Pro Joe and the Ho need to go.)
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To: gleeaikin

The people that I know, that took it, we’re on the various protocols: ivermectin, doxycycline, ZPack, zinc, Vit D, prednisone.

2 of 3 said they had never felt better after finishing up with the regimen.


67 posted on 03/08/2022 10:36:42 AM PST by qaz123
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To: M Kehoe
Reading the study, it appears the sample size was 1000 m/f patients.

"a total of 500 patients (250 patients for each group) were recruited."

68 posted on 03/08/2022 11:00:57 AM PST by semimojo
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To: gleeaikin

I use a variety of things, some of which I was already using for other purposes: Vitamin C; Vitamin D3; Zinc; Quercetin, NAC; Nigella Sativa; probiotics; Quinine bark (Chinchona); Melatonin; fish oil; L-Lysine; a couple of nasal sprays (one with povidone iodine); Selenium; multiple vitamins; and mouthwashes that contain a certain ingredient (povidone iodine or one I can’t recall the chemical name of right now).


69 posted on 03/08/2022 11:02:23 AM PST by Steve_Seattle
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To: semimojo

Does JAMA normally publish study results of sample sizes that small?

5.56mm


70 posted on 03/08/2022 11:19:47 AM PST by M Kehoe (Quid Pro Joe and the Ho need to go.)
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To: M Kehoe
Does JAMA normally publish study results of sample sizes that small?

I don't know. The sample size was at the minimum needed to get a decent confidence interval.

71 posted on 03/08/2022 11:36:53 AM PST by semimojo
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To: bk1000; qaz123; SoConPubbie; DennisR; dkGba; ransomnote; semimojo; jacknhoo; Steve_Seattle; ...

I made a mistake in my Comment #64. The first link from Cereus was actually a study in Turkey which effectively used HCQ as in the original Zelenko Protocol which he has modified with newer information. The also successfully used IV Vitamin C for part of this trial. The most fascinating finding from this Turkish study was not even part of the trial. It was found in the preliminary tests of prospective trial participants. They tested, among other things, blood Vitamin D levels of these sick people. After the trial was over they reviewed their preliminary screening data. They discovered that NOT ONE of their more than 200 participants had OPTIMUM VITAMIN D LEVELS. Their measurements were in nmol/L (nanomoles per liter). US uses ng/mL (nanograms per milliliter). The Turkish figures have to be divided by 2.5 to put into US figures.

In the US, Kaiser Permanente considere the OPTIMUM RANGE for blood Vitamin D to be 50 to 80 ng/mL. The Turkish study considered above 30 ng/ml to be OPTIMUM (75/nmol/L). No patient in their study was optimum by their lower standard. Three% were insufficient (between 20 and 30 ng/mL); 42% were deficient (between 10 and 19 ng/mL and 55% were SEVERELY DEFICIENT at below 10 ng/mL. The ONE DEATH was around 3 ng/mL. I think the logical conclusion is that TO STAY OUT OF HOSPITALS GET YOUR VITAMIN D LEVEL TO OPTIMUM! Get a blood Vitamin D test, and ask a knowledgeable doctor how much D to take to get to OPTIMUM.

The link below was what I had intended to link at Comment #64. It includes the exact components and methods used for the successful Uttar Pradesh, India, study.

https://www.thedesertreview.com/opinion/columnists/indias-ivermectin-blackout-—part-v-the-secret-revealed/article_9a37d9a8-1fb2-11ec-a94b-47343582647b.html


72 posted on 03/08/2022 11:42:07 AM PST by gleeaikin (ould the , vitamins,Question authority!)
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To: semimojo; P-Marlowe; Jane Long

Ivermectin group, 3 deaths.

Control group, 10 deaths.

You’d think they’d mention that.

It was exactly what happened to me. I was sick with covid and have 2 comorbidities. I progressed to very, very sick but refused hospital care.

This typing proves I didn’t die.


73 posted on 03/08/2022 11:47:36 AM PST by xzins (Retired US Army chaplain. Support our troops by praying for their victory. )
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To: semimojo

“The sample size was at the minimum needed to get a decent confidence interval”

Yep, about 4 standard deviations.

5.56mm


74 posted on 03/08/2022 11:49:48 AM PST by M Kehoe (Quid Pro Joe and the Ho need to go.)
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To: xzins

👍🏼

Yes, you’d think they *would* mention that.

Glad you recovered, and are still here typing, after receiving Ivm.

You’ve proven this Bangladeshi *study* irrelevant.


75 posted on 03/08/2022 12:03:48 PM PST by Jane Long (What we were told was a “conspiracy theory” in 2020 is now fact. 🙏🏻 Ps 33:12)
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To: xzins

The problem with these studies is that, for instance, this one used only ivermectin and nothing else. No zinc supplements, no D3 supplements, no HCQ or Quercetin. All the “non approved” protocols that work call for zinc and D supplements as a minimum. Ivermectin is useless if you have zinc or vitamin d deficiencies.


76 posted on 03/08/2022 12:21:30 PM PST by P-Marlowe (I got the <ΙΧΘΥΣ>< variant. Catch it. John 3:16)
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To: P-Marlowe; Jane Long

Correct. And antibiotics


77 posted on 03/08/2022 1:21:25 PM PST by xzins (Retired US Army chaplain. Support our troops by praying for their victory. )
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