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Vaccine effectiveness against hospital admission in South African health care workers who received a homologous booster of Ad26.COV2 during an Omicron COVID19 wave: Preliminary Results of the Sisonke 2 Study. PREPRINT
Sisonke-2 study, U of South Africa via Mexrxiv preprint server ^ | 29 December 2021 | Govt of South Africa

Posted on 12/30/2021 12:09:44 AM PST by blueplum

Following the results of the ENSEMBLE 2 study, which demonstrated improved vaccine efficacy of a two-dose regimen of Ad26.COV.2 vaccine given 2 months apart, we expanded the Sisonke study which had provided single dose Ad26.COV.2 vaccine to almost 500 000 health care workers (HCW) in South Africa to include a booster dose of the Ad26.COV.2. Sisonke 2 enrolled 227 310 HCW from the 8 November to the 17 December 2021. Enrolment commenced before the onset of the Omicron driven fourth wave in South Africa affording us an opportunity to evaluate early VE in preventing hospital admissions of a homologous boost of the Ad26.COV.2 vaccine given 6-9 months after the initial vaccination in HCW.

...We provide the first evidence of the effectiveness of a homologous Ad26.COV.2 vaccine boost given 6-9 months after the initial single vaccination series during a period of omicron variant circulation. This data is important given the increased reliance on the Ad26.COV.2 vaccine in Africa....

(Excerpt) Read more at medrxiv.org ...


TOPICS: Chit/Chat; Health/Medicine; Science
KEYWORDS: bluepill; boosterwindow; ccpvirus; foreverjab; infiniteboosters; infiniteposters; johnsonjohnson; lololololololololol; tcells; theboosterwindow; vaccines; vaxtardvoltron
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so what the Sisonke-2 has found, for review, is a single dose J&J followed in 6-9 months by a second dose, provided 63% protection against hospitalization risk after two weeks, strengthening to 85% defensive against hospitalization from Omi within 30 to 60 days.

This is in line with an previous Open Access study from Jun 2021, that J&J demonstrated gain of protective strength over time. This new study adds that the retained protection is possibly longer than that of mRna Pfitzer, may reset the booster window to 6 months, and, the protection remains effective against Omi. This study may also help understand the question of whether T-cells respond to all variants equally, as JJ seems to do. study here

1 posted on 12/30/2021 12:09:44 AM PST by blueplum
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To: blueplum
I'm confused.

Was this the sixth booster, or the seventh booster?   thinking face

2 posted on 12/30/2021 12:23:59 AM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: blueplum

how about 3 shots per year?

30 Dec: Guardian Australia: Up to three Covid jabs a year could be needed for protection, data suggests
UK analysis indicates Pfizer and Moderna boosters less effective against Omicron than Delta variant and appear to drop away further after nine weeks
by Peter Hannam
The analysis included 147,597 Delta and 68,489 Omicron cases in the UK. The agency stressed the “results should be interpreted with caution due to the low counts and the possible biases related to the populations with highest exposure to Omicron (including travellers and their close contacts) which cannot fully be accounted for”...

Jaya Dantas, a professor of international health at Curtin University, said it was still early days for the understanding of the efficacy of the vaccinations but “it appears that there might be a need for regular boosters”.
“You might need boosters, say maybe two a year or three a year,” Dantas said, with elderly people more likely to be in line for a triple annual dose...
https://www.theguardian.com/australia-news/2021/dec/30/up-to-three-covid-jabs-a-year-could-be-needed-for-protection-data-suggests


3 posted on 12/30/2021 12:44:09 AM PST by MAGAthon
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To: kiryandil

J&J is a one-shot and done adenovirus-based vaccine. So a second shot, 6-9? months out, would be a two-dose and done and give over a year’s protection possibly up to 18 months??? -

that timeframe needs review of course. But if HCWs were going 9 months on a single dose and not being infected, there must have been some sort of protection still active at 9 months, right?


4 posted on 12/30/2021 12:51:06 AM PST by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: blueplum
J&J is a one-shot and done adenovirus-based vaccine. So a second shot, 6-9? months out, would be a two-dose and done and give over a year’s protection possibly up to 18 months???

What I hear you saying is, two shots per year, or once every six months and that should do the trick.

One or two and done you say?


5 posted on 12/30/2021 1:02:00 AM PST by bagster ("Even bad men love their mamas".)
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To: bagster

That’s only analdoctal evidence as the jabbers like to say, lol.


6 posted on 12/30/2021 1:35:37 AM PST by OftheOhio (never could dance but always could fight - Romeo company)
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To: blueplum
I'm a scientist.

You're a believer.  winking face

7 posted on 12/30/2021 1:41:19 AM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: bagster

There’s no reasoning with vaxtards. They want to push the death shot on everyone. Deep down they know the truth that these injections will kill them within the next few months to couple of years so they want to talk the high IQ people who know better into taking it. Not gonna happen. EVER.


8 posted on 12/30/2021 1:42:24 AM PST by ForbesFan
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To: OftheOhio; bagster
"analdoctal evidence"

 face with tears of joy  face with tears of joy  face with tears of joy  face with tears of joy

9 posted on 12/30/2021 1:42:34 AM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: bagster

At least no more than twice as many shots as before.


10 posted on 12/30/2021 1:48:54 AM PST by gitmo (If your theology doesn't become your biography, what good is it?)
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To: blueplum
Impressive numbers.

However, they are not meaningful unless compared to an un-vaccinated control group.

For instance, the Covid fatality rate in South Africa has dropped 80% since Omicron became the dominant variant.

But, just 30% of South Africans are vaccinated.

11 posted on 12/30/2021 1:55:29 AM PST by zeestephen
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To: blueplum
I've spent a lot of time studying the issue of declining effectiveness of the covid "vaccines." After two years of 12 hour per day, six days per week intense research it is now clear to me that covid could be eliminated from the earth and from everyone's imagination only if everyone was "vaccinated" twice per day, every day, for at least seven consecutive years.

That would only be effective if everyone on earth also triple masked, 24/7/365, stayed at least 400 feet apart at all times (NO exceptions) and pulled an extra large, rooster-headed Magnum condom over their heads.

Additionally, I discovered that pulling two condoms over one's head works 56.9% better than a single one. Also it appears that dancing the "Watusi" like a lunatic while listening to hardcore punk rock further reduces the risk of catching all future versions of covid, real or imagined, by 600 percent.

Anything less than this comprehensive approach will result in everyone on earth dying within 2 months.

12 posted on 12/30/2021 2:09:24 AM PST by Rocco DiPippo (I)
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To: OftheOhio; kiryandil
That’s only analdoctal evidence as the jabbers like to say, lol.


13 posted on 12/30/2021 2:15:25 AM PST by bagster ("Even bad men love their mamas".)
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To: blueplum

Sounds awfully complicated for the sniffles.


14 posted on 12/30/2021 2:16:01 AM PST by Libloather (Why do climate change hoax deniers live in mansions on the beach?)
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To: Rocco DiPippo

“...and then, the witch doctor, he said, he said to me...”


15 posted on 12/30/2021 2:19:33 AM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: ForbesFan

injections will kill them within the next few months to couple of years

talk about a ‘tard statement. What rocket scientist told you that tall tale? Thats been circulating since Dec 2020. Another six months and it’ll be revised to ‘you just wait 5 years or 10 years’

Speaking of Dec 2020, read a story today about the first nontrial vaccinated person - california ICU nurse - one year anniversary on Christmas eve. Still at work. Still saving lives in the ICU. No plans on dying. Thought you might like to know.


16 posted on 12/30/2021 2:21:34 AM PST by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: Libloather

“sniffles” don’t pay for the new deck on the second house on the lake, or the new pontoon party barge at the first house on the lake.


17 posted on 12/30/2021 2:23:36 AM PST by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: kiryandil; blueplum
I'm a scientist. You're a believer.

🎵

Cheer up, sleepy blueplum
Oh, what can it mean
to a vaxxine believer
And a derp vaxtard queen

🎵

#HeyHeyWereTheMudbloods


18 posted on 12/30/2021 2:26:21 AM PST by bagster ("Even bad men love their mamas".)
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To: blueplum
No plans on dying.

Just a few questions:

a.) Do many people 'plan on dying'?

c.) Do viruses kill every living human on the planet? Why not?

d.) Do fake poison vaccines kill every living human on the planet immediately?

e.) Were you dropped on your head as a child?

Its open book. Take your time.


19 posted on 12/30/2021 2:32:19 AM PST by bagster ("Even bad men love their mamas".)
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To: Rocco DiPippo

LOL - you are indeed certifiably weird if you’re trying to fit condoms on your head.


20 posted on 12/30/2021 2:34:54 AM PST by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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