On COVID-19 Vaccines, the Chickens May Be Coming Home to Roost: Vaccines may put evolutionary pressure on the virus to mutate to evade protection

Early in the Delta wave of the pandemic, I remember an emphatic statement from Dr. Robert W. Malone. As Florida and the rest of the South began seeing increased cases, the drumbeat to get vaccinated became incessant. Governor Ron DeSantis was in the process of revolutionizing the delivery of monoclonal antibodies amid criticism from the media and our vaunted expert class for treating the ill rather than pushing vaccines. When an interviewer asked Dr. Malone about Florida’s response, he said: “You don’t vaccinate into the teeth of a pandemic.”

Malone made that comment in the context of a more extended discussion about how viruses evolve and how mass vaccination could encourage the emergence of variants. I did my best to explain that complicated conversation in an earlier article about experiments with vaccination for Marek’s disease in chickens. In infection-naive populations, the vaccinated chickens incubated more virulent strains of the virus. These strains were deadly to the unvaccinated in the flock.

Vaccines may pressure a virus to mutate to evade the protection the vaccine provides. Simultaneously, the vaccinated chickens could survive the more virulent strains without becoming severely ill. It appears the chickens may be coming home to roost.

A study in preprint from the University of California San Francisco (UCSF) and the San Francisco Department of Public Health shows that vaccinated individuals with symptomatic breakthrough cases have a higher load of antibody-resistant SARS-CoV-2 variants. It also demonstrated that viral loads in symptomatic cases were similar whether the patients were vaccinated or unvaccinated.

“Taken together, our results suggest that vaccine breakthrough infecions are overrepresented by circulating antibody-resistant SARS-CoV-2 variants, and that symptomatic breakthrough infections may potentially transmit COVID-19 as efficiently as unvaccinated infections, regardless of the infecting lineage.”

HOW THE RESEARCH WAS DONE:

The researchers did complete genome sequencing and retrospective chart reviews to determine the virus lineage in each infected patient and identify whether individuals experience symptoms. This concluded at the end of June. However, even at that point, researchers noted that symptomatic vaccinated patients had low or no detectable neutralizing antibodies. This finding is consistent with the waning vaccine efficacy, which the CDC has acknowledged.

While the researchers acknowledge some limitations to their study, they assert that their results indicate a highly vaccinated community puts evolutionary pressure on the virus. Individuals who are fully vaccinated are also more likely to carry antibody-resistant variants of concern.

RE: Why didn’t Polio, or Rubella, or any other viruses out mutate their vaccines?

Maybe because :

1) They are different types of viruses. Coronaviruses like Covid-19 are like the flu and cold virus, they mutate faster.

2) The prevalent mRNA vaccines are different from the vaccines developed for Polio and Rubella.

Why didn’t Polio, or Rubella, or any other viruses out mutate their vaccines?

Every case is different. Respiratory viruses generally mutate faster; the real vaccines were "debugged".

What you don't do categorically is put pressure on a virus which is insufficient to eliminate it -- and this is what Covid "vaxxes" do.

And this logic applies not just to viruses and vaccines: about the worst thing one can do is to treat bacterial infection with antibiotics and not complete the treatment... this creates resistant strains. Resistant TB is out there already. --

This is something that is known to every epidemiologist and this raises the real question: are the people in CDC et al totally incompetent, or perhaps they did know what they were doing and were trying to make the epidemics worse?

“ The prevalent mRNA vaccines are different from the vaccines developed for Polio and Rubella.”

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Johnson & Johnson, and AstraZeneca are Not mRNA vaccines. They are the more traditional type.

Why didn’t Polio, or Rubella, or any other viruses out mutate their vaccines?

Because, unlike the current crop of mRNA vaccines, the vaccines introduced to address polio and rubella were not "non-sterilizing." Indeed, the initial Salk polio vaccine was in the nature of a non-sterilizing vaccine, and its introduction was halted as evidence emerged that the vaccine was making things worse.

"Simultaneously, the vaccinated chickens could survive the more virulent strains without becoming severely ill."

So it's possible that it is the vaccinated who pose a threat to the unvaccinated, the exact opposite of what we've been told? Ironic as it may be, there's no consolation in that for me. Maybe the fact that I can't go to the local bar anymore is a good thing for MY safety.

“ They use a so-called “adenovirus” technology, which is NOT the same as traditional vaccines which use inactivated or weakened strains of a virus.”
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Adenovirus is not technology, it’s a type of virus it effects mostly the respiratory system.

https://www.cedars-sinai.org/blog/what-is-adenovirus.html

https://www.mayoclinic.org/johnson-johnson-adenovirus-vaccine-explained/vid-20510091

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