Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Eating spinach could protect against colon cancer (due to fatty acids and linoleic acid derivatives)
Medical XPress / Texas A&M University / Gut Microbes ^ | Sept. 23, 2021 | Lindsey Hendrix / Ying-Shiuan Chen et al

Posted on 09/23/2021 12:05:01 PM PDT by ConservativeMind

A new study from Texas A&M Health suggests eating spinach could prevent colon cancer. And now, building on previous work, researchers are closer to understanding exactly how it works.

In the United States, colon cancer is the fourth-most common cancer and second-leading cause of cancer-related deaths. Previous studies have shown that eating green vegetables and fiber reduces risk of colon cancer by as much as half. This new study, recently published in the journal Gut Microbes, explores the relationship between spinach, gut health, genes and colon cancer outcomes.

After feeding freeze-dried spinach to an animal model of familial adenomatous polyposis for 26 weeks, the researchers observed significant antitumor activity in the colon and small intestine. Using an unbiased approach called multi-omics, the researchers found that the tumor suppression by spinach involved increased diversity in the gut microbiome (helpful microbes) and changes in gene expression to help prevent cancer. They also found that fatty acids associated with regulation of inflammation, called linoleate metabolites, were brought to up to a beneficial level after a spinach diet.

"We believe eating spinach can also be protective for people who do not have familial adenomatous polyposis," said principal investigator Roderick Dashwood.

Dashwood's lab previously noticed the benefits of spinach in a carcinogen-induced model of colorectal cancer that mimics sporadic cases. In that model, spinach was very effective in preventing polyps, which spurred the team to see how spinach might work in colon cancer driven by genetics.

"My bias was to focus on the chlorophyll story because of my long history examining anti-cancer effects of chlorophyll," Dashwood said. "But it turned out the multi-omics approach prompted other ideas. When we looked at the metabolomic data, there was no chlorophyll. It was actually fatty acids and linoleic acid derivatives that were causing the beneficial effects."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
Navigation: use the links below to view more comments.
first 1-2021-24 next last
The researcher thought it might be a function of chlorophyll, but, strangely, it’s due to what the spinach appears to help make occur in the gut with various simple fats. Strange outcome from an item that has virtually no fat on its own. However, gut bacteria can create these simple fats from various fibers, which we then absorb.
1 posted on 09/23/2021 12:05:01 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: ConservativeMind

2 posted on 09/23/2021 12:08:19 PM PDT by BigEdLB (All animals are equal, but some are more equal than others-George Orwell)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Collard Greens are better...


3 posted on 09/23/2021 12:09:29 PM PDT by devane617 (RUN FOR LOCAL ELECTED OFFICE! COUNCIL,SCHOOL BOARD, ETC.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Interesting.


4 posted on 09/23/2021 12:12:46 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

But....I’m thinking they tell kidney patients to NOT eat spinach because something in it helps cause kidney stones?

Not anti-spinach (got some in my fridge right now!). But seems like even healthy things can be unhealthy to the right (wrong?) people.


5 posted on 09/23/2021 12:15:29 PM PDT by Spirit of Liberty (~Truth does not mind being questioned. A lie does not like being challenged.~)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BigEdLB

Research....some people on certain medications with too much potassium or too low potassium can be a problem. Foods and medications are very connected. Just sayin’...research....


6 posted on 09/23/2021 12:16:33 PM PDT by TribalPrincess2U
[ Post Reply | Private Reply | To 2 | View Replies]

To: BigEdLB

7 posted on 09/23/2021 12:18:31 PM PDT by Vaquero (Don't pick a fight with an old guy. If he is too old to fight, he'll just kill you. )
[ Post Reply | Private Reply | To 2 | View Replies]

To: Spirit of Liberty

There can be issues:

https://www.livestrong.com/article/529555-what-are-the-effects-of-too-much-spinach/

I understand having a calcium source with the spinach causes the oxalate to bind within the gut, rather than in the bloodstream, so have cheese, milk, or a supplement with your spinach. Also, as the link above states, theow out the remaining liquid from cooking spinach.


8 posted on 09/23/2021 12:20:30 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: ConservativeMind

Curcumin also.


9 posted on 09/23/2021 12:22:37 PM PDT by packagingguy (Kit)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Spirit of Liberty

Oxalic acid is high in spinach. Kidney stone prone should avoid large amounts.


10 posted on 09/23/2021 12:22:37 PM PDT by KC Burke (If all the world is a stage, I would like to request my lighting be adjusted.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: ConservativeMind

11 posted on 09/23/2021 12:24:51 PM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

It fights to the finish


12 posted on 09/23/2021 12:34:57 PM PDT by A_Former_Democrat (#LeaveTheGOP. Pass it on Liberty Valance Time. The point of a gun is the only law they understan)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

never hurt Popeye


13 posted on 09/23/2021 12:38:04 PM PDT by faithhopecharity (Politicians are not born, they are excreted. Marcus Tullius Cicero (106 to 43 BCE))
[ Post Reply | Private Reply | To 1 | View Replies]

To: TribalPrincess2U

I am a fan of spinach myself. Italian caneline, or Indian saag, and just a regular salad with vinaigrette are all good


14 posted on 09/23/2021 12:53:46 PM PDT by BigEdLB (All animals are equal, but some are more equal than others-George Orwell)
[ Post Reply | Private Reply | To 6 | View Replies]

To: ConservativeMind

I’ll take my chances with cancer.


15 posted on 09/23/2021 1:41:39 PM PDT by AlaskaErik (In time of peace, prepare for war.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

An ounce of spinach (28g) has 114% MDR vitamin K and 89% of vitamin A and only 6.5 calories.


16 posted on 09/23/2021 2:01:30 PM PDT by The Truth Will Make You Free
[ Post Reply | Private Reply | To 1 | View Replies]

To: KC Burke

“Oxalic acid is high in spinach. Kidney stone prone should avoid large amounts.”


Drink a lot of dihydrogen monoxide and it’ll get flushed out. That’s half of the problem with kidney disorders, is various substances not getting flushed out of your system due to dehydration.


17 posted on 09/23/2021 2:19:03 PM PDT by Ancesthntr ("The right to buy weapons is the right to be free." A. E. van Vogt, “The Weapon Shops of Isher”)
[ Post Reply | Private Reply | To 10 | View Replies]

To: The Truth Will Make You Free

Spinach should NOT be consumed regularly because it has toxic levels of oxalates, which are sharp crystals that bind with calcium to cause kidney stones, breast cancer, heart attacks from plaques, and many other health problems.


18 posted on 09/23/2021 2:31:37 PM PDT by WLusvardi
[ Post Reply | Private Reply | To 16 | View Replies]

To: Ancesthntr

That’s somewhat hard for me as I no longer have a stomach.


19 posted on 09/23/2021 3:24:07 PM PDT by KC Burke (If all the world is a stage, I would like to request my lighting be adjusted.)
[ Post Reply | Private Reply | To 17 | View Replies]

To: KC Burke

I am very sorry to hear that. Obviously, consult with your doctors, but also do a lot of reading for yourself. A source that I have learned a lot from is Life Extension Foundation https://www.lifeextension.com/ Specifically, they have a bunch of health protocols which describe a wide variety of diseases and conditions, what causes them, what conventional treatments are, what some novel or potential upcoming treatments may be available, and how to help that condition with nutrition. https://www.lifeextension.com/protocols

Best of health and luck to you.


20 posted on 09/23/2021 5:20:38 PM PDT by Ancesthntr ("The right to buy weapons is the right to be free." A. E. van Vogt, “The Weapon Shops of Isher”)
[ Post Reply | Private Reply | To 19 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-24 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson