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Insulin resistance doubles risk of major depressive disorder, study finds (carbs/lack of exercise and sleep issue)
Medical XPress / Stanford University Medical Center / American Journal of Psychiatry ^ | Sept. 23, 2021 | Natalie Rasgon, MD, Ph.D. et al.

Posted on 09/23/2021 11:52:52 AM PDT by ConservativeMind

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing major depressive disorder.

Upward of 1 in 5 Americans experiences major depressive disorder sometime during their lives. Symptoms include unremitting sadness, despair, sluggishness, sleep disturbances and loss of appetite.

But insulin resistance is preventable: It can be reduced or eliminated by diet, exercise and, if need be, drugs.

A common but silent condition

Studies have confirmed that at least 1 in 3 of us is walking around with insulin resistance—often without knowing it. The condition does not arise from a deficiency in the pancreas's ability to secrete insulin into the bloodstream, as occurs in Type 1 diabetes, but because of the decreased ability of cells throughout the body to heed this hormone's command.

But an increasing proportion of the world's population is insulin-resistant: For various reasons—including excessive caloric intake, lack of exercise, stress and not getting enough sleep—their insulin receptors fail to bind to insulin properly. Eventually, their blood-sugar levels become chronically high.

…The team measured three proxies of insulin resistance: fasting blood glucose levels, waist circumference, and the ratio of circulating triglyceride levels to those of circulating high-density lipoprotein—or HDL, known as "good" cholesterol.

By all three measures, the answer was yes: They discovered that a moderate increase in insulin resistance, as measured by the triglyceride-to-HDL ratio, was linked to an 89% increase in the rate of new cases of major depressive disorder. Similarly, every 5-centimeter increase in abdominal fat was related to an 11% higher rate of depression, and an increase in fasting plasma glucose of 18 milligrams per deciliter of blood was associated with a 37% higher rate of depression.

…The bottom line: Insulin resistance is a strong risk factor for serious problems, including not only Type 2 diabetes but depression.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: diabetes; insulin; nutrition
If you know someone hurting in such ways, see if you can give them a nudge toward healthier practices.

If it’s you and you don’t yet have health issues outside of insulin resistance, please consider reversing your situation now.

1 posted on 09/23/2021 11:52:52 AM PDT by ConservativeMind
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To: ConservativeMind

Given the VAST lies gushing out of the medical/government complex regarding COVID, why should I believe ANY medical study? EVER AGAIN?


2 posted on 09/23/2021 11:55:36 AM PDT by backwoods-engineer (But what do I know? I'm just a backwoods engineer.)
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To: ConservativeMind

BTW, did you read Cass Sunstein’s book, or are you just a closet communist?


3 posted on 09/23/2021 11:56:10 AM PDT by backwoods-engineer (But what do I know? I'm just a backwoods engineer.)
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To: ConservativeMind

Thanks for posting. Good info.


4 posted on 09/23/2021 12:02:22 PM PDT by vivenne ( )
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To: backwoods-engineer

Sorry about that. Yes, feel free to eat as many carbs as you’d like.


5 posted on 09/23/2021 12:07:40 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: backwoods-engineer; ConservativeMind

If you researched it, I think you’d find the healthcare/nutrition establishment don’t actually endorse what this study found. This is more or less a dissident study.


6 posted on 09/23/2021 12:17:31 PM PDT by nickcarraway
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To: backwoods-engineer

This is worth a shot.

Coworker had sky high A1C. Went low carb, and feels great. Same with me. Eating more protein means I eat LESS calories.


7 posted on 09/23/2021 12:25:48 PM PDT by redgolum (If this is civilization, I will be the barbarian. )
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To: nickcarraway
Insulin resistance has never been found to be beneficial to depressive disorder, so I'm not sure I understand how this could be terribly wrongheaded.

For that matter, a dietician a relative hired for newly discovered, serious Type 2 diabetes diagnosis prescribed an all carb diet, with a lot of cans of a shake that was simply flavored maltodextrin. Maltodextrin is 100 on the Glycemic Index, while table sugar is in the 70s. This, for a disease that is from too much blood sugar. My relative paid her over $10,000 for the special meal plan, destined to kill.

I gave her the facts that her expensive “medical professional” failed to know, and, within three months, she threw out the dietician’s incredibly stupid meal plan.

So, can you again describe why I should respect the default advice of the “healthcare/nutrition establishment?”

8 posted on 09/23/2021 12:28:53 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Drives me nuts how many solid patriot types talk a good game but most of them couldn’t run a mile or carry their gear and weapons 10 miles if their lives depended on it.

I’d say 80% of that is because of mild obesity and IR


9 posted on 09/23/2021 12:33:40 PM PDT by Manuel OKelley
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To: backwoods-engineer

I read studies like this. To my surprise, they are a good source of information. There are many studies and usually a false study will stand out compared to others. I think the data reported is usually correct. The conclusion might be propaganda. You can read the data and often reach the opposite conclusion from the author.


10 posted on 09/23/2021 12:33:59 PM PDT by TTFX ( )
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To: ConservativeMind

Sounds like it’s a disease targeting obese people. I’ve been seeing advertising a weight loss program for people who are insulin resistant implying they are that way because they are obese.


11 posted on 09/23/2021 2:20:54 PM PDT by antidemoncrat (somRead more at: https://economicti)
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To: ConservativeMind

Carbs are an issue if you don’t get up off your fat ass and move.

Otherwise, not so much.


12 posted on 09/23/2021 3:07:43 PM PDT by Mariner (War criminal #18)
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To: redgolum

“Eating more protein means I eat LESS calories.”

Now take the next step and get off your ass and move.


13 posted on 09/23/2021 3:10:20 PM PDT by Mariner (War criminal #18)
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To: Mariner

LOL. Already doing that. Walking 5 miles or so a day.

Walk. Not running. Knees are shot so that isn’t something I can do


14 posted on 09/23/2021 3:12:35 PM PDT by redgolum (If this is civilization, I will be the barbarian. )
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To: redgolum

Walking is better.


15 posted on 09/23/2021 3:13:51 PM PDT by Mariner (War criminal #18)
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To: Mariner

I agree.


16 posted on 09/23/2021 3:52:14 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: redgolum

On what way are your knees “shot?”


17 posted on 09/23/2021 3:52:56 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

No cartilage in my right knee.

Damage to my left.

Lot’s of injuries in my youth that resulted in me being able to know when rain is coming.

No drugs, yet, but my doc says I should expect my first new set of knees in my 50’s


18 posted on 09/24/2021 6:34:49 AM PDT by redgolum (If this is civilization, I will be the barbarian. )
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