Posted on 09/20/2021 12:11:34 AM PDT by blueplum
FDA expected to issue full emergency authorization for periodic antibody injections, or PrEP, to complement vaccinations
A proud sports mom, Shantay Brown longs to pack into a crowded stadium for her son’s Ohio State football games and scream her face off over the action on the field.
But as with so many other simple pleasures in the age of Covid-19, nothing is that simple for Brown. The 47-year-old Missouri resident takes immunosuppressant medication for lupus. Consequently, her body has mounted virtually no antibody response to the coronavirus vaccine – leaving her in persistent peril....
...In August, the FDA granted further emergency authorization to Regeneron’s cocktail for use as post-exposure prophylaxis, or PEP. ...Regeneron is in talks with the FDA about securing emergency authorization for Regen-Cov as PrEP. The protocol would probably entail monthly injections; the cocktail’s half-life is approximately that long....
...On 20 August, AstraZeneca announced preliminary, non-peer-reviewed results from an advanced trial of its cocktail as PrEP ...
(Excerpt) Read more at theguardian.com ...
Points to pull out: Regeneron at 81% for four weeks, half-life of four weeks; AstraZeneca at 77% and AZ's product is an injection rather than an infusion
Plaquenil is the preferred medication for Lupus.
If the media is pumping it, you can be sure a) there is a cheaper alternative medicine that is quite effective but has the downside of not feeding the pharma industry billion$, and b) the cheaper alternative medicine would destroy the effects of COVID so quickly that there would be no sense of a pandemic, hence destroying the pretense that the Deep State / pharma / Commie axis is using to push tyranny under the guise of an “emergency”.
Plaquenil, also known as hydroxychloroquine.
(Which ofc is why it was dicovered as a treatment in the first place - all the Lupus sufferers being immune to Covid)
Proceed with caution. The Biden Regime is intent on harming and killing Americans and they haven’t suddenly developed compassion for the immunocompromised.
lupus folks are NOT immune from covid, who told you that? But it is true the older and those with more than one other problem were more likely to have worse outcomes
In one study:
“early 60% of those with COVID-19 and lupus became sick enough to be hospitalized, and 10% were admitted to the intensive care unit.about 10% died.
In a second study:
of 102 infected patients, “26% of study subjects were hospitalized. About 4% died.”
Mixed feelings. Glad to have this being pushed, worried about overuse and the dilution of effect.
Why are you towing the democrat/media/big pharma/Faux-xi line?
hey Ransomnote
something you might find interesting - in a paper on a rare mutation found in about 0.5% European pop, TBK1 and TNFRSF13B mutations.. may cause an untuned IFN type I response,
and this paragraph, prednisolone vs methotrexate, something for people to discuss with their doctors:
“COVID-19 disease progression may have been exacerbated by the child’s preexisting unclassified autoinflammatory disease and treatment with prednisolone and methotrexate. A recent study analyzed 3729 patients with inflammatory rheumatic diseases28, and found that the use of high dose glucocorticoids (≥10 mg/day; odds ratio (OR) 1.69) and high disease activity (OR 1.87) were associated with a higher probability of death secondary to COVID-19. In contrast, methotrexate monotherapy was associated with a lower probability of death compared to the absence of a disease-modifying anti-rheumatic drug (DMARD) treatment (OR 0.47). Therefore, the child’s prednisolone treatment (0.16 mg/kg per day) in particular may have promoted the severe COVID-19 disease course. However, the referenced study involved adult patients, and the issue of whether the findings can be generalized to pediatric populations remains unclear.
https://www.nature.com/articles/s41525-021-00220-w
bump, thanks
I’m immune suppressed post-transplant, and I had COVID. Not severely to the point where I needed hospitalization, but I definitely had it. After learning the low efficacy of masks, I stopped using them and have been going about my business as normal. I don’t need to be, “freed.” Poor title choice on the author’s part.
I’m pretty lucky to not have long-hauler symptoms like one of my friends, who is ordinarily very healthy, so it’s interesting to hear about treatments other than, “vaxx!”
Plaquinil is HCQ. My sister was on it for years. She has Lupus and told me you can’t take the vaccine if you have an immunosuppresent condition. Not that she would take it anyway.
the better question is, what are the motives behind the pushback to informing immunocompromised of possible medical treatments to rectify zero antibody production?
Perhaps we should rely on the gamers or interior decorators on twitter to develop medications instead of researchers employed by pharmaceutical companies, eh?
LOL why are you even here? Are you paid by one of those companies? Which one is it? Moderna? Pfizer? J&J? AstraZeneca?
You’re shilling real hard for companies that made a hell of a lot of money this year by poisoning and killing people.
Do you get your information from CNN? ABC? NBC? MSNBC? From Faux-xi himself?
Have you purposefully not looked at any of the resources ransom posts? They’re a treasure trove of information on just how bad these death jabs are. There are also doctors going to school board meetings to spread the truth on just how bad these things are, and what the ramifications are to accept the death jab.
why am i here? LOL I am a child of God - why are you here? Did you think FR is a dedicated anti-vax website where the ‘vax-woke’ viewpoint is the only one allowed?
Do you know that over 60% of Republicans are vaccinated another 20% are partly or planning to, and a larger percentage are favorable towards monoclonal therapies? That 57% of Evangelicals, 80% of Catholics are vaccinated, with more men vaccinated than women? That Conservatives above lower income levels are also majority vaccinated and have always supported vaccinations, for kids, pets and livestock? Are more apt to take advantage of medical treatments made available to them? And are more apt to read reputable studies and challenge manipulated narratives that misrepresents data instead of blindly promoting internet gurus selling vitamins and books??
The question becomes, why does that bother you, or anyone for that matter?
Now, do you have any discussion about the subject matter or do you want to continue to play cancel culture, fraulein wasted?
Again, do you deliberately avoid all the great research ransom posts from the people actually treating it, rather than those writing articles behind a desk that haven’t done anything this whole time? How about the work Dr Zelenko is doing? He’s personally helped thousands, and his treatments have probably saved many more around the world.
But you continue to push the democrat/media/China/big pharma/Faux-xi narrative. Are you pulling these numbers from the air?
lupus folks are NOT immune from covid, who told you that? But it is true the older and those with more than one other problem were more likely to have worse outcomes
In one study:
“early 60% of those with COVID-19 and lupus became sick enough to be hospitalized, and 10% were admitted to the intensive care unit.about 10% died.
In a second study:
of 102 infected patients, “26% of study subjects were hospitalized. About 4% died.”
~~~~~~~~~~~~~~~~~~~~
We don’t have a valid test for Covid so we don’t know what people are dying of. Sadly, the weaponized medical establishment would not want those with Lupus taking HCQ to live so it’s possible they were targeted for medical elimination. My hope is that you simply have posted fake pharma industry data as usual.
https://www.health.harvard.edu/blog/does-lupus-or-arthritis-affect-your-prognosis-if-you-get-covid-19-2020110921230
In one study:
“early 60% of those with COVID-19 and lupus became sick enough to be hospitalized, and 10% were admitted to the intensive care unit.about 10% died.
In a second study:
of 102 infected patients, “26% of study subjects were hospitalized. About 4% died.”
~~~~~~~~~~~~~~~~~~~~
What a mess that first study is. No wonder you quote it. I'm not going to bother to read the second.
Based on the uniform conduct of the CDC driven medical establishment, and the use of the FAKE PCR test, no one knows what actute respiratory illness(es) those patients actually had, and they never recevied safe, effective, appropriate care.
You failed to mention the hospitalized had co-morbidities like cancer, COPD, Asthma, Diabetes, heart failure etc.
The man in this tweet spoke publicly about his horror when he realized the hospital he worked for was euthanizing patients rathter than treating them. I think the 'study' you cited may have utilized that evil practice as well.
According to him, the hospital would deny patients effective medicine and prevent patients from even one minute of visiting with family ("No! No! Wait until their blood ox is over 90!) and break them psychologically by telling them this isolation and ventilator was permanent, there would be no recovery for them. The patients broke and called in palliative care to give them morphone as they were taken off the vent and died.
The following quote from your link indicates that tactic was likely at work in 'the study' or the hospital in the study too.
"Four patients (16.7%) died of hypoxemic respiratory failure from COVID-19; of note, 3 of these patients had changed their code status to do not resuscitate/do not intubate (DNR/DNI), and 1 underwent intubation and renal replacement therapy during ICU admission. The average age of the deceased patients was 72 ± 6.9 years, and the majority (75%) were nonwhite, female, and experiencing at least 1 comorbidity (uncontrolled hypertension and LN were the most common, in 75% and 50% of patients, respectively). All 4 patients who died were receiving HCQ, 2 were receiving prednisone (≤7.5 mg/day), and 1 each were receiving cyclophosphamide and MMF. Additional characteristics of the admitted patients, including laboratory and chest imaging results, are provided in Table 2."
In bold text above, the patients who died were only on HCQ and not with AZithromycin. The deep state medical establishment refuses to use both together, as is critical, and all dosing is either too high, too low, or too late. NONE of the 24 hospitalized patients received Azithromycin and it's likely the 18 who did were given the wrong dose, intentionally. Haven't we already seen nationwide attempts to keep people from accessing drugs that work?
Those patients had other medications and having to take immunosuppressents at the same time they were ill with an unidentified respiratory illness, and trying to fight off organized medicine was an extraordinary challenge.
The data you quote is compromised by Faucists. Harvard and the Lancet have been caught singing along with the Wuhan choir before. They labor to destroy lives.
hey ransomnote.
You failed to mention the hospitalized had co-morbidities like cancer, COPD, Asthma, Diabetes, heart failure etc.
no I did - right before the link ‘older and those with more than one..blah blah
I can’t really argue ‘fake pcr test’ unless we’re talking specifics. I’m partial to the Curative PCR, which erred on the negative side, rather than the positive side. (I’d rather have a false negative delaying two days than a false positive making me freak out). But with the introduction of Abbott Labs 3-in-1 test, I guess the single PCRs will cycle out of use?
from even one minute of visiting with family
I read somewhere that covid in hospital patients is gone by 20 days or couldn’t be PCR’d in 20 days, something like that. But not all ICU or isolation patients go in at the same time - not all, you group, 20 days. So there’s still a risk of cross-contamination from visitor to patient and ward patient to visitor. You’ve seen the photos of wards where the tubing and cords from equipment goes out the ward door and the staff are on the other side - that is, nobody in the room but patients. I know that the nurses will help with facetime or zoom or whatever the chat app is, so that families can talk to their loved ones. I can’t imagine being family in that position. And it’s not like the med staff can’t hear the anguish and it not affect them.
HCQ and dying - well, it’s been known for a while that our beloved HCQ tanked in studies including this one of immunocompromised. RIP little buddy you tried.
Regarding treatment medications: here’s the NIH guidelines. Doctors may or may not add their favorite to the lineup but they do give you medication and some heavy hitting stuff at that. Mostly its’ to control the inflammation caused by the virus and/or deal with stacked rBCs. But what you need most is oxygen:
https://www.covid19treatmentguidelines.nih.gov/management/clinical-management/hospitalized-adults—therapeutic-management/
changing advance directives - It’s not something medical staff can do. Caveat: crisis standard of care allows triage and triage will consider pre-existing directives in an emergency case by case. I think if someone is suffocating or in extreme pain, and it’s been weeks, a patient may decide to throw the towel in by creating or updating their Advance Directive (which everyone of every age should have btw). But even then, if there’s a chance of them getting better, it’s not going to apply. No assisted suicide on demand going on. In the absence of family or a directive, covid patients have lasted for months and months. There’s no expiration date on the soul of your foot.
re: Az - one of the heaviest antibacterials we have rx, but not recommended by the NIH - showed some antiviral properties in testtubes but requires 14 days for serum levels making it unsuitable for treating serious cases who may not have 14 days to spare, blah blah. UC San Fran 7/21 says it’s comparable to a placebo, and may increase risk of infection. Another little buddy back on the shelf:
https://www.ucsf.edu/news/2021/07/421051/common-covid-19-antibiotic-no-more-effective-placebo
I’d disagree the data here is ‘faucist’. Fauci may be a flake but science done right isn’t.
If something can help protect the immunocompromised, in this case, artificial ‘antibody injections’, that has intrinsic good that supercedes politics. Peer review is also layman review. Papers are meant to be dissected and discussed, not just criticizing good ones, but the bad ones too.
Thanks for the discussion. As always, the mic is yours.
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