Posted on 09/14/2021 8:28:18 AM PDT by SeekAndFind
The discovery, achieved by a team of researchers at the University of Georgia, provides new hope of a variable therapeutic that is proficient in defeating the deadly disease that has caused over four million deaths globally. The team discovered that Probenecid – a gout medication – displayed broad antiviral properties that make it a prime candidate to fight SARS-CoV-2 infection. The gout medication may also aid in treating common and deadly respiratory viruses such as RSV and flu.
Probenecid is approved by the FDA and is widely available throughout parts of the world, demonstrates minimal side effects and has been implemented on the market for over 40 years.
The team’s research is published in Nature’s Scientific Reports.
Ralph Tripp, the lead author of the study and GRA Eminent Scholar of Vaccine and Therapeutic Studies in UGA’s College of Veterinary Medicine, said: “There’s really nothing out there to safely fight these viruses. This antiviral works for all RNA respiratory viruses we tested, including SARS-CoV-2. RSV, coronavirus, and flu all circulate in the same season. The bottom line is you can potentially reduce infection and disease using this one oral drug.”
A virus works by co-opting an individual’s cells, where it then replicates and produces more of the virus; however, probenecid obstructs this replication process, stopping the virus from infecting the person’s cells.
During clinical development at the TrippBio, Tripp identified that the gout medication also works as a prophylactic prior to virus exposure and a post-exposure treatment in animal models against SARS-CoV-2 and flu. Additionally, probenecid was shown to be effective in combatting the RSV in vitro, with in vivo studies currently in progress.
The gout medication would predominantly be used after contracting the virus but could also potentially be implemented to prevent people with known exposures from getting sick due to its prophylactic qualities.
The treatments traditionally employed to aid seriously ill COVID-19 patients are remdesivir and monoclonal antibodies, which can only be administered through IV and by the time they are required, it is usually too late for the patient.
Tripp said: “These treatments have seen some effectiveness against SARS-CoV-2, but they’re very expensive and very hard to come by. In reality, there are only a handful of options that can actually be used because of the cost, restricted IV usage, and lack of access. That’s not very useful to the world.”
Nevertheless, probenecid is widely available, meaning that primary care physicians would be able to prescribe the gout medication for a patient to pick up at their local pharmacy. This strategy of repurposing drugs for other uses is common; for example, remdesivir was initially used to fight the Ebola virus and was employed later to battle COVID-19 after demonstrating its effectiveness.
Furthermore, probenecid may potentially enhance the efficacy of other treatments and is already used to boost the potency of an array of antibiotics, meaning it could work in conjunction with other COVID-19 treatments. The researchers are now working to distinguish the most optimal dose of probenecid, with clinical trials set to begin within the year.
“SARS-CoV-2, RSV and flu have a huge impact on health systems throughout the world,” Tripp commented. “Probenecid has a potent antiviral effect against these viruses, and it works safely.”
Is that horse gout or human gout?
CNN says it is pig gout paste.
Well my dumbass doctor told me there was no medication that would work for gout a couple years ago. Smh.
RE: Is that horse gout or human gout?
OK, I understand the sarcastic reference to Ivermectin, but the article makes it clear that Probenecid is prescribed for HUMANS and can be bought at your local pharmacy.
RE: Well my dumbass doctor told me there was no medication that would work for gout a couple years ago
Is he still your doctor?
‘You aren’t Henry VIII, y’all’
Another option put out there by reputable academic institutions being put out there in the face of the Fauci “vaccine or bust” plan.
We are headed towards a period of deep anger towards our governmental institutions, media, and big pharma as more Americans realize that there were options that might have saved their loved one, but it did not benefit the power structure.
To make matters worse, the man most responsible for denying all therapeutics had a hand in funding the lab and experiments that created it in the first place.
Thou shalt mention no other means to combat COVID other than the vaccines.
Ivermectin is prescribed for humans and used to be easy to get from your local pharmacy.
If this drug works, I expect a similar clamp down. Can’t have any treatment cutting into Pfizer et al.’s profits.
Naa. No medication commonly in use will be accepted to treat Wuhan Flu. It must be a new, very expensive drug so the money can be spread around. Very, Very Expensive in order to have enough to spread amongst the elected officials, the regulators, a few influential media figures and still have an adequate profit left over for the big pharmaceuticals.
An existing inexpensive medication just ain’t gonna cut it.
Big Pharma won’t let it be utilized.
That’s not good. I’ve been on allopurinol for gout since my first attack, back in 2012 I think. Doc needs to hit the books.
Looks like everything under the sun works now, except Ivermectin. Must be the wild goose chase strategy.
And by Big pharma, you obviously mean CONgress and Josef Stolen, of course!
I just used black cherry juice and it worked great.
RE: Looks like everything under the sun works now, except Ivermectin.
Hydroychloroquine works too. Unfortunately, Trump said good things about it.
Damn, every day we get a new treatment. Appears that about every medication out there can treat the china flu except the gov’t prescribed shots.
OK, I understand the sarcastic reference to Ivermectin, but the article makes it clear that Probenecid is prescribed for HUMANS and can be bought at your local pharmacy.
= = =
Yes, but I need some for my horse, as the horse paste is out of stock.
Mitagare ( 6 mg) is the best gout medication IMO. Works quickly.
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