Posted on 09/13/2021 9:24:22 PM PDT by ConservativeMind
As we age, our bones become thinner, we suffer fractures more often, and bone-diseases such as osteoporosis are more likely to occur. One responsible mechanism involves the impaired function of the bone-marrow stem cells, which are required for the maintenance of bone integrity. They were able to reverse these changes in isolated stem cells by adding acetate.
The epigenetic changes of aging stem cells
"We wanted to know why these stem cells produce less material for the development and maintenance of bones as we age, causing more and more fat to accumulate in the bone marrow. To do this, we compared the epigenome of stem cells from young and old mice," explains Andromachi Pouikli, first author of the study. "We could see that the epigenome changes significantly with age. Genes that are important for bone production are particularly affected."
Rejuvenation of the epigenome
The researchers then investigated whether the epigenome of stem cells could be rejuvenated. To do this, they treated isolated stem cells from mouse bone marrow with a nutrient solution which contained sodium acetate. The cell converts the acetate into a building block that enzymes can attach to histones to increase access to genes, thereby boosting their activity. "This treatment impressively caused the epigenome to rejuvenate, improving stem cell activity and leading to higher production of bone cells," Pouikli said.
A new therapeutic approach against osteoporosis?
"Sodium acetate is also available as a food additive, however, it is not advisable to use it in this form against osteoporosis, as our observed effect is very specific to certain cells. However, we still need to investigate in more detail the effects on the whole organism in order to exclude possible risks and side effects," explains Peter Tessarz, who led the study.
(Excerpt) Read more at medicalxpress.com ...
“Chemical suppliers and manufacturers typically produce sodium acetate by reacting acetic acid (vinegar) with sodium hydroxide or sodium carbonate; it can also be produced without any special equipment by simply mixing vinegar and baking soda.”
https://healthfully.com/dangers-sodium-acetate-6573450.html
Later.
If you add coloring you can play volcano.
So it may be best to take it, say, twice a week, and play it safe?
Not to worry. Jeff Bezos will get to the bottom of it. He quit Amazon to focus on solving aging and death.
He should focus on balding.
So just brush your teeth with baking soda and balsamic vinegar.
bump for reference.
>> He quit Amazon to focus on solving aging and death.
Idiot.
Paint. Write. Compose. Love. Hunt. Fish.
Thanks for posting
Sodium acetate can be most safely and easily made by combining a little sodium bicarbonate with vinegar.
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I didn’t see anything that referred to proportions. How would you guess proportions? a teaspoon of baking soda, two tablespoons of apple cider vinegar and mix with water, (with stevia) and maybe lemon juice twice a week?
I’d say 1/4 of a teaspoon of baking soda should not be a problem, and it’s encouraged for whole body inflammation:
https://freerepublic.com/focus/f-chat/3792811/posts
Do you see doing this daily or only once or twice a week.
I’d see doing it daily as being fine.
I’ve been taking this as 1/4 teaspoon baking soda and enough vinegar to react out all of that baking soda. That produces sodium acetate and water and some CO2 that bubbles out, as I understand it. I haven’t noticed an issue, but came across this information that shows that with added heat (unknown how much), the sodium acetate and included water breaks back into acetate plus a small amount of NaOH. NaOH is lye.
https://www.quora.com/What-happens-when-sodium-acetate-dissolves-in-water
I know vinegar and baking soda is a good substitute for baking powder in recipes and sodium acetate is sometimes added to potato chips for flavor, but I think I’ll wait until I can find out something more to restart my sodium acetate use.
I just wanted to give each of you a brief note on it.
Is that how it works in your stomach?
Yes, stomach acid and bicarb
I had saved your earlier post on that but had done nothing.
Thanks for the update
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