In Vitro Efficacy of a Povidone-Iodine Nasal Antiseptic for Rapid Inactivation of SARS-CoV-2

NIH - PubMed.gov ^ | November 1, 2020 | Samantha Frank, Seth M Brown, et al

[Qiviut]

Abstract

Importance: Research is needed to demonstrate the efficacy of nasal povidone-iodine (PVP-I) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Objective: To evaluate the in vitro efficacy of PVP-I nasal antiseptic for the inactivation of SARS-CoV-2 at clinically significant contact times of 15 and 30 seconds.

Interventions: The SARS-CoV-2, USA-WA1/2020 strain, virus stock was tested against nasal antiseptic solutions consisting of aqueous PVP-I as the sole active ingredient. Povidone-iodine was tested at diluted concentrations of 0.5%, 1.25%, and 2.5% and compared with controls. The test solutions and virus were incubated at mean (SD) room temperature of 22 (2) °C for time periods of 15 and 30 seconds.

Design and setting: This controlled in vitro laboratory research study used 3 different concentrations of study solution and ethanol, 70%, as a positive control on test media infected with SARS-CoV-2. Test media without virus were added to 2 tubes of the compounds to serve as toxicity and neutralization controls. Ethanol, 70%, was tested in parallel as a positive control and water only as a negative control.

Main outcomes and measures: The primary study outcome measurement was the log reduction value after 15 seconds and 30 seconds of given treatment. Surviving virus from each sample was quantified by standard end point dilution assay, and the log reduction value of each compound was compared with the negative (water) control.

Results: Povidone-iodine nasal antiseptics at concentrations (0.5%, 1.25%, and 2.5%) completely inactivated SARS-CoV-2 within 15 seconds of contact as measured by log reduction value of greater than 3 log10 of the 50% cell culture infectious dose of the virus. The ethanol, 70%, positive control did not completely inactivate SARS-CoV-2 after 15 seconds of contact. The nasal antiseptics tested performed better than the standard positive control routinely used for in vitro assessment of anti-SARS-CoV-2 agents at a contact time of 15 seconds. No cytotoxic effects on cells were observed after contact with each of the nasal antiseptics tested.

Conclusions and relevance: Povidone-iodine nasal antiseptic solutions at concentrations as low as 0.5% rapidly inactivate SARS-CoV-2 at contact times as short as 15 seconds. Intranasal use of PVP-I has demonstrated safety at concentrations of 1.25% and below and may play an adjunctive role in mitigating viral transmission beyond personal protective equipment.

[Qiviut]

I bought a bottle of 10% at CVS & diluted it.

[Coffee_drinker]

I love hearing about these “old” remedies coming back into the news. They don’t make PHARMA any money but likewise they don’t cost the consumer very much money either and that’s who is the most affected by cost.

Our best interest should be the driving motivation..

CD

[Bell Bouy II]

thanks was wondering too about a steamed solution

[wetgundog]

Using 10% Povidine Iodine 4:1 gives 2.5%; 5:1 gives 2%, 20:1 gives .5% The large number being clean water.

[Bell Bouy II]

“co-workers”
No vax no coworkers all got fired

[Bell Bouy II]

Thanks

[corkoman]

Are you OK? Having a bad day?

[fullchroma]

Very good info at this link. Be sure to watch the short how-to video.

https://krcrtv.com/news/local/redding-doctor-says-he-may-have-a-solution-to-prevent-transmission-of-covid-19

[Qiviut]

Great link - thank you!!

[Jane Long]

Are you okay?

You’re the one who incorrectly complained about the subject of this thread/article, seemingly without reading the article.

Hope your day improves ;-)

[ryderann]

Ck this out https://www.carragelose.com/en

If you want to try it, I got mine here:

https://www.ebay.com/itm/203479598136?ssPageName=STRK%3AMEBIDX%3AIT&_trksid=p2060353.m2749.l2649

[BobL]

Let me guess: They’re calling it Ivernosen.

[Jane Long]

The Dr Peter McCullough interview (was just posted, today), is excellent.

McCullough goes through the timeline of these shots, backed with numbers/studies and reasons why they should have been stopped, months ago (based on other vaccines that had ill effects, that were stopped after ONLY 150 DEATHS), and, why vaccines have NEVER been recommended to pregnant women....until this horrid shot.

Talks about the “trance” that many docs are under, when it comes to these shots....

He is a waking medical encyclopedia....

https://articles.mercola.com/sites/articles/archive/2021/09/10/perspectives-on-the-pandemic-with-dr-peter-mccullough.aspx

STORY AT-A-GLANCE

Dr. Peter McCullough is an internist, cardiologist and epidemiologist who warns that COVID-19 vaccines not only are failing but are putting lives at risk
McCullough believes if the proper safety boards had been in place, the COVID-19 vaccine program would have been shut down in February 2021 based on safety and risk of death

By January 22, 2021, 186 deaths had been reported after COVID-19 vaccination — more than enough to reach the mortality signal of concern

In his practice, McCullough is seeing an array of neurologic syndromes in people who’ve been vaccinated, with symptoms including blindness, paralysis, difficulty swallowing, headaches, ringing in the ears, myocarditis and more

McCullough also mentions antigenic, or immune, escape, which he believes is driving the creation of COVID-19 variants and making the pandemic worse instead of better

Dr. Peter McCullough has an impressive list of credentials1 — he’s an internist, cardiologist, epidemiologist and a full professor of medicine at Texas A&M College of Medicine in Dallas and is the editor of two medical journals and published hundreds of studies in the literature.

He’s also among those brave and courageous persons speaking out about the dangers of COVID-19 jabs, and putting his medical license and future livelihood at risk by so doing.

[Jane Long]

From Dr McCullough's interview.....report from UK.....64% of CV deaths are of.....vaccinated....

[Qiviut]

The one I saw last night was Dr McM being interviewed by 3 New Zealand ladies. The interview was OUTSTANDING in the amount of info presented. How absolutely INSANE the CDC, Fauci, FDA, Illegitimate Joe, et al are and what the devastating ramifications are likely to be is made abundantly clear. I was left shaking my head wondering if I’m living in some alternate reality instead of what is supposed to be America.

Here is the link:

https://odysee.com/@voicesforfreedom:6/Dr-Peter-McCullough:b

You can skip the first 5 minutes or so. If you are super short of time, you could start listening at an hour in & get a good dose of info, but I would highly recommend the entire thing - just loaded with info. Sound is pretty good for the doc and he does a great job of explaining pretty much ‘everything’.

[logi_cal869]

Pfiverschnozen

[Qiviut]

LOL!

[Qiviut]

You can do it this way, too if you don’t want to mess with math! :-)

https://freerepublic.com/focus/chat/3993635/posts?page=28#28

[Faith65]

Thanks.
BFL

[Two Kids' Dad]

Will check it later. Thanks.