Posted on 09/02/2021 2:01:01 PM PDT by ConservativeMind
Viagra, used to treat sexual impotence, can strongly suppress abnormal heart rhythms known as arrythmias in sheep according to scientists.
In female sheep, the drug—also known as sildenafil—was able to suppress an arrythmia called Torsades de Pointes within 90 seconds by reducing the frequency of irregular heart rhythms caused by abnormal handling of calcium.
It also reduced the probability of Torsades de Pointes, which can lead to sudden cardiac death. However, the team believe the drug could treat other arrythmias as well.
Cardiac arrythmias often follow a heart attack, or result from heart disease. Though often benign , they can cause symptoms including palpitations, breathlessness, fainting and sometimes sudden death.
Treatments such as beta blockers and implantable defibrillators exist, though are not always effective.
Working on isolated sheep heart muscle cells known as myocytes, the research team were also able to measure their calcium stores- as well as their electrical properties.
Although calcium is a key driver of the heart's pumping action, its overload can be a root cause of arrythmias. Viagra was able to suppress the mechanism in the cell which causes calcium overload.
When a small amount calcium enters a myocyte, it triggers the Sarcoplasmic Reticulum (SR)—a calcium store—to release a larger quantity of calcium.
When there is heart disease, the SR can become overloaded with calcium which in turn makes the heart beat at the wrong time- when it is supposed to be resting between beats.
"In 2016, our study of patients with diabetes showed that incidental use of Viagra was linked with reduced heart attack risk and improved heart attack survival."
"In 2019, we found that Viagra can slow or even reverse the progression of heart failure in sheep and this work dramatically extends those important findings providing another tool with which to beat heart disease."
(Excerpt) Read more at medicalxpress.com ...
—”What if one takes it with cocaine, Jack Daniels, and a woman of the evening?”
Is this service available outside of Hollywood?
Is this the same as the hunter biden special?
Guess it would be better described as using hardening of the arteries to fight arrhythmia!!
You need a good stiff talking-to.
“My friend” prefers nose candy over rocks, as rocks are ghetto. I believe it’s available in Wilmington DE. In fact Hunter’s sister is probably down.
Yeah.. I remember the first time I tried a viagra. It got stuck in my throat and I ended up with a stiff neck....ha ha ha
Surprised my d o c gave me a prescription for this, and even more surprised my insurance covered it. It makes this old man feel like he’s 19 again, yippee!
Or all of our friends wearing masks day and night, when alone, on trails, in their cars.
Funny
Old Jewish guy in Florida buys a new pair of golf shoes. He loves them. He puts them on and asks his wife, “Do you see anything new?” She responds, “No”
He takes off all his clothes, except for the new shoes, and comes out again.
”Now do you see anything new?”
”No”
”What do you mean?”
”It’s hanging down now, it was hanging down yesterday, It was hanging down a month ago!”
”He’s looking at my new golf shoes!”
”You should have bought a hat!”
-pj
I wonder if it would be of any use in dogs with dilated cardiomyopathy?
They often have arrhythmias as well but I’m not sure if they’re the right kind, to benefit.
This study follows hard on
the heels of a study showing that E.D. is no big thing.
That is so funny on so many levels.
Shoot, a fella' could have a pretty good weekend in Vegas with all that stuff.
Thanks. Once in a while a zinger occurs to me.
Viagra is truly a wonder drug, for several reasons.
1) It has crashed the market for endangered animal parts for use in aphrodisiacs. In addition, it works on most mammals, even those species that are slow to breed, like giant pandas, strongly increasing their numbers.
2) As a pediatric drug for premature babies with underdeveloped cardiopulmonary systems. It opens up arteries, veins and capillaries, enhancing their chances for normal development.
3) As an adult drug for pulmonary hypertension (high pressure in the blood vessels leading to the lungs), congestive heart failure and diastolic dysfunction. Many other positive cardio effects are suspected.
4) It works against cold weather in Raynaud’s phenomenon, and altitude sickness.
No idea.
“Hillary Clinton — where boners go to die.”
(The one funny thing Jon Stewart’s writers had him say.)
It also happens to be effective on neuropathy of the feet, a condition I have . . . but insurance won’t cover it because of the, ahem, other reason. It costs less than a nickel a dose to manufacture. The best I can do is $1 per pill from a legitimate mail order pharmacy which requires a script and a 60 pill minimum. So I use it sparingly.
Well yeah. It was invented as heart medication. Then during the first human trials they found an interesting side effect.
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