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Smoking exposure during childhood may increase risk of rheumatoid arthritis (at least 75% higher, womb exposure and smoke after age 18 didn’t affect)
Medical XPress / Brigham and Women's Hospital / Arthritis Rheumatology ^ | Aug 18, 2021 | Yoshida K et al.

Posted on 08/23/2021 8:13:41 AM PDT by ConservativeMind

Passive exposure was broken down into three categories, including maternal smoking during pregnancy, parental smoking during childhood, and years lived with smokers since age 18. Even with personal smoking accounted for, passive exposure to parental smoking during childhood was found to increase risk of incident seropositive RA by 75-percent.

"There has been intense interest in mucosal lung inflammation from personal smoking as a site of RA pathogenesis," said senior author Jeffrey A. Sparks, MD. "But the majority of RA patients aren't smokers, so we wanted to look at another inhalant that might precede RA."

RA is an inflammatory disease characterized by arthritis at multiple joints and is associated with morbidity and mortality outcomes.

A 75-percent higher risk of RA was found in individuals who experienced passive childhood exposure to parental smoking. This risk increased in participants who themselves became active smokers. Over the median follow-up of 27.7 years, 532 women in the cohort developed confirmed incident RA cases—the majority (352) of which were seropositive (positive for RA autoantibodies). Maternal smoking during pregnancy and years lived with smokers beyond age 18 showed no significant association with incident RA risk.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: arthritis; ra; rheumatoidarthritis; smoking
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If you are like me, both parents smoked up a storm with multiple packs of cigarettes a day each. All we can do is work now to reduce inflammation sources and encourage general healthy living habits.
1 posted on 08/23/2021 8:13:41 AM PDT by ConservativeMind
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Comment #2 Removed by Moderator

To: ConservativeMind; NobleFree

Looks like the final notes on tobacco smoke are being written. Good thing RA is such a benign condition.
/

The same can’t be said of marijuana, with its effect on a growing brain.


3 posted on 08/23/2021 8:23:01 AM PDT by Does so (USA is run from 2446 Belmont Rd, NW, DC, (Kalorama). Why else the 9/11 deadline for Afghanistan?)
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To: ConservativeMind

4 posted on 08/23/2021 8:35:27 AM PDT by Daffynition (*Mega Dittoes and Mega Prayers* & :))
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To: Does so
It is fascinating to watch the ongoing demonization of tobacco while marijuana gets a free pass...

Neither are good for you, but the truth is somewhere in the middle on both.

Marijuana is more dangerous imho for a very simple reason--folks driving while using it are going to kill and injure others as well as themselves.
5 posted on 08/23/2021 8:51:01 AM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: ConservativeMind

My wife (age 80) has terrible arthritis and no one in her immediate or near family smoked. None of her siblings have arthritis. So far none of our 50+- something DNA pools and nieces and nephews have arthritis.

My mother and her siblings were depression/WWII teens/adults.

They all smoked until their late 20’s, and all of them had severe arthritis which got worse as they aged. They all lived to be 80 something.

So far my cousins,siblings, and I have avoided constant arthritis. We have wear and tear arthritis from basically sports injuries.

Cold weather sets that off, like this morning 55 degrees outside and 65 inside. Voltaren Gel dabbed on and rubbed into the key sore areas, works, when it gets too bad.


6 posted on 08/23/2021 9:09:10 AM PDT by Grampa Dave (If I wanted to live in Australia, Canada, New Zealand, UK, China, Cuba, Chicago/NYC! I'd move there )
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Comment #7 Removed by Moderator

To: Grampa Dave
So you both have osteo arthritis, it seems, from exercise.

I strongly encourage you to look into boron and an eggshell membrane supplement.

For the most severe osteo, patients were given 12 mg/day for two months.
By the 8th week, 75% had quit using pain medicines. By the 4th week, 50% of patients had lost all joint rigidity. More in pages 39-40 in this paper:

http://imjournal.com/openaccess/pizzorno144.pdf

The form of boron in the studies is the one in apples, calcium fructoborate. It is hard to find that form, but it is the sole boron in the only the following supplement:

https://smile.amazon.com/gp/aw/d/B07B6B4PWQ

One of those pills has 5.5 mg of boron, so two a day would get you 11 mg a day, which is close to the 12 mg a day in the study. The upper tolerable limit for boron is 20 mg a day, so you should do well with it. I take multiple borons getting me to 10+ mg a day.

Also, look into eggshell membrane. It naturally has standard stuff of common Move Free-type supplements, but it has a few other components that appear to go beyond any other similar supplement.

The one I take is this one:

https://smile.amazon.com/gp/aw/d/B00FS89FWI

8 posted on 08/23/2021 9:32:15 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Grampa Dave

According to the paper, some of the inflammatory activity of rheumatoid arthritis would be lessened with boron and it might help loosen things up for your wife, too.


9 posted on 08/23/2021 9:37:05 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Both of my parents smoked until I was age 13. RA is the bane of my existence. Ibuprofen daily. Turning 65 on Thursday. The ibuprofen is less effective as time passes.


10 posted on 08/23/2021 9:47:40 AM PDT by Myrddin
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To: ConservativeMind

I’m a Boomer, b1949. I myself never smoked. But both parents and virtually every adult I knew was a heavy smoker. Every place I worked until the early nineties was a smoking environment. Commercial airliners had ashtrays in the armrests. Everyone smoked. Everywhere. Movie theaters and churches were about the only exceptions.

I have rheumatoid arthritis. Fighting hard to old down inflammation.


11 posted on 08/23/2021 10:12:42 AM PDT by Chuckster (Friends don't let friends eat farmed fish)
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To: Does so
Good thing RA is such a benign condition.

Only someone who doesn't have it could say that. I would bet you don't even know anyone who has RA.

12 posted on 08/23/2021 10:14:54 AM PDT by Chuckster (Friends don't let friends eat farmed fish)
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To: ConservativeMind
"There has been intense interest in mucosal lung inflammation from personal smoking as a site of RA pathogenesis," said senior author Jeffrey A. Sparks, MD.

I have never heard of anyone who was interested in mucosal lung inflammation for any reason whatsoever, intense or otherwise.  

13 posted on 08/23/2021 10:27:23 AM PDT by higgmeister ( In the Shadow of The Big Chicken )
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To: Myrddin
RA is the bane of my existence. Ibuprofen daily. Turning 65 on Thursday. The ibuprofen is less effective as time passes.

That's where I was at 65. Suffering from gout, psoriasis and RA as well and walking with a cane.

Drastic dietary changes, (Basically eliminating all of my favorite food and drink), a little exercise and the introduction of CBD changed all that. At 72, I no longer take any pain meds. Just CBD. I miss the fried shrimp, beer and cheeseburgers. But I can walk a mile up to the post office without pain (Or a cane) and I can get a good nights sleep.

On the plus side, Living in Southeast Alaska, I can have all the salmon and wild game I want - AND - I'm healthy enough to go harvest it myself.

14 posted on 08/23/2021 10:31:00 AM PDT by Chuckster (Friends don't let friends eat farmed fish)
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To: Chuckster

“Looks like the final notes on tobacco smoke are being written. Good thing RA is such a benign condition.
/

The same can’t be said of marijuana, with its effect on a growing brain”.

The slash sign (/) was to indicate sarcasm (/sarcasm). I don’t know what the occasional pains I have in my wrists are, but I empathize with anyone suffering through the same pain.


15 posted on 08/23/2021 11:49:46 AM PDT by Does so (USA is run from 2446 Belmont Rd, NW, DC, (Kalorama). Why else the 9/11 deadline for Afghanistan?)
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To: Does so

Thanks for confirming that anti-pot zealotry and tobacco nazism walk hand in hand.


16 posted on 08/23/2021 8:32:48 PM PDT by NobleFree ("law is often but the tyrant's will, and always so when it violates the right of an individual")
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To: ConservativeMind

I never smoked, but have COPD. My mom smoked like a chimney while she was pregnant and for years until her death from lung cnacer.


17 posted on 08/24/2021 6:48:03 AM PDT by Mr.Unique (My boss wants me to sign up for a 401K. No way I'm running that far! )
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To: Mr.Unique

I had two VO2 Max tests done about 25 years ago when I was very physically fit.

It showed I was borderline COPD in my 20s.


18 posted on 08/24/2021 6:53:01 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Chuckster

What is your current diet, aside from tasty fresh meat?

You’ve made an incredible reversal and you help prove to others that an endemic health issue, isn’t.


19 posted on 08/24/2021 6:58:27 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Mr.Unique

Do you take anything for your COPD?


20 posted on 08/24/2021 7:00:20 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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