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Benefits of time-restricted eating depend on age and sex (High fat/ sugar diet becomes very healthy)
Medical XPress / Salk Institute / Cell Reports ^ | Aug 17, 2021 | Amandine Chaix et al

Posted on 08/17/2021 12:18:13 PM PDT by ConservativeMind

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles. A new study by Salk scientists further shows that TRE confers multiple health benefits besides weight loss. The study also shows that these benefits may depend on sex and age.

Breaking the conventional young-male-mice mold, the researchers fed a high-fat, high-sugar diet to male and female mice of two age groups (equivalent to 20- and 42-year-old humans), restricting eating to nine hours per day.

Analyzing the tissues of mice on TRE to ascertain their chemical makeup and processes, the researchers found that regardless of age, sex or weight loss profile, TRE strongly protected against fatty liver disease, a condition that affects up to 100 million Americans and for which no medicine has been approved.

"This was our first time studying female mice, and we weren't sure what to expect," says first author Amandine Chaix. "We were surprised to find that, although the females on TRE were not protected from weight gain, they still showed metabolic benefits, including less-fatty livers and better-controlled blood sugar."

The researchers also found that TRE may protect both males and females from sepsis-induced death—a particular danger in ICUs, especially during the pandemic. After administering a toxin that induced a sepsis-like condition in the mice, the researchers monitored survival rates for 13 days and found that TRE protected both male and female mice from dying of sepsis.

TRE didn't just protect against fatty liver disease, diabetes, and death from sepsis; it even enabled male mice to preserve and add muscle mass and improve muscle performance (the effect did not hold for females). This finding is particularly significant for the elderly, for whom improved muscle performance can help guard against falls.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
Apparently, eating a bunch of Twinkies with a limited amount of protein during only a nine hour food ingestion period greatly helps you prevent sepsis, fatty liver, blood sugar issues, while helping male mice grow muscle mass!
1 posted on 08/17/2021 12:18:13 PM PDT by ConservativeMind
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To: ConservativeMind

Not new ... See Jason Fung


2 posted on 08/17/2021 12:21:28 PM PDT by bankwalker (groupthink kills ...)
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To: ConservativeMind

The study refers to (equivalent to 20- and 42-year-old humans).

imho much of the dietary restrictions older people need to go on are not as necessary for young people.


3 posted on 08/17/2021 12:23:35 PM PDT by ckilmer
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To: ConservativeMind

And here I’ve been eating for only a few seconds to 30 minutes at a time my whole life.


4 posted on 08/17/2021 12:27:52 PM PDT by bluejean (Living one day at a time in the national psych ward.)
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To: ckilmer
imho much of the dietary restrictions older people need to go on are not as necessary for young people.

Even that much is only an inference from a mice study.

However, this sort of study would not be hard to replicate in humans.

Limiting eating to 9 hours a day is not a very difficult regime.

Eliminate breakfast and being able to eat from 10 am to 7 pm should not be too difficult for most people.

5 posted on 08/17/2021 12:28:23 PM PDT by marktwain (President Trump and his supporters are the Resistance. His opponents are the Reactionaries. )
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To: ConservativeMind

It’s much easier (and healthier) to exercise in a fasted state as well. I eat in a 3-4 hour window everyday and have never felt better. Hardly ever hungry anymore either.


6 posted on 08/17/2021 12:45:29 PM PDT by erlayman
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To: ConservativeMind

I restrict my eating to my waking hours.


7 posted on 08/17/2021 12:45:50 PM PDT by SoCal Pubbie
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To: bankwalker

Yes, intermittent fasting.


8 posted on 08/17/2021 12:46:55 PM PDT by Bigg Red (Trump will be sworn in under a shower of confetti made from the tattered remains of the Rat Party.)
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To: bankwalker

I liked Fung’s book.
I think he’s spot on, but it’s a lifestyle that’s not easy to live if you’ve spent 70 yrs some other way.


9 posted on 08/17/2021 12:51:15 PM PDT by nascarnation
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To: marktwain

I do intermittent fasting. I eat a small snack by 7:00pm and nothing else until 11:00am the next day. That’s a 16 hour fast. I eat between 11:00am and 7:00pm.

The only time I eat before 11:00am is if the arthritis in my foot is really bad and I need to take an Ibuprofen.


10 posted on 08/17/2021 12:51:41 PM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
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To: ConservativeMind

The article is very weak in explaining TRE, providing only one detail and then only once - restricting eating to a nine hour period (other experts say 6-10).

In practical terms it means that if the first meal commenced at 8 in the morning, the last meal would end at five in the evening. It has a type of modified fasting effect on metabolism.


11 posted on 08/17/2021 1:00:17 PM PDT by Wuli (Biden )
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To: Tennessee Conservative

For your arthritis, if osteo, please look into 3 - 6 mg of boron a day.

You might find lasting relief.


12 posted on 08/17/2021 1:11:59 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: marktwain

I think that there’s something to this. Years ago when I was younger and thinner, I basically ate no breakfast. I had ate an early lunch around 11 and then dinner around 6, i.e., a 7-hour window. And that was it.

As family and work circumstances changed, my eating window has stretched to more like 11-12 hours.


13 posted on 08/17/2021 1:14:45 PM PDT by irishjuggler
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To: ConservativeMind

Thanks! One foot is osteo in the big joint behind my big toe. The other foot is from an injury. I have a cyst type arthritis in the cuboid joint and osteo in the same big joint behind that big toe. I’ll look up the Boron.


14 posted on 08/17/2021 1:31:51 PM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
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To: Tennessee Conservative
Nothing Boring About Boron:

https://freerepublic.com/focus/f-chat/3761669/posts

Amazing inflammation and pain reduction in even the most severe osteo cases. You'll need to page through to the referenced study information.

Basically, everyone I know who started using it no longer has osteo issues. It doesn't rebuild cartilage or block pain, but it reduces overactive inflammation signals with bone while superbly lubricating joint locations.

It gets it done in severe cases within two months at 12 mg/day. The study used fructoborate, but a tri-boron type pill should do well.

15 posted on 08/17/2021 1:44:25 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: erlayman

Agree 1100 %. This is my experience as well.


16 posted on 08/17/2021 1:50:32 PM PDT by GOP Poet (Super cool you can change your tag line EVERYTIME you post!! :D. (Small things make me happy))
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To: erlayman

I meant to write 100% :D. lol.


17 posted on 08/17/2021 1:51:07 PM PDT by GOP Poet (Super cool you can change your tag line EVERYTIME you post!! :D. (Small things make me happy))
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To: ConservativeMind

Sounds like exactly what I need. Checking it out for sure.


18 posted on 08/17/2021 3:11:00 PM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
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