Posted on 07/30/2021 6:59:46 AM PDT by ConservativeMind
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“ARBs do not differ in effectiveness and may have fewer side effects than ACE inhibitors among those just beginning treatment,” said Chen. “We unfortunately cannot extend these conclusions to people who are already taking ACE inhibitors or those who are taking multiple medications. We would reiterate that if you experience any side effects from your medicine, you should discuss with your doctor whether your antihypertensive regimen may need to be adjusted.”
Guys and Girls,
I think I rang the bell here.
High of 190/110 - went to emergency room.
Low of 80/60 - passed out and hit head - went to emergency room.
Not proud of it. I used all of the methods discussed in this thread and now have it in control with minimal meds.
Except excersize.
I am in my lower 50’s years old.
My wife and I both had the ACE cough. She got changed to Metoprolol, I got changed to Losartan.
My blood pressure is fine.
I have no issues requiring any prescription.
The article, and my comments, are fully valid for all who have issues with their other medicines, and for those yet to be placed on such medicines.
For those with white coat hypertension. After the first reading ask the person taking the readings if you can stand up and try it again. You will be amazed at the difference.
Back in high school I had high blood pressure, 135/90-95 range. I went on a serious low carb diet and slimmed down to 150 lbs 5 10”. Kept it off about 20 years and for 3 years didn’t salt anything. My blood pressure stayed high unless I took medication. It’s genetic as my Dad is trim and diet conscious and still has high blood pressure. I have two brothers who deal with it and another brother and sister who have never had an issue.
Currently I’m on lisinopril and a half a fluid pill daily and it’s been stable at 120/76 range regardless of diet for nearly fifteen years. I take the lisinopril before bedtime and fluid pill each morning.
BP tests are usually higher inside the doctor’s office than outside. Weird.
Ok. Made the assumption based on the subject of the article. I take it for granted that all medications have tradeoffs in side effects.
I have made a lifelong practice to avoid meds, even Tylenol as much as possible. When my blood pressure trended up as I got older I was afraid I was going to be stuck on meds that made me feel like crap for life. I was overjoyed to realize that these dietary changes removed any need to depend on medication and I feel better than I did a decade ago.
Oh, and if you like the added risk of sudden pancreatitis or bleeding intestines ACE-I gives you, you can keep your ACE-I.
Not that anyone should give those a thought, right?
It took me until my early 40s to get up to that range. Genetics can play a role, no doubt. I had a grandmother who had potassium control problems that killed two of her brothers with heart attacks before they figured it out.
Lisinopril was one of the better meds my doctor tried on me before I fixed the problem myself.
Have you ever tried breathing exercises? Before the intermittent fasting fixed the problem, I found that slowing my breathing rate down was great for temporary BP reductions. Some people claim teaching your body to do it all the time can work on a permanent basis.
I’m taking and ACE Inhibitor Ramipril but not because of blood pressure issues but rather for its anti inflammatory effects.
I started taking Ramipril a couple months ago—along with a stack of of other ingredients.
The goal is to rid my carotids of plaque build up. Should take another 6-12 months.
When that’s done—I’ll go off ramapril.
My blood pressure is about the same at home as at the doctor’s office. I attribute that to the fact that his nurses don’t wear white coats.
I could not immediately find anything talking to its anti-inflammatory benefits, but I did see that it has some cardio-protective benefits beyond just it normal function.
I also saw that it is closest to the ARB Telmisartan, for such uses.
Ramapril is in the class of ACE inhibitors. I googled “does ramapril have anti inflammation properties”?
Here is 2014 NIH study that concludes
This study determines that a brief episode of ACE inhibitor therapy through 5 mg/day ramipril exerts comprehensive anti-inflammatory effects on vessel wall inflammation in AAA disease. The effect is followed by a general reduction of cell activation.Dec 4, 2014
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256371/#:~:text=This%20study%20determines%20that%20a,general%20reduction%20of%20cell%20activation.
Abdominal aortic aneurysm (AAA) occurs when atherosclerosis or plaque buildup causes the walls of the abdominal aorta to become weak and bulge outward like a balloon. An AAA develops slowly over time and has few noticeable symptoms.
https://www.radiologyinfo.org/en/info/abdoaneurysm#:~:text=Abdominal%20aortic%20aneurysm%20(AAA)%20occurs,and%20has%20few%20noticeable%20symptoms.
Ibesartin is an ARB. I googled “does ibesartin have anti inflammatory properties”?
Irbesartan, an angiotensin II receptor blocker (ARB), acts as a selective PPAR-γ (peroxisome proliferator-activated receptor-γ) modulator, and thus may have anti-inflammatory and antioxidative effects, as well as beneficial effects on glucose and lipid metabolism.Feb 21, 2013
https://www.nature.com/articles/hr20133#:~:text=Irbesartan%2C%20an%20angiotensin%20II%20receptor,on%20glucose%20and%20lipid%20metabolism.
Then I googled. “ACE inhibitor inflammation vs ARB inflammation”
This randomized study tested the hypothesis that ACE inhibitors and ARBs differ in their effects on oxidative stress, inflammation, and fibrinolysis in MHD patients. The major findings are that although short-term treatment with an ACE inhibitor or ARB decreased IL-6 and IL-8, ramipril also exerted a proinflammatory effect during hemodialysis, as measured by an increase in IL-1β and a decrease in the anti-inflammatory cytokine IL-10. Both ramipril and valsartan decreased the marker of thrombosis, D-dimers, but ramipril also prevented a rise in vWf, a marker of endothelial damage, during hemodialysis. These effects are not attributable to an antihypertensive effect of ramipril or valsartan, because neither drug affected BP in the MHD studied participants.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269170/
While the whole was mixed above — the key take away was “ but ramipril also prevented a rise in vWf, a marker of endothelial damage”
WTF is up with you?
I posted a paragraph from the article you posted and nothing more.
Your medical degree is in what speciality exactly?
Now you are accusing me of something?
What exactly are you alleging about me?
I do not argue with morons.
I’ve tried the intermittent fasting and can go a good while but about half the time I get a sick headache. I avoid caffeine so it’s not a caffeine headache. My Mom does the same thing with headaches.
I can do the breathing thing and when in a quiet place get it down to a very slow level. Getting time and quiet is the tricky part for me lol!
Ping
She takes medication for it, Valsartan but I gave her one of my 0.5mg Xanax and in about twenty minutes her bp was 130/64.
I have a pacemaker and take Losartan and Xanax when I need it.
I don't have any bp problems now a days.
Just out of curiosity what are your bp readings?
I’d have to average them out but at home roughly 120/65. In a doctor’s office roughly 150/95.
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