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Is a Coronavirus Vaccine a Ticking Time Bomb?
Science with Dr. Doug ^ | Dr. Doug

Posted on 07/30/2021 1:16:11 AM PDT by tired&retired

“Explanation how ADE works and the future perils it may bring.

For a vaccine to work, our immune system needs to be stimulated to produce a neutralizing antibody, as opposed to a non-neutralizing antibody. A neutralizing antibody is one that can recognize and bind to some region (‘epitope’) of the virus, and that subsequently results in the virus either not entering or replicating in your cells.

A non-neutralizing antibody is one that can bind to the virus, but for some reason, the antibody fails to neutralize the infectivity of the virus. This can occur, for example, if the antibody doesn’t bind tightly enough to the virus, or the percentage of the surface area of the virus covered by the antibody is too low, or the concentration of the antibody is not high enough. Basically, there is some type of generic binding of the antibody to the virus, but it fails to neutralize the virus.

In some viruses, if a person harbors a non-neutralizing antibody to the virus, a subsequent infection by the virus can cause that person to elicit a more severe reaction to the virus due to the presence of the non-neutralizing antibody. This is not true for all viruses, only particular ones. This is called Antibody Dependent Enhancement (ADE), and is a common problem with Dengue Virus, Ebola Virus, HIV, RSV, and the family of coronaviruses. In fact, this problem of ADE is a major reason why many previous vaccine trials for other coronaviruses failed."

(Excerpt) Read more at sciencewithdrdoug.com ...


TOPICS: Health/Medicine
KEYWORDS: vaccine
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To: tired&retired

The warnings are there. This is a March 2020 Journal article:

Medical Countermeasures Analysis of 2019-nCoV and Vaccine Risks for Antibody-Dependent Enhancement (ADE)

https://www.preprints.org/manuscript/202003.0138/v1

“Findings: Non-neutralizing antibodies to variable S domains may enable an alternative infection pathway via Fc receptor-mediated uptake.

This may be a gating event for the immune response dysregulation observed in more severe COVID-19 disease. Prior studies involving vaccine candidates for FCoV5,6 SARS-CoV-17-10 and Middle East Respiratory Syndrome coronavirus (MERS-CoV) 11 demonstrate vaccination-induced antibody-dependent enhancement of disease (ADE), including infection of phagocytic antigen presenting cells (APC).”

“Interpretation: Safety testing of COVID-19 S protein-based B cell vaccines in animal models is strongly encouraged prior to clinical trials to reduce risk of ADE upon virus exposure.”


21 posted on 07/30/2021 2:22:46 AM PDT by tired&retired (Blessings )
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To: tired&retired

Bookmarked


22 posted on 07/30/2021 2:24:39 AM PDT by Fester Chugabrew (No audits. No peace.)
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To: tired&retired

Vaccine, vaccination, vaccinated. etc...Why don’t we ever hear about immunization?


23 posted on 07/30/2021 2:27:21 AM PDT by equaviator (There's nothing like the universe to bring you down to earth.)
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To: Fester Chugabrew

As a homebrewer, I like your screen name.


24 posted on 07/30/2021 2:52:26 AM PDT by tired&retired (Blessings )
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To: tired&retired

We need the actionable intel without them knowing of its existence and we must follow through on all of it.


25 posted on 07/30/2021 3:03:32 AM PDT by equaviator (There's nothing like the universe to bring you down to earth.)
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To: tired&retired

It better go off soon before they forcibly inject us all!


26 posted on 07/30/2021 3:38:52 AM PDT by parmamenian (and so it goes!)
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To: tired&retired
Which is worse ?
Covid ..
or the analgesic jab ?

27 posted on 07/30/2021 3:43:40 AM PDT by Tilted Irish Kilt
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To: pepsionice

How would we be able to tell? Half this country is F-ing nuts as it is.


28 posted on 07/30/2021 3:50:15 AM PDT by VTenigma (The Democrat party is the party of the mathematically challenged )
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To: sneakers

bkmk


29 posted on 07/30/2021 4:04:41 AM PDT by sneakers (It's not the democraTIC party! It's the demoCRAT party! )
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To: Candor7

Thank you for the information!


30 posted on 07/30/2021 4:04:58 AM PDT by Flavious_Maximus (Fauci is a murderer)
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To: tired&retired
Science investigates why it does or does not work in order to find better solutions.

This is correct--unless big corporate profits or big government grants are on the line.

Then scientists turn into back alley whores.
31 posted on 07/30/2021 4:06:23 AM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: tired&retired

The lab animals are waiting for the human trials to be complete before they risk taking any of those vaccines!


32 posted on 07/30/2021 4:07:15 AM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: tired&retired
Better not tell the UK. Check out the dig at US refuseniks. And how Brits don't need a mandate cuz they're so obedient...

JAB SECURITY Brits should get double-jabbed before returning to the office but vaccination WON’T be compulsory, says Grant Shapps

33 posted on 07/30/2021 4:09:06 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: tired&retired

It is interesting. I know Dengue Fever can be more fatal the second time around. But this article was written in Aug 2020, a year ago. I wonder if further information has come out relating to ADE and covid.


34 posted on 07/30/2021 4:27:52 AM PDT by Old_Grouch
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To: tired&retired

You KNOW the one-world government bastards have more things lined up if these latest schemes don’t accomplish their goals. So you are always trying to hit a moving target when trying to overcome their actions.


35 posted on 07/30/2021 4:34:25 AM PDT by Old Yeller (Republican politicans love being in office, Democrat politicians love being in power.)
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To: tired&retired

36 posted on 07/30/2021 4:35:24 AM PDT by Diogenesis (Tuitio Fidei et Obsequium Pauperum)
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To: tired&retired
This is key!
Right now, the fatality rate of the virus is estimated to be approximately 0.26%, and this number seems to be dropping as the virus is naturally attenuating itself through the population. It would be a great shame to vaccinate the entire population against a virus with this low of a fatality rate, especially considering the considerable risk presented by ADE. I believe this risk of developing ADE in a vaccinated individual will be much greater than 0.26%, and, therefore, the vaccine stands to make the problem worse, not better. It would be the biggest blunder of the century to see the fatality rate of this virus increase in the years to come because of our sloppy, haphazard, rushed efforts to develop a vaccine with such a low threshold of safety testing and the prospect of ADE lurking in the shadows. I would hope (and this is a big hope), that this vaccine WILL NOT BE MANDATORY.

37 posted on 07/30/2021 4:56:50 AM PDT by NonValueAdded (Claiming Racism, the antidote to personal responsibility)
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To: tired&retired

It appears that there is NO science in any venue of COVID-19 beyond its inception in the Wuhan Lab, and its Gain of Function research.


38 posted on 07/30/2021 5:00:19 AM PDT by Maelstrom (To prevent misinterpretation or abuse of the Constitution:The Bill of Rights limits government power)
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To: tired&retired

“The West’s Obituary”

https://market-ticker.org/akcs-www?post=241577


39 posted on 07/30/2021 5:10:20 AM PDT by DuncanWaring (The Lord uses the good ones; the bad ones use the Lord.)
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To: tired&retired

“but for some reason, the antibody fails to neutralize the infectivity of the virus “

Because the “vaccine” is crap.


40 posted on 07/30/2021 5:13:18 AM PDT by Rennes Templar (Come back, President Trump.)
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