Posted on 07/28/2021 8:03:10 AM PDT by SeekAndFind
Total antibody levels start to wane six weeks after complete immunisation with Pfizer and AstraZeneca vaccines, and can reduce by more than 50 per cent over 10 weeks, according to a study published in The Lancet journal.
The researchers from University College London (UCL) in the UK noted that if the antibody levels carry on dropping at this rate, there are concerns that the protective effects of the vaccines may also begin to wear off, particularly against new variants.
However, they said, how soon that might happen cannot be predicted yet.
The UCL Virus Watch study also found that antibody levels are substantially higher following two doses of the Pfizer vaccine than after two shots of the AstraZeneca preventive, known as Covishield in India.
Antibody levels were also much higher in vaccinated people than those with prior SARS-CoV-2 infection, they said.
"The levels of antibody following both doses of either the AstraZeneca or Pfizer vaccine were initially very high, which is likely to be an important part of why they are so protective against severe COVID-19," said Madhumita Shrotri from UCL Institute of Health Informatics.
"However, we found these levels dropped substantially over two to three months," Shrotri said in a statement.
The findings based on data from over 600 people aged 18 and above were consistent across all groups of people regardless of age, chronic illnesses or sex, according to the researchers.
The authors highlight that although the clinical implications of waning antibody levels are not yet clear, some decline was expected and current research shows that vaccines remain effective against severe disease.
For Pfizer, antibody levels reduced from a median of 7506 Units per millilitre (U/mL) at 2141 days, to 3320 U/mL at 70 or more days.
For the AstraZeneca vaccine, antibody levels reduced from a median of 1201 U/mL at 020 days to 190 U/mL at 70 or more days, over a five-fold reduction.
"When we are thinking about who should be prioritised for booster doses our data suggests that those vaccinated earliest, particularly with the AstraZeneca vaccine, are likely to now have the lowest antibody levels," said Professor Rob Aldridge from UCL Institute of Health Informatics.
The findings support recommendations that clinically vulnerable adults, those aged 70 years or over, and all residents of care homes for older adults should be prioritised for booster doses, the researchers said.
In addition, those who were vaccinated with the AstraZeneca vaccine are likely to have much lower antibody levels than those vaccinated with the Pfizer vaccine, they noted.
"This may also need to be considered when deciding who should be prioritised when boosters are rolled out," Aldridge said in the statement.
The team acknowledged certain limitations in the data, including a small sample size for some groups.
The researchers noted that each individual only contributed one sample, so they cannot yet confirm how quickly antibody levels drop for each individual, or whether these would continue to drop or reach a stable level over the next few months.
They also noted that different people will have different levels of immunity depending on the virus neutralising ability of their antibodies as well as their T-cell responses.
"Even when measurable antibody levels are low, there is likely to be continuing immune memory that could offer long-term protection," the authors of the study noted.
They said further research will be important to establish if there is an antibody level threshold needed for protection against severe disease.
Natural immunity, (herd immunity) is the only real way to defeat covid-19 and its variants.
eg SWEDEN
The never-ending injection.
A Special message from Big Pharma
“You are not just a patient, you are more importantly a revenue generating unit. It’s important that you continue to be so. And its important that you get a vaccine at least once per year! We in Big Pharma, are dedicated to more treatments and fewer cures, because its important that we continue to rely on you to do your part and maintain your Revenue Generating Unit status!
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I wish they had examine T Cells & B cells.
How can you claim that when noone who has caught Covid-1 has lived 17 years yet? only 8,000 Sars2003 cases worldwide - that’s not a lot of people with ‘natural immunity’. Does natural immunity against Covid-1 mean natural immunity against Covid-Delta or Lambda? or all coronaviruses?
https://www.cdc.gov/media/presskits/sars/cases.htm
https://en.wikipedia.org/wiki/2002%E2%80%932004_SARS_outbreak
“You are not just a patient, you are more importantly a revenue generating unit
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Right you are. From Peter Daszak -
Until an infectious disease crisis is very real, present, and at an emergency threshold, it is often largely ignored. to sustain the funding base beyond the crisis, he said we need to increase public understanding of the need for MCMs such as a pan-influenza or pan-corona vaccine.
A key driver is the media and the economics follow the hype. We nee to use that hype to our advantage to get to the real issues. Investors will respond if they see profit at the end of process.
How can you claim that when noone who has caught Covid-1 has lived 17 years yet? only 8,000 Sars2003 cases worldwide - that’s not a lot of people with ‘natural immunity’. Does natural immunity against Covid-1 mean natural immunity against Covid-Delta or Lambda? or all coronaviruses?
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SARS was more than 17 years ago. And it is very similar to this virus.
The 80% estimate comes from a study that showed that the impact differed depending upon how similar to CV19 the prior exposure was.
The study included review of blood that was taken before the CV19 outbreak. It showed that prior coronavirus(not just SARS) also had some demonstrated immunity. The T cell and neutralizing antibodies were found to be more important than the binding antibodies.
The vaccines are heavy on the binding and not so good on the other categories. That might have something to do with why the vaccine is losing effectiveness faster than anticipated.
So far, it’s looking like the traditional inactivated virus vaccine method would have been a better way to go.
...So far, it’s looking like the traditional inactivated virus vaccine method would have been a better way to go....
yeah but there were billions of dollars to be made, thus prohibit cheap medicines like hydroxychloroquine and ivermectin..
if i was a big shot at these “vaccine” companies or others pushing this vax like illegal drug dealers(first one is free!) i would be very afraid imo we are close to tshf
...So far, it’s looking like the traditional inactivated virus vaccine method would have been a better way to go....
yeah but there were billions of dollars to be made, thus prohibit cheap medicines like hydroxychloroquine and ivermectin..
if i was a big shot at these “vaccine” companies or others pushing this vax like illegal drug dealers(first one is free!) i would be very afraid imo we are close to tshf
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And also, don’t forget, they had never had enough success/safety in the animal tests to progress to human trials. Just think how many years of research and development they bypassed to get such a huge human trial-they data they must be collecting!
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