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High doses of vitamin D rapidly reduce arterial stiffness in overweight/obese, vitamin-deficient African-Americans
Science Daily / Medical College of Georgia at Augusta University / PLOS ONE ^ | Jan 2, 2018 | Anas Raed, Jigar Bhagatwala, Haidong Zhu, Norman K. Pollock, Samip J. Parikh, et al

Posted on 07/26/2021 2:15:10 PM PDT by ConservativeMind

In just four months, high-doses of vitamin D reduce arterial stiffness in young, overweight/obese, vitamin-deficient, but otherwise still healthy African-Americans, researchers say.

Rigid artery walls are an independent predictor of cardiovascular- related disease and death and vitamin D deficiency appears to be a contributor.

In what appears to be the first randomized trial of its kind, they found that arterial stiffness was improved by vitamin D supplementation in a dose-response manner in this population, they write in the journal PLOS ONE.

Participants taking 4,000 international units -- more than six times the daily 600 IUs the Institute of Medicine currently recommends for most adults and children -- received the most benefit.

The dose, now considered the highest, safe upper dose of the vitamin by the Institute of Medicine, reduced arterial stiffness the most and the fastest: 10.4 percent in four months. "It significantly and rapidly reduced stiffness," Raed says.

Two thousand IUs decreased stiffness by 2 percent in that timeframe. At 600 IUs, arterial stiffness actually increased slightly -- .1 percent -- and the placebo group experienced a 2.3 percent increase in arterial stiffness over the timeframe.

The Institute of Medicine currently recommends a daily intake of 800 IUs of vitamin D for those age 70 and older. For adolescents and adults, they recommend 4,000 IUs as the upper daily limit; 2,000 was a previous upper limit.

More than 80 percent of Americans, the majority of whom spend their days indoors, have vitamin D insufficiency or deficiency.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine
KEYWORDS: arterialstiffness; vitamind
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Strangely, this does not appear related to calcium “hard” plaques. No calcium scan (CT or Ultrasound) was performed.

It was in a group of people unlikely to have calcium, due to age.

So it appears Vitamin D helped either with removing soft plaques or with the innate flexibility of the vessels, regardless of plaque formation.

It looks like we definitely need to supplement with more than 600 IUs, which was so little that it increased stiffness.

1 posted on 07/26/2021 2:15:10 PM PDT by ConservativeMind
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To: ConservativeMind

It is as if encouraging Africans to move to low light northern latitudes is HARMFUL to them....


2 posted on 07/26/2021 2:16:39 PM PDT by GraceG ("If I post an AWESOME MEME, STEAL IT! JUST RE-POST IT IN TWO PLACES PLEASE")
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To: ConservativeMind

my primary doctor really promotes Vitamin D. He says especially in the North, its absolutely necessary to supplement


3 posted on 07/26/2021 2:19:59 PM PDT by PGR88
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To: ConservativeMind
The Antibiotic Vitamin (Antiviral Too)
4 posted on 07/26/2021 2:21:55 PM PDT by blam
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To: PGR88

My Doctor as well. I’ve been taking supplements for a couple of years.


5 posted on 07/26/2021 2:24:02 PM PDT by Huskrrrr (Pronouns? I need no stinkin pronouns!)
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To: ConservativeMind

I suspect vitamin D deficiency is a much bigger problem than previously realized, and not just for black people. I have been taking 2-3000 IU for three years and have not been ill once.


6 posted on 07/26/2021 2:27:30 PM PDT by buwaya
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To: ConservativeMind

D3, calciferol is the one to take.


7 posted on 07/26/2021 2:28:55 PM PDT by Fungi
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To: Fungi

For the past 20 years, I’ve had psoriasis with psoriatic plaques on both legs. Everyone told me to take 5-6000 IU daily. It did nothing. 4 months ago I switched to 50,000 IU and my plaques have shrunk by 95% and are nearly gone.


8 posted on 07/26/2021 2:35:55 PM PDT by BuffaloJack (... to the Republic for which it stands ...)
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To: ConservativeMind

bkmk


9 posted on 07/26/2021 2:36:14 PM PDT by sauropod (Amateurs built the ark; Professionals built the Titanic. Anon)
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To: BuffaloJack

What kind of testing did you have done?


10 posted on 07/26/2021 2:38:43 PM PDT by ConjunctionJunction
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To: buwaya

Honestly, that is not that much.


11 posted on 07/26/2021 2:39:51 PM PDT by battletank
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To: ConservativeMind

Vitamin D deficiency is also a big risk factor for severe covid.

Another sign of Fauci’s malfeasance is his failure to inform and educate the public about Vitamin D3 supplements


12 posted on 07/26/2021 2:44:42 PM PDT by silverleaf (In a time of universal deceit, telling the truth is a revolutionary act)
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To: BuffaloJack

That seems like an extremely heavy dose. Be careful. Have heard of problems taking too much.


13 posted on 07/26/2021 2:45:19 PM PDT by zek157
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Comment #14 Removed by Moderator

To: ConservativeMind

Ironically, vitamin D production from sunlight is actually related to skin color. Are we sure it’s not culture?


15 posted on 07/26/2021 2:56:00 PM PDT by cdcdawg (It's all so tiresome.)
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To: ConservativeMind

K2/D3 combo


16 posted on 07/26/2021 3:04:21 PM PDT by struggle
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To: ConservativeMind

Bttt


17 posted on 07/26/2021 3:14:48 PM PDT by Guenevere (When the foundations are being destroyed what can the righteous do)
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To: ConservativeMind
" more than six times the daily 600 IUs the Institute of Medicine currently recommends for most adults and children -- received the most benefit."

The FDA always recommends concentration camp ration amounts of vital nutrients. Good for business.

.

"Sensible sun exposure, especially between the hours of 10:00 am and 3:00 pm produces vitamin D in the skin that may last twice as long in the blood compared with ingested vitamin D. [4] If sun exposure produces slight pinkness, the amount of vitamin D produced in response to exposure of the full body is equivalent to ingesting 10,000-25,000 IU."

https://www.medscape.com/answers/128762-54304/what-is-the-recommended-sun-exposure-for-production-of-vitamin-d

18 posted on 07/26/2021 3:15:54 PM PDT by Karl Spooner
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To: Levy78

“Didn’t know one could take that much”

Fauci has said he takes 6-8000 per day. If you want to believe him. He lies so much these days.


19 posted on 07/26/2021 3:22:56 PM PDT by Polynikes ( Hakkaa paalle)
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To: ConservativeMind

Vit D3 is being recognized as more important every day:

Vit D3 helps with chronic urticaria (hives) - dose is 4,000 IU daily. I have this issue - take 5K daily. This usually keeps hives away, but if they do occur, another 10K generally resolves the issue without an antihistamine.

++++++++++++++++++++++++++++++++++++++++++++++++++

Dr. Zelenko recommends 5,000 IU daily for his COVID prohylaxis protocol.

https://vladimirzelenkomd.com/zelenko-prophylaxis-protocol/

++++++++++++++++++++++++++++++++++++++++++++++++++

The Vit D “Hammer” -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463890/

” In those patients who do have influenza, we have treated them with the vitamin D hammer, as coined by my colleague. This is a 1-time 50 000 IU dose of vitamin D3 or 10 000 IU 3 times daily for 2 to 3 days. The results are dramatic, with complete resolution of symptoms in 48 to 72 hours. One-time doses of vitamin D at this level have been used safely and have never been shown to be toxic.8 We urgently need a study of this intervention. The cost of vitamin D is about a penny for 1000 IU, so this treatment costs less than a dollar.”


20 posted on 07/26/2021 3:23:38 PM PDT by Qiviut (Faith is the antidote to fear. Mindset: be a victor, not a victim.)
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