Skip to comments.Covid Vaccines: The Good, The Bad, The Ugly
Posted on 07/24/2021 3:44:28 PM PDT by ransomnote
ransomnote: I trimmed the image to include only the portion in English - full image at link.
Israel: Pfizer vaccine effectiveness by outcome and time of vaccination (MOH/Segal)
The latest data from Israel and the UK on covid vaccine effectiveness.
The latest data from Israel, which has used primarily the Pfizer mRNA vaccine, indicates that vaccine effectiveness against Delta coronavirus infection and symptomatic (“mild”) disease has dropped from about 95% to about 40%, whereas effectiveness against hospitalization and severe disease (i.e. low blood oxygen levels) remains at 80% to 90% (see chart above).
Importantly, in people who got vaccinated already in January 2021 (primarily the elderly), protection against infection and mild disease may already have dropped to near 0% (see chart above). Moreover, since the Delta covid outbreak is still accelerating in Israel, the effectiveness against hospitalization and severe disease may further decrease (due to lags in hospitalizations).
In the UK, which has primarily used the AstraZeneca DNA adenovector vaccine, the latest estimate by researchers at the University College London indicates an effectiveness against infection of close to zero percent and an effectiveness against severe disease of about 60%. In very senior citizens, the effectiveness against severe disease may be even lower (due to a weaker immune response).
(A substantially higher estimate by Public Health England, recently published in the New England Journal of Medicine, was based on outdated data from early June. Interestingly, the British government hasn’t updated its data on AstraZeneca vaccine effectiveness since June 13.)
The Israeli data shown above indicates that effectiveness against infection and mild symptoms decreases rapidly over time and reaches near-zero levels after about half a year. Most likely, this is because covid vaccines do not achieve mucosal immunity (in contrast to natural infection) and serum antibody levels (i.e. antibodies in the blood) decrease within months.
Thus, the false promise of very high protection against “symptomatic infection”, found during official vaccine trials, was simply based on very high short-term serum antibody levels mimicking mucosal immunity. The pharmaceutical companies probably even knew that this was just a (very lucrative) “flash in the pan” and not a lasting protective effect.
In contrast, protection against severe disease is achieved by lower serum antibody levels in combination with immunological memory (B cells) and cellular immunity (T cells). However, the Delta variant has already achieved partial immune evasion (as did Beta and Gamma, but not Alpha), and future coronavirus variants will likely achieve almost complete immune evasion.
Thus, vaccine protection even against severe disease will likely further decrease due to new variants, or, in the very worst case, will turn into antibody-dependent disease enhancement (ADE), if high levels of non-neutralizing antibodies aggravate the infection. Indeed, this is what happened in the case of vaccines against SARS-1 and dengue fever.
MUCH MORE AT LINK
ransomnote: I really don't know what the stats mean now that they finally admitted that the PCR does not distinguish between the flu and Covid, and the 'vaccine' trials used the PCR to determine whether or not the vaccine 'worked'.
The PCR doesn't distinguish between the flu and Covid
Did the research. I like the Russian vaccine. It’s adenovirus but different because it uses two vectors, no chimpanzee thing like Astra, went through delicate yet rigorous filtration process, and also comes in a one dose Sputnik “light” option.
of course can’t get that here.
There’s talk of Johnson and Johnson and Astra improving on theirs with modifications yet no talk of consulting with their Russian betters.
I guess if you’re Bill Gates, these shots are working 😩😡
Hey, it’s an experiment. These things happen.
No genetically modified injections for me.
If they had a traditional inactivated virus JAB I might have considered taking it.
I’ll stick with my God - given immune system and try to get that as primed as possible. Meanwhile, prepare for the worst and pray for the best.
Blessings to you for all the interesting info you bring to the forum. 👍
so the people who got the earliest jabs (like the elderly) have been losing their immunity already???? yikes.
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I guess we will find out this late fall.
A friend of mine who has a transplanted kidney and on lots of immune suppressive meds had the shots in January. He just got covid, I guess, severe body pain, coarse tremors, knocked down pretty hard, respiratory difficulties, avoided the vent so far.
Could be an indication of what is coming.
I think you’re on the right track. My wife and I both caught Covid and had it, no hospital, but it wasn’t fun, really before it became a ‘thing’, courtesy of picking up my daughter on a Christmas Eve flight to come visit us, with a bunch of Chinese on board with her. (Seriously)
First time my wife was sick about 10 days, got some bronchial meds from local hospital (remember, they didn’t really know what it was yet!) I was sick for about 3 days, but I was able to keep myself going enough to keep track of her, but after about three days, I could see she was improving, too. (January 2020)
2nd exposure was at her work, December 2020. She sure as heck had a positive test, and she had an immediate immune response as well...but the symptoms lasted about 24-36 hours, no 10 days. I, of course, was sharing a bed with her, and, had an immune response, too...but after a good night’s sleep, I was done with that.
3rd time, sometime in June or JUly, they’ve had a pretty good surge of Delta around here. We got exposed, we suspect just while going out to eat, and had light symptoms that matched Delta, and what I would call ‘feeling a bit off’ for about a day, then slept well that night, and, well, there goes Delta.
I’m no immunologist, but that says to me that while, yes, there are variants, people with good immune systems that have had it, their systems will recognize the variants and stomp on them fairly quickly, but there will be a small time lag while your body realizes this is known...but not quite.
No vaccine for either of us, but, we just shrug and continue on. Unless some super-mutation comes along that my body no longer recognizes *at all*, I’m good to go. Daughters in Oregon are still ok. Son and daughter at home were exposed to all this at home, and barely had any reaction at all.
I do work from home a lot, but, most of the crew that were there in December of 2020 and came to the office at all got exposed anyway. The only Delta people at my work were the ‘new since February’ people.
We will see. Prayers for all, that you might weather this storm yourselves, families and all.
Thanks. Very interesting. Dr. McCullough said that if you haven’t had it by now the chances of getting it are about 1%.
As far as I know I haven’t had it. I felt like I had a fever for a few hrs. My temp was 98.6 (it’s normally 97) so I just went to bed to get a good night’s sleep.
Was not about to call someone for what they consider a normal temp without some other significant symptom. Ha.
The other thing I should mention, after noting that you mentioned about ‘priming’ your immune system:
Once we knew it was coming (and were starting to realize we had already had it.) I was careful to not get myself caught short on sleep or ‘strung out’ by too much work and not enough sleep; i.e. I tried to make sure my immune system had a good chance at whatever came along, and was more diligent about it than usual.
I don’t think someone can wave a magic ‘vax’ or ‘jab’ at the problem and make it go away. Actually immunity is the only route we have available for now, I think.
Time will tell.
Nothing special, really, but, it could make a difference.
Simply put, while there have definitely been exceptions, it seems like the biggest killer I’ve observed with Covid is that it simply overwhelms people who are already have a problem or deficiency of some kind. I lost a couple relatives and some other friends or relatives of friends to this myself, so please don’t try to accuse me of saying cruel things. Nature will kill you if you’re already in trouble, and won’t apologize.
Yes, I remember the Med Cram guy saying that sleep was the most important part. So I’ve tried to make sure and get a good night’s sleep.
Well, it’s true “shrug” the frail old people don’t do so well. My Dad was housebound and I took care of him for 5 years. Every time his home health people came to visit, he would wind up catching something like the flu and it would land him in the hospital.
I always stayed with him at the hospital until he could come back home. The stroke had rendered his ability to communicate difficult, and he would get very anxious if I was not there. He passed on Pearl Harbor anniversary in 2008.
I would be beyond upset if I had to let anyone in my family be alone in the hospital today. Unbelievable that people have to die alone.
Novavax is what I am wait on,
Keeping an eye on it. However, it too doesn’t contain the inactivated virus and it’s relevant to the true durability to have that. Some additional info on how novavax gets the “spike” protein, but doesn’t have the actual virus.
If Bill Gates was a mechanic...
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