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Novavax COVID-19 Vaccine Less Likely to Cause Side Effects Compared to the mRNA Vaccines
Very Well Health ^ | 07/16/2021 | Carla Delgado

Posted on 07/16/2021 9:37:42 PM PDT by SeekAndFind

Key Takeaways

Early last month, the pharmaceutical company Novavax shared that its two-dose COVID-19 vaccine was more than 90% effective at preventing COVID-19.

But experts have pointed to an additional interesting tidbit in the research: This new vaccine may cause fewer side effects than those currently available in the U.S.

Based on their data, the Novavax vaccine has a significantly lower rate of side effects compared to the Pfizer-BioNTech and Moderna vaccines. The symptoms commonly reported were similar to those already associated with COVID-19 vaccines like fatigue, headache, and muscle pain.

The company plans to file for U.S. Food and Drug Administration (FDA) approval. As vaccination rates stall nationwide, an additional vaccine like Novavax may seem unnecessary. But the possibility for fewer side effects and the use of reliable, trusted vaccine technology may work to convince those who remain unvaccinated to get their shot.

Fewer Side Effects May Encourage People to Get Vaccinated

Vaccine side effects can be an important factor affecting whether people get the jab.

According to the Kaiser Family Foundation, nearly half of unvaccinated adults worry about missing work if the vaccine's side effects make them feel sick for a day or more.

“Lower rates of vaccine side effects are important, in particular for adults who are concerned about lost wages or unscheduled time away from work,” Tanjala Purnell, PhD, assistant professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health, tells Verywell. “On average, hourly-wage workers often earn less overall income as compared with salaried workers. Therefore, these clinical trial results may be especially appealing to people who have concerns about loss of income due to sick days or potential time away from work due to vaccine side effects and/or complications.”

If a vaccine like Novavax that causes fewer or less severe side effects becomes available, vaccination rates may increase among people in lower-income communities who can't afford to miss a day’s worth of pay. According to recent Census Bureau data, more than half of unvaccinated Americans live in households that make less than $50,000 annually.

“For example, an adult who is employed in an hourly-wage job may have less schedule flexibility and less job security than a person who is employed in a salaried position,” Purnell says. “Because of our current system of employer-based health insurance in the U.S., concerns about job security may also lead to concerns about disruptions in access to healthcare, in the event of job loss.”

What This Means For You

Some employers are offering paid time off for COVID-19 vaccine appointments and subsequent recovery days. If you haven't been vaccinated yet and you're concerned about losing a day's worth of pay, it's best to check with your employer. To look for available vaccine appointments near you, visit Vaccines.gov.

The Difference Between Novavax and mRNA Vaccines

But what's behind this difference in side effects? It may due to the vaccine mechanisms at work.

The Pfizer-BioNTech and Moderna mRNA vaccines and the Novavax protein-based subunit vaccine were developed using different technology.

Subunit Vaccines

Novavax was developed using protein-based, subunit technology.

Subunit vaccines do not include any live components, containing only the specific parts of a viral or bacterial pathogen. These parts—subunits—are what the immune system needs to be exposed to so it can recognize them and develop a protective response.

“We have experience with this well-established technology and these vaccines are relatively very stable,” Inci Yildirim, MD, PhD, vaccinologist and pediatric infectious diseases specialist at Yale Medicine and associate professor of pediatrics and global health at the Yale School of Medicine, tells Verywell. “They are also relatively cheap and easy to produce. There is no live virus or bacterium in these vaccines, so certain groups such as individuals with immunocompromising disease can receive these vaccines.” 

Subunit vaccines are reliable and familiar—they have been around for many years. This technology is behind many of the routine childhood vaccinations for whooping cough, diphtheria, tetanus, and hepatitis B. They are also more stable and easier to store, unlike mRNA vaccines that require ultra-cold conditions for distribution. 

“There is a huge experience behind this technology,” Yildirim says. “Some people may find this appealing, and we may have more people getting vaccinated. The subunits included in the vaccine are necessary to elicit a protective immune response, but they are not live, or they are not whole viruses and cannot cause disease in the vaccine recipient.”

New mRNA Technology

The mRNA COVID-19 vaccines don’t use a weakened or inactivated virus to trigger an immune response either. They both use a new type of vaccine that teaches the cells to make a spike protein so the immune system can build a response against it.

Examining the specific parts of a viral or bacterial pathogen to include in a subunit vaccine is a tedious process. But that process is much easier when making mRNA vaccines.

“Determining the best antigen to include in the vaccine takes time and it will take longer to change this antigen if needed,” Yildirim says. “This will take much less time with mRNA vaccines since once the genomic target is identified, mRNA signature can be quickly and easily edited, and a new version of the vaccine can be manufactured. We have started our clinical trials with NIH/Moderna mRNA vaccine against SARS-CoV-2 within two months after the genome of the virus was sequenced.”

Aside from their technology, mRNA and subunit vaccines also differ in the immune response they evoke in the body.

“Subunit vaccines are expected to trigger only antibody-mediated immune responses,” Yildirim says. “mRNA vaccines against SARS-CoV-2 have been shown to induce B cell and T cell responses.”

This, however, doesn't drastically change efficacy rates.

“The overall efficacy of these three vaccines is similar, ranging between around 90% to 95%,” Yildirim adds. “They all have 100% efficacy for severe COVID-19 disease.”

Novavax Approval Could Still Help

It remains to be seen whether this report of fewer side effects holds up in a real-world setting.

But whether the Novavax vaccine is less likely to cause side effects or not, having a potential fourth COVID-19 vaccine in the U.S. is still beneficial.

With the approval of Novavax, healthcare providers and individuals would have more options to choose from, which may increase national and global demand.

“It is certainly important for us to have access to several vaccines that are effective against COVID-19,” Purnell says. “Globally, we continue to learn about new variants of the COVID-19 virus, and we are still learning more about long-term vaccine effectiveness over time. If we need additional booster shots in the future, it will be important for us to have an appropriate vaccine supply here in the U.S.”

The information in this article is current as of the date listed, which means newer information may be available when you read this. For the most recent updates on COVID-19, visit our coronavirus news page.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid19; novavax; sideeffects; vaccine
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1 posted on 07/16/2021 9:37:42 PM PDT by SeekAndFind
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To: SeekAndFind

I’ve been watching Novavax from the start, and will consider it if it becomes available.

No effing way I’m ever taking an mRNA jab.


2 posted on 07/16/2021 9:47:27 PM PDT by datura (The voice that brought you peace has nothing left to say.)
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To: datura

Why take any shot for something that’s 99.8% survivable?

Do you take a shot for falling down stairs prevention? Would that shot really keep you from falling down stairs?


3 posted on 07/16/2021 9:49:13 PM PDT by Jane Long (America, Bless God....blessed be the Nation.)
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To: Jane Long

Novavax is closer to a traditional vaccine. It’s providing parts (subunit) of the virus for the immune system to respond against. Best way I understand it is the mRNA vac try to turn you body into the production site where novavax actually produced the proteins and put them in their vax. So no mRNA, Andro virus payload ...

“The protein subunit vaccine contains purified “pieces” of a pathogen rather than the whole pathogen to trigger an immune response. It is thought that by restricting the immune system to the whole pathogen, the risk of side effects is minimized.”


4 posted on 07/16/2021 10:01:34 PM PDT by wgmalabama (We will find out if the Vac or virus risk was the correct choice - can we put truth above narrative?)
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To: Jane Long

“Fewer Side Effects May Encourage People to Get Vaccinated”

No.
It won’t.


5 posted on 07/16/2021 10:11:52 PM PDT by Salamander (We Have Forgotten The Faces Of Our Fathers....)
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To: Jane Long

If I become required to have a vax to continue in my business (crossing the border into Canada daily), I will have little choice if I want to keep financially solvent. Lots of equipment involved. Until then, I’ll continue to rely on the prophylaxis regimen I’ve been on the entire time.

Having been an essential worker all thru this, I haven’t been sick. No mRNA ever. A conventional vaccine like Novavax is no big deal after all the shots I’ve had in the Army for overseas deployments.


6 posted on 07/16/2021 10:15:57 PM PDT by datura (The voice that brought you peace has nothing left to say.)
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To: SeekAndFind

There is ZERO compelling health reason to take any of these new FRANKENSTEIN vaccines when there are other alternatives that are just effective or more so without all the risks.


7 posted on 07/16/2021 10:52:47 PM PDT by BiglyCommentary
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To: SeekAndFind; Jane Long; ransomnote; SecAmndmt; Secret Agent Man; Jan_Sobieski; bagster; ...

Ooops, did they just admit serious enough side effects that the vax needed adjusting?


8 posted on 07/16/2021 10:59:28 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith…)
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To: SeekAndFind
Study: Stay-at-Home COVID Orders Were a Luxury Many Couldn't Afford

Who knew that being locked down with stay at home orders was a “luxury”?

It’s amazing the insight into the twisted, evil mind some of their statements can unintentionally reveal to the world.

9 posted on 07/16/2021 11:02:18 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith…)
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To: SeekAndFind

The question is not so much whether the “vaccine” is conventional or not, the question is, does it introduce the spike protein (aka “liquid sandpaper”) into your body? Do labs indicate that it contains graphene oxide?


10 posted on 07/16/2021 11:10:01 PM PDT by The Duke (Search for 'Sydney Ducks' and understand what is needed.)
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To: metmom
Ooops, did they just admit serious enough side effects that the vax needed adjusting?

~~~~~~~~~~~~~~
That would be a 'yes'.

As the dangers of each type of Covid 'vaccine' surface, they start waving a flag yelling "Over Here! New VAX! This one's better! Promise."

I consider Novavax appalling - it's an injection of pure spike proteins.

This is from a prior post re Novavax:

 

Novavax was a failed company, in the stock market, going out of business, and located in Maryland.

Novavax is an injection of pure spike proteins, the ones that are causing devastating harm in all the other vaccines. They are not 'better.'

My notes on Dr. John Campbell's video "TUESDAY UPDATE" in which he reviews Novavax and a small Ivermectin study in Israel.
youtube.com ^ | Jun 15, 2021 | Dr. John Campbell and vanity

Posted on 6/16/2021, 2:03:15 AM by ransomnote

Dr. Campbell notes that he's reading from a press release and the vaccine research has not been peer reviewed yet.

ransomnote: I was wondering why there were so many news articles for Novavax all dated 6/14. Almost like press releases = free advertising from MSM. I saw elsewhere that Novavax development was also supported by the Bill & Melinda Gates foundation, among others.

How Novavax works:

DNA designed to make the spike proteins is put into another virus and that virus is put into moth cells. The DNA instructs the moth cells to mass produce the spike proteins, then the spike proteins are harvested (purified) from the moth cells. 

The spike cells stick together and have the antigenic properties of the Sars 2 Covid virus, without the actual presence of the Covid virus.

ransomnote: Covid spike proteins are causing harm in other vaccines. Inventor Of mRNA Vaccine Technology: Spike Protein Is Dangerous, Its Cytotoxic. The FDA Was Warned About It Months Ago

First case of postmortem study in a patient vaccinated against SARS-CoV-2 [Spike Protein in every organ in his body!] or transcript:

Dr. Mercola Explains Dr. Bridle’s Bombshell Revelations Regarding Spike Proteins from Vaccines

Former Chief Science Officer at PFIZER VP: “THE THING TO BE TERRIFIED OF IS YOUR GOVERNMENT” (bitchute.com) Dr. Yeadon

Compared with the mRNA vaccines and DNA 'vaccines', which tell your own body cells to produce the spike protein, the Novavax is designed to directly inject the spike proteins into your body. 

Novavax was tested against a Covid variant very similar to, but not the same as, the original Covid virus.

Currently being tested on 2248 children 12 - 18 years of age.

Novavax received 1.6 Billion in NIAID (Fauci) federal funds to pay for 100 million future doses.

There's no need to experiment on yourself with these 'vaccines' when so many safe, effective medication protocols are available.

Early Treatment Protocols (Collection of Covid-19 resources, treatment and prophylactic protocols)

The following link describes some of the ways you can get Ivermectin.

Why are we not using ivermectin for Covid? (freerepublic.com)

11 posted on 07/16/2021 11:20:17 PM PDT by ransomnote (IN GOD WE TRUST)
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To: datura
I’ve been watching Novavax from the start, and will consider it if it becomes available.

No effing way I’m ever taking an mRNA jab.

The side effects of the mRNA vaccines aren't so bad. They go away after a couple of days anyway. If people are afraid of missing work, get the vaccination on a Friday. The side effects should be gone by Monday. I got my injections in August and September of last year. Maybe the Norovax is a great vaccine, but I wasn't willing to wait for it. I might be interested in it as a booster if a booster is needed, but I wouldn't go around unvaccinated waiting for it.

12 posted on 07/16/2021 11:48:06 PM PDT by Paleo Conservative ( )
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To: SeekAndFind

It will have zero side effects with me. I know of exactly zero people who had covid but do know my daughter was getting ill being around the vaccinated on her job. It got so bad she told all her clients not to book with her until 30 days after they get the shot.


13 posted on 07/17/2021 1:35:29 AM PDT by roving
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To: Jane Long
This is the first I've heard of a shot to keep me from falling downstairs. Count me in. Where do I get this?

/s

14 posted on 07/17/2021 6:13:03 AM PDT by BipolarBob (You may love gravity but gravity does not love you back.)
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To: datura

I’m only on my 2nd cup of coffee...don’t feel like reading all that.

What makes Novavax different? Was it produced similar to a traditional viral vaccine? Does it contain or was it developed / produced utilizing aborted fetal cells and or tissue?


15 posted on 07/17/2021 6:32:22 AM PDT by servantboy777
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To: wgmalabama

But do they utilize HEK-239 (human embryonic kidney) cells/tissue or similar aborted fetal lines to develop and or produce Novavax vaccine?

I will not support the abortion industry at all.

Read a piece years ago regarding stem cell research and the use of aborted fetuses in the research. The point of the article was that the need for aborted fetal tissue could be replaced with donated ambilocal cord blood/tissue rich in stem cells rather than supporting the abortion industry.


16 posted on 07/17/2021 6:37:21 AM PDT by servantboy777
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To: SeekAndFind

IF, and that’s a big if, this is the vaccine I will take. But only if an antibody test comes back negative.


17 posted on 07/17/2021 7:51:40 AM PDT by NonValueAdded (Claiming Racism, the antidote to personal responsibility)
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To: BipolarBob

Gravity does too love you back, that is why it is so anxious to bring you closer. That you make a thud when experiencing a gravity-induced hug is your mistake. Look at snakes. They don’t thud.


18 posted on 07/17/2021 9:14:41 AM PDT by bobbo666 (Baizuo)
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To: Jane Long
No, but it would reportedly prevent you from killing other people by pushing them down the stairs.

See how that works? Must cover all objections even with fiction and lies.

19 posted on 07/17/2021 9:17:23 AM PDT by glennaro (Dennis Prager: "Until it's safe" means "Never")
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To: glennaro

😂😂😂👍🏻👍🏻


20 posted on 07/17/2021 9:20:53 AM PDT by Jane Long (America, Bless God....blessed be the Nation.)
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