Yes, that is a good link to save. Actually, fantastic!
.
Posted on 06/23/2021 8:31:46 PM PDT by SeekAndFind
The University of Oxford announced Wednesday it is investigating antiparasitic drug ivermectin as a possible treatment for Covid-19, a trial that could finally resolve questions over the controversial medicine which has been widely promoted around the world despite warnings from regulators and a lack of data supporting its use.
KEY FACTS
* Ivermectin will be assessed as part of the U.K. government-backed Principle study, which assesses non-hospital treatments against Covid-19 and is a large-scale randomized control trial widely considered the “gold standard” in evaluating a medicine’s effectiveness.
* While studies have shown ivermectin to inhibit virus replication in a lab, studies in people have been more limited and have not conclusively demonstrated the drug’s effectiveness or safety for the purpose of treating Covid-19.
* The medicine has a good safety profile and is used widely around the world to treat parasitic infections like river blindness.
* Professor Chris Butler, one of the study’s lead investigators, said the group hopes “to generate robust evidence to determine how effective the treatment is against Covid-19, and whether there are benefits or harms associated with its use.”
* Ivermectin is the seventh treatment to be tested in the Principle trial, two of which—the antibiotics azithromycin and doxycycline—were found to be generally ineffective in January and one—an inhaled steroid, budesonide—was found to be effective at reducing recovery time in April.
Dr. Stephen Griffin, an associate professor at the University of Leeds, said the trial should finally provide an answer to questions over whether ivermectin should be used as a drug targeting Covid-19. “Much like hydroxychloroquine before, there has been a considerable amount of off-label use of this drug,” primarily based on studies of the virus in laboratory settings, not people, and using safety data from its widespread use as an antiparasitic, where much lower doses
(Excerpt) Read more at forbes.com ...
Ping for your interest
You’re about 18 months late, Great Britain.
But, better late than never.
They will never allow it, because it will threaten the covid vaccines EUA.
Dear vaxxers,
We have been lying to you, but it was for your own good.
Love,
Big Pharma
Some know God, some don’t.
It’s that simple.
What UTTER BS. It's been tested in a wide variety of clinical and observational studies world-wide on real human beings for almost 18 months now and been proven to be highly effective. "in a lab" -- what crap.
Thanks for that link. That is an ASTONISHING piece of work! I had not seen that before. Just bookmarked in my “COVID > Ivermectin” folder for future reference.
Couple of remarkable items of note from the summary:
• Administration with food, often not specified, may significantly increase plasma and tissue concentration. (a chart shows this).
• The evidence base is much larger and has much lower conflict of interest than typically used to approve drugs. (I had not heard this before)
Should have been the very first thing they did.
It would have prevented a lot of unnecessary deaths.
Yes, that is a good link to save. Actually, fantastic!
.
Amazing…over 3X blood concentration taken with food.
I’ve had a lot of medicines and supplements that say take 20 minutes before a meal or with food. I guess these pharmacokinetics must hold true for lots of them.
“While studies have shown ivermectin to inhibit virus replication in a lab, studies in people have been more limited and have not conclusively demonstrated the drug’s effectiveness or safety for the purpose of treating Covid-19”
BULL$HIT!
We probably ought to post that from time to time at the appropriate threads. Quite of few people here are taking Ivermectin and would find that info helpful.
A few months ago I was permabanned from a site for simply posting a video of a doctor testifying before the Senate regarding his group’s success with treating Covid victims with Ivermectin.
The reason: “Posting conspiracy theory crap.”
Something has been swirling around the back of my mind, and I haven’t seen anybody else publicly address it.
By using Ivermectin, an antiparacitic, are they saying that covid is a paracite?
Quinine is also an antiparacitic remedy.
So why does it take a change in dna to supposedly cure it?(ie the vaccines), but the antiparacitics work better?
The current narrative doesn’t add up.
Ivermectin was originally developed to fight parasites and it was very good at it. So good that it is in the WHO model list of essential medicines.
,
But a bonus was discovered during research done to use repurposed drugs to fight the Coronavirus.
Ivermectin binds to and destabilises the Impα/β1 heterodimer thereby preventing Impα/β1 from binding to the viral protein (bottom) and preventing it from entering the nucleus. This likely results in reduced inhibition of the antiviral responses, leading to a normal, more efficient
antiviral response.
See here for details:https://www.sciencedirect.com/science/article/pii/S0166354220302011#:~:text=Ivermectin%20binds%20to%20and%20destabilises,normal%2C%20more%20efficient%20antiviral%20response.
Here is a more detailed description of Ivermectin’s mechanism of action against the Coronavirus:
https://www.nature.com/articles/s41429-021-00430-5
TITLE:
The mechanisms of action of Ivermectin against SARS-CoV-2: An evidence-based clinical review article
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