Posted on 06/05/2021 3:24:15 PM PDT by nickcarraway
COVID-19 continues to claim lives around the world and is infecting millions more. Although several vaccines have recently become available, making significant strides towards preventing COVID-19, what about the treatment of those who already have the infection? Vaccines aren't 100% effective, highlighting the need—now more than ever—for effective antiviral therapeutics. Moreover, some people can't receive vaccines due to health issues, and new variants of SARS-CoV-2, the virus that causes COVID-19, that can penetrate vaccine-conferred immunity, are being reported, indicating that we need to think beyond prevention.
Given this need, a team of researchers based in Japan, the US, and the UK launched a project to develop effective therapeutics. This team included several researchers based at Tokyo University of Science: Visiting Professor Koichi Watashi, Dr. Hirofumi Ohashi, Professor Shin Aoki, Professor Kouji Kuramochi, and Assistant Professor Tomohiro Tanaka. Their goal was clear and simple: finding a cure for COVID-19.
To achieve this goal, the researchers first established an experimental system for screening drugs that may help to control infections. This system used a type of cells called VeroE6/TMPRSS2 cells, which were manipulated to efficiently be infected with and produce SARS-CoV-2. "To determine whether a drug of interest could help combat infection by SARS-CoV-2, we simply had to expose VeroE6/TMPRSS2 cells to both the drug and SARS-CoV-2 and then observe whether the drug's presence served to hinder the virus's efforts to infect cells," explains Professor Watashi.
The researchers used this experimental system to screen a panel of drugs that are already approved for clinical use, including drugs like remdesivir and chloroquine that have already being approved or are being trialed as treatments for COVID-19. In an exciting outcome, the researchers found two drugs that provided effective SARS-CoV-2 suppression: cepharanthine, which is used to treat inflammation, and nelfinavir, which is approved for the treatment of HIV infection.
Cepharanthine inhibited the entry of the virus into cells by preventing the virus from binding to a protein on the cell membrane, which it uses as a gateway. In contrast, nelfinavir worked to prevent the virus from replicating inside the cell by inhibiting a protein that the virus relies on for replication. Given that these drugs have distinct antiviral mechanisms, using both of them together could be especially effective for patients, with computational models predicting that combined cepharanthine/nelfinavir therapy can hasten the clearance of SARS-CoV-2 from a patient's lungs by as few as 4.9 days.
So, does this mean we will be seeing these new drugs in COVID-19 treatment centers? Of course, the drug duo isn't ready to be rolled out into healthcare systems just yet. These findings justify further research into the clinical potential of cepharanthine/nelfinavir therapy, and only following this can we say for sure that it is useful and helpful.
Nevertheless, given the ongoing nature of the COVID-19 pandemic and the ever-increasing death toll, the development of cepharanthine/nelfinavir therapy may provide clinicians and patients with a much-needed new treatment option.
Already an effective ‘drug duo’ : HCQ and Ivermectin.
One silver lining of this Chicom bioweapon may well turn out to be that with the money and research poured into stopping COVID if and when a more dangerous virus shows up, effective vaccines and anti-virals should be available much faster.
Remember this
The government; the medical industry ; the pharmaceutical industry - want you to be dependent on them
All of their solutions always require you to get help from them !
permission from them
a prescription from them
or something from them
You are in charge of your own health !!
you make decisions every day that are going to determine whether you’re a healthy person or not a healthy person
I’m gonna tell you right here and right now that the silver ion silver is the most affective antibiotic and antiviral for human beings on planet earth
Colloidal silver
The government the medical industry knows this - and silver is in tens of thousands of medical products
The secret is you can make your own silver , in a glass , in your own kitchen , using off-the-shelf materials that are commonly available
and you will never ever need a doctor or pharmacist or any drugs that you have to purchase from the industry. For fighting PATHOGENS
Now , if you break a bone , have severe pain , things like that - the medical industry is fabulous
But in terms of fighting illness created by pathogens in the environments there is nothing better than silver. And silver is FREE
The vaccine industry , on the other hand , is pure evil
Fortunately for those of us that I’ve been following them for decades and all the lives that they’ve ruined they’re really exposing themselves this time
Of course all the lemmings and sheep the Democrats are lining up for their Covid shot ; because they’re morons
Again let me get back to the main point
YOU ARE IN CHARGE OF YOUR OWN HEALTH.
My doctor is a little Italian from Calabria. He proscribes meatballs for everything. I’m not too healthy.
Inverse tin is working in India
FTA:
“...the development of cepharanthine/nelfinavir therapy may provide...”
Twitter and Faceplant a whole new set of reasons to fact-check, suspend, or ban you.
Would you rather be healthy or happy?
There is a ton of research going specifically into coronaviruses. I’m sure China is disappointed their virus family of choice for bioweapons is slowly being rendered less of a threat.
These two drugs are an anti-inflammatory and a protease inhibitor. Both of these are seeing a lot of activity in big pharma, including some trials in progress. Ivermectin has also been shown to act as a protease inhibitor, and that might be the process that makes it a possibly effective treatment for coronaviruses.
Inverse tin? Did auto correct fix that for you?
I relay on a bit of denial to answer that question. I did asked for a second opinion.
Don’t tell Tony or Cavuto.
That must be intended to mean something. Does it mean that lungs are cleared in 4.9 days? Does it mean that the lungs are cleared 4.9 days sooner that a baseline number of days established by a control group?
Probably neither.
You mean Ivermectin...I hope😆
The US didn’t organize a mass effort here to find workable thereputics.
Why?
Oh yeah, Fauci. The chicom mole.
The RAT mole
Computational models...
Unfortunately that is the same ‘logic/reasoning’ for HerrDoktor FauxiGates gain of function promotion and funding.
“We have to create a more virulent, lethal virus in order to know how to fight it when it gets out.”
I suppose. But, considering the success the CCP had in upending this country, having the ability to defend against another attack is unwanted, but useful nonetheless. They’ll do it again when useful considering no retribution is in the cards.
Lots of treatments in the pipeline these days. And with indications they can help with many other diseases.
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