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What We Know About the Effectiveness of the Johnson & Johnson COVID-19 Vaccine Is as Compared to the mRNA Vaccines
Healthline ^ | 05/27/2021 | Medically reviewed by Angela M. Bell, MD, FACP — Written by Jill Seladi-Schulman, Ph.D.

Posted on 05/29/2021 9:06:23 PM PDT by SeekAndFind

The Johnson & Johnson (J&J) vaccine is a single-dose vaccine that can help prevent COVID-19. It’s the third COVID-19 vaccine authorized by the Food and Drug Administration (FDA) for emergency use in the United States.

Large-scale clinical trials in several locations across the globe found that a single dose of the J&J vaccine was effective at preventing COVID-19. They found that the vaccine can also protect against several viral variants.

Below, we’ll break down everything we know so far about the efficacy of the J&J COVID-19 vaccine. Continue reading to learn more.

How effective is the Johnson & Johnson vaccine?

The efficacy of the J&J vaccine was tested in a clinical trial involving more than 40,000 people. The FDA reviewed this data, along with manufacturing information provided by Johnson & Johnson, when deciding to grant emergency use authorization.

The results from this clinical trial found that the J&J vaccine could protect against mild to moderate and severe to critical cases of COVID-19.

Let’s take a closer look.

Mild to moderate COVID-19

In most people, COVID-19 is a mild or moderate illness. Many individuals can recover from mild to moderate COVID-19 at home.

J&J vaccine’s efficacy for mild to moderate COVID-19 14 days after vaccination was:

Severe to critical COVID-19

The World Health Organization (WHO) estimates that 20 percent of people with COVID-19 experience a severe to critical illness that often requires hospitalization.

J&J vaccine efficacy for severe to critical COVID-19 14 days after vaccination was:

Additionally, individuals receiving the J&J vaccine were less likely to be hospitalized than those who didn’t receive the vaccine. In fact, the J&J vaccine was 93 percent effective at preventing hospitalization for COVID-19 14 days after vaccination and 100 percent effective 28 days after.

How long will the Johnson & Johnson vaccine protect you?

How long the J&J and Moderna vaccines will protect against COVID-19 is currently unknown. Research suggests that the Pfizer vaccine will offer protection for 6 months, but studies are ongoing.

Earlier clinical trials of the J&J vaccine found that a single dose of the vaccine produced a strong immune response in most people. Measurements taken 71 days later found that levels of antibodies remained stable or had increased.

Overall, more research is needed to determine how long the J&J vaccine will protect against COVID-19. It’s possible, but not certain, that a booster may be needed in the future.

How does the Johnson & Johnson vaccine’s efficacy compare with Moderna’s and Pfizer’s?

You may be wondering how the efficacy of the J&J vaccine stacks up against the other two COVID-19 vaccines authorized for use in the United States. These are the mRNA vaccines produced by Pfizer and Moderna.

Data from clinical trials of the Pfizer vaccine found an efficacy of 95 percent 7 days after the second dose. Clinical trial data of the Moderna vaccine reported an efficacy of 94.1 percent 14 days after the second dose.

These numbers may seem much higher than those of the J&J vaccine. However, it’s important to note that it’s not possible to make direct comparisons between the three COVID-19 vaccines. This is because the clinical trials:

The FDA notes that the only way to directly compare the efficacy of the three vaccines is to conduct a head-to-head clinical trial. This has not yet been done.

The CDC currently doesn’t recommend the use of one vaccine over another.

Does the Johnson & Johnson vaccine protect against asymptomatic COVID-19?

Preliminary data from the J&J vaccine clinical trial indicates that the J&J vaccine can protect against asymptomatic COVID-19. Asymptomatic means that a person doesn’t have symptoms but may still be able to spread the SARS-CoV-2 virus to others.

In the J&J vaccine clinical trial, 2,650 trial participants were tested using a COVID-19 antigen test 71 days after vaccination. This test identified 18 asymptomatic SARS-CoV-2 infections in the vaccinated group and 50 in the unvaccinated group.

Based on this data, researchers estimated that the efficacy of the J&J vaccine for preventing asymptomatic COVID-19 was at least 66 percent. This is comparable to the vaccine’s overall efficacy for preventing mild to moderate COVID-19.

The Pfizer and Moderna vaccines can also prevent asymptomatic COVID-19. Current research indicates that the vaccines can significantly reduce the rate of asymptomatic COVID-19.

How effective is the Johnson & Johnson vaccine against COVID-19 variants?

It’s completely normal for viruses to mutate. When this occurs, new variants can emerge.

So far, several different variants of the novel coronavirus have been identified. Some of these have caused concern amongst public health officials. This is because the variants may be more contagious or escape the immune response.

The J&J vaccine clinical trial can give us some indication of how effective the vaccine is against these variants. This is because the trial was carried out at a time when viral variants were very common in some locations.

At the time of the trial, 95 percent of sequenced COVID-19 cases in South Africa were caused by the B.1.351 variant. The efficacy of the J&J vaccine at this location was 52 percent for mild to moderate COVID-19 and 73.1 percent for severe to critical COVID-19.

Similarly, in Brazil, 69 percent of the sequenced COVID-19 cases were caused by the P.2 lineage. The efficacy of the J&J vaccine in Brazil was 66.2 percent for mild to moderate COVID-19 and 81.9 percent for severe to critical COVID-19.

Demographics of the Johnson & Johnson vaccine clinical trial

Compared with the two mRNA vaccines, the clinical trial of the J&J vaccine included more people of racial or ethnic backgrounds that may be at a higher risk of COVID-19. This is important, as it helps give researchers a better idea of the vaccine’s efficacy across many different racial and ethnic groups.

The table summarizes the demographics of the three vaccine trials.

Johnson & JohnsonPfizer-BioNTechModerna
White62.1%82%79.4%
Hispanic or Latino45.1%26.2%20%
Black or African American17.2%10%9.7%
Native American8.3%less than 1%less than 1%
Asian or Asian American3.5%4%4.7%
Pacific Islander or Native Hawaiian0.3%less than 1%less than 1%
Multiple races5.4 percentNot reportedNot reported

Should some people avoid taking the Johnson & Johnson vaccine?

People who experienced a severe or immediate allergic reaction to any of the ingredients in the J&J vaccine should not receive the J&J vaccine. The information sheet for recipients and caregivers includes a list of the ingredients.

The CDC notes that female adults under the age of 50 should be aware of the risk of TTS following J&J vaccination. If TTS is a concern, the other COVID-19 vaccines aren’t associated with this very rare side effect.

The bottom line

The J&J vaccine is the third COVID-19 vaccine authorized by the FDA for emergency use in the United States. It consists of a single dose that’s been found to be both safe and effective at preventing COVID-19.

Clinical trials found that the J&J vaccine can prevent many types of COVID-19. Its overall efficacy was 66.3 percent for mild to moderate COVID-19 and 76.3 percent for severe to critical COVID-19. Additionally, it provides 100 percent protection from hospitalization for COVID-19 28 days after vaccination.

The J&J vaccine can also protect against asymptomatic COVID-19, as well as some viral variants. It’s currently unknown how long the vaccine protection will last. A booster shot may be needed in the future.

The efficacy of the three authorized COVID-19 vaccines can’t be compared directly, as the trials took place at different locations and at different times in the pandemic. Currently, no one vaccine is recommended over the others.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid19; effectiveness; johnsonjohnson; vaccines

1 posted on 05/29/2021 9:06:23 PM PDT by SeekAndFind
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To: SeekAndFind

Plus, it’s the only one with a “no more tears” formula.


2 posted on 05/29/2021 9:14:01 PM PDT by OrangeHoof (Chinese communism will look different once the masks come off.)
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To: SeekAndFind

What we know. Propaganda asswipe. Is the vaxx industry lies and kills m

http://vaxtruth.org/

This is WAR FOR HUMANITY VERSUS GLOBAL TYRAANY


3 posted on 05/29/2021 9:33:40 PM PDT by Truthoverpower (Arizona !!!! Now the TRUMP TRAIN is getting back on TRACK ! TRUTH! FREEDOM ! LIBERTY! )
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To: OrangeHoof

No more tears? More like dead within 2 years.


4 posted on 05/29/2021 9:34:23 PM PDT by The Fop (God Bless Donald Trump, Frank Sinatra, Joan Rivers, and the Fightin' Rat Pack Wing of the GOP)
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To: SeekAndFind

Well since Ivermectrin is 100% effective, if someone wanted to really have a robust anti covid 19 immunity the best scientific method would be to simply ignore the vax.

If they caught Covid, take Ivermectrin and you are immune for life. If they do not catch Covid the are already immune.

Ivermectrin costs 6 bucks, and does not have a death rate like the vax does.

But covid was never about science.


5 posted on 05/29/2021 10:10:29 PM PDT by American in Israel (A wise man's heart directs him to the right, but the foolish mans heart directs him toward the left.)
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To: SeekAndFind

https://rumble.com/vhp8e1-massive-world-renowned-doctor-blows-lid-off-of-covid-vaccine.html


6 posted on 05/29/2021 10:21:55 PM PDT by 9YearLurker
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To: SeekAndFind

The aborted baby cells give JnJ that extra kick. Would love for the ones who got it try and explain it away on judgement day


7 posted on 05/29/2021 11:01:02 PM PDT by roving
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To: roving

“The aborted baby cells give JnJ that extra kick. Would love for the ones who got it try and explain it away on judgement day”

Pfizer and Maderna both used the fetal cell line HEK-293 in the confirmation phase to ensure the vaccines work.

So there is no escaping going to hell for the going on one billion people vaccinated world wide so far??


8 posted on 05/30/2021 2:54:31 AM PDT by DAC21
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To: SeekAndFind
There are legitimate concerns with overstimulated immune systems with the vaxes. But there are many worse cases with the disease and 1% die. And of course you can take actions to avoid getting the disease so everyone has to evaluate their own risk of that. In general older people will be better off getting vaccinated and younger better off without. But there's no hard and fast rule.

~~~~~~~~~~~~~~~~~~

There are medication protocols that cut the risk of death among the most vulnerable by 85%.

Since those infected and treated with medications then have immunity, that overall treatment outcome is MUCH BETTER than the 'vaccinated' who only tested for 14 days to 2 months for which they claimed 'efficacy'. Those vaccinated can still get infected during the trial period as well as immediately following the trial period. 

So 10K and they are intentionally not counting all the other break through infections because the CDC is only counting hospitalization/death 'breakthrough.'

C.D.C. Will Not Investigate Mild Infections in Vaccinated Americans (msn.com)

And then the risks for Covid 'vaccines' are worse than they are for HCQ and Ivermectin, type protocols.

There was never a need to get 'vaccinated' when safe, effective medications have been available all along.

Early Treatment Protocols (Collection of Covid-19 resources, treatment and prophylactic protocols)

9 posted on 05/30/2021 3:25:13 AM PDT by ransomnote (IN GOD WE TRUST)
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To: SeekAndFind
"In fact, all major vaccine makers (save Moderna) have paid out tens of billions of dollars in damages for other products they brought to market when they knew those products would cause injuries and death--see VioxxBextraCelebrexThalidomide, and opioids as a few examples.
10 posted on 05/30/2021 3:28:44 AM PDT by ransomnote (IN GOD WE TRUST)
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To: SeekAndFind
More about the J&J:

German Scientists Find How Broken Parts Of COVID-19 Vaccines Mutate To Trigger Blood Clots
greatgameindia.com ^ | May 28, 2021 | greatgameindia.com

Posted on 5/30/2021, 3:44:13 AM by ransomnote

11 posted on 05/30/2021 3:45:09 AM PDT by ransomnote (IN GOD WE TRUST)
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To: roving

Oh, please. People who received the J&J vaccine are unaware of your claim of aborted cells, if that is actually true.


12 posted on 05/30/2021 3:58:39 AM PDT by EnquiringMind
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To: OrangeHoof

Maybe J%J should have stuck to Band-Aids and baby shampoo instead.


13 posted on 05/30/2021 4:12:29 AM PDT by princeofdarkness ( )
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To: SeekAndFind

Thanx for posting


14 posted on 05/30/2021 4:47:47 AM PDT by thinden
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To: EnquiringMind

Hubby got it, and I can tell you he didn’t know, didn’t want to know, just paranoid I have to have it. In 20 yrs in USN he took so many vaccines it is second nature. To get paid during Flu season they went to the Sick Bay to get Flu shot and paycheck. Then 20 yrs teaching JR COLLEGE.

BTW; BIRD FLU IS BACK! RUN OUT AND GET IT. NOT ME, I REACT TO THEM. I SURE AS H DON’T WANT TO END UP IN THE CRAP HOSPITALS IN MEMPHIS, TN. CRIME CAPITOL OF THE STATE.

He had his Pneumonia shot 2 weeks before. Doc says you need it he gets it.
I told the Gastro to shove his last Colon Screen where the sun didn’t shine, remove the 3 pre-CANCER ESOPOGUS BARRETT’S SPOTS FIRST, BEFORE THEY BECOME CANCER.

These Godless college kids don’t care either. Nor do their parents, FEAR GINNED BY MSM, POLS, DOCS, NURSES, SPORTS IDIOTS.


15 posted on 05/30/2021 6:52:13 AM PDT by GailA (Constitution vs evil Treasonous political Apparatchiks, Constitutional Conservative.)
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To: princeofdarkness

Actually, I think J&J is probably the one I would want if I’m forced into vaccination. They aren’t monkeying with my DNA and they aren’t on the same level as a Pfizer or AstraZeneca in terms of questionable ethics.

That’s not a great endorsement but I’m really put off by this RNA stuff. These things get rushed into production without knowing the long-term effects. I’m highly suspicious of that.


16 posted on 05/30/2021 10:12:11 AM PDT by OrangeHoof (Chinese communism will look different once the masks come off.)
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