Posted on 05/01/2021 8:48:25 PM PDT by SeekAndFind
Novavax's shot could become the next coronavirus vaccine in the U.S. arsenal, potentially jumping ahead of AstraZeneca in the line for U.S. authorization, Politico reports.
Why it matters: The vaccine proved to be just as effective as Pfizer and Moderna's mRNA vaccines in a U.K. clinical trial, and could become a crucial tool in the global vaccination effort.
Between the lines: Novavax has never brought a product to market before, and began last-state clinical trials months after some of the other candidates.
But AstraZeneca's rollout has been plagued by a series of public relations mishaps, and it — along with Johnson & Johnson's shot — has been linked to rare but serious blood clots. J&J is also facing production concerns in the U.S.
By the numbers: Novavax has committed to provide 100 million doses of its shot to the U.S. later this year, and has promised to provide 1.1 billion doses to low- and middle-income countries.
The U.S. probably doesn't need any more vaccines. But the rest of the world does.
What we're watching: Whether the company can ramp up manufacturing enough to meet its ambitious goals.
"If that [would] face a challenge, it would be a big setback for COVAX in terms of delivering doses in 2021," Mesfin Teklu Tessema, senior director at the International Rescue Committee and a member of a civil society working group for COVAX, told Politico.
(Excerpt) Read more at news.yahoo.com ...
Does it use mRNA technology? If so I will not be taking it.
The Novavax vaccine works like other vaccines by teaching the immune system to make antibodies to the coronavirus spike protein.
Researchers inserted a modified gene into a virus, called a baculovirus, and allowed it to infect insect cells.
Spike proteins from these cells were then assembled into nanoparticles which, while they look like coronavirus, cannot replicate or cause Covid-19.
These nanoparticles are then injected into the body via the vaccine where the immune system mounts an antibody response.
If the body encounters coronavirus in the future, the body is primed to fend it off.
Who owns Novavax and where is the vaccine made? (thesun.co.uk)
Does it use mRNA technology? If so I will not be taking it.
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The DNA products (astrazeneca, J&J) have severe problems too.
No... I am one of their “Lab Rats” and joined their trial due to their methodology...
I’m sure there are people who will sign up to get all of them.
It does not use mRNA technology.
Yeah, no mRNA. They’ll have to use something else to scare people out of getting that vaccine. My guess is they’ll focus on the adjuvant—Matrix-M.
If you get the Matrix shot, you’ll become a battery for the machines!
DO YOU WANT TO BECOME A BATTERY??!!
“Novavax’s patented saponin-based Matrix-M adjuvant has demonstrated a potent and well-tolerated effect by stimulating the entry of antigen-presenting cells into the injection site “
uh huh ... similar technology resulted in an epidemic of feline hyperthyroidism and fatal injection site sarcomas for feline vaccinations ...
RE: Does it use mRNA technology? If so I will not be taking it.
The short answer is NO.
See here:
Like most of the Covid-19 vaccine candidates, the Novavax candidate requires two shots spaced three weeks apart. But candidate NVX-CoV2373 actually works differently than the other vaccines that have made it this far. It’s a protein subunit vaccine, which means that it uses a lab-made version of the SARS-CoV-2 spike protein. This spike protein alone can’t make anyone sick. But to make sure that the body still generates the protective antibodies against it, Novavax has inserted an ingredient called an adjuvant, which acts as a hypeman for the immune system to signal it to spring into action.
Novavax’s subunit vaccine approach is a tried and true method for generating effective vaccines. Modern flu vaccines, HPV vaccines, and HepB vaccines all use a similar approach. But because these vaccines have multiple components—the spike protein and the adjuvant—they typically take longer to make than other vaccine types. That makes it surprising that 20-year-old Novavax, which has never produced a vaccine that’s reached the public before, made it to late-stage clinical trials so quickly.
But, What if the spike protein alone can make you sick?
Then having a few non-replicating ones in an isolated part of the arm is preferable to having an active infection with self-replicating pathogens creating billions of copies of themselves and flooding your entire body with the spike proteins.
No. Novavax uses select viral proteins, an approach that is thought to be safer than even the traditional inactivated virus method.
Since Covid-19 has never been isolated in the lab or Gene sequenced, how did they develop an artificial Spike Protein in the Lab? All based on computer models I would assume.
New reports out that the Spike Protein can and may cause increase in Strokes and Heart Attacks.
Also the Novavax vaccine is being rushed through also. Not one that I would take.
It’s been isolated and sequenced. Here’s just one instance of that.
How did it go? Is it one shot or two? Did you have any side effects?
I've been interested in Novavax because it is not mRNA and seems to be promising.
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