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COVID-19 reduces fertility in men, study suggests
Healio ^ | Jan 2021 | Janell Miller

Posted on 04/13/2021 9:35:32 AM PDT by CondoleezzaProtege

COVID-19 may negatively affect sperm quality and reduce fertility in men, and the magnitude of that effect may depend on the severity of disease, researchers reported.

“Little is known about the virus-host interaction of COVID-19 in sperm cells,” Behzad Hajizadeh Maleki, a doctoral student and research assistant in the department of psychology and sports science at Justus Liebig University in Germany, and Bakhtyar Tartibian, PhD, of the physical education and sports science department at Urmia University in Iran, wrote in in the journal Reproduction.

“We are the first to address the connection between changes in multiple seminal biomarkers and reproductive function in male patients recovering from COVID-19,” they said.

Hajizadeh Malekiand Tartibian conducted a prospective, longitudinal cohort study of 84 men with laboratory-confirmed COVID-19 and 105 men without the disease in Iran. The researchers analyzed changes in angiotensin-converting enzyme 2 (ACE2) activity, markers of inflammation and oxidative stress, apoptotic variables and semen quality, all of which were evaluated at 10-day intervals for up to 60 days.

Most of the men in the study were in their 30s and “differed substantially” in body weight, body fat percent and BMI, according to the researchers. Among those with COVID-19, all but one had either a moderate, severe or critical form of the disease. A urology expert confirmed that all the men were fertile in the study. Men with COVID-19 were treated with corticosteroids and/or antiviral therapies.

The researchers reported that at baseline and during subsequent follow-ups, the COVID-19 group showed significantly higher levels of seminal plasma ACE2 enzyme, as well as higher levels of both pro- and anti-inflammatory cytokines in sperm — including interleukin (IL) 1-beta, IL-6, IL8, IL-10, transforming growth factor (TGF)-beta, tumor necrosis factor-alpha, and interferons alpha and gamma. They also had higher levels of reactive oxygen species and lower superoxide dismutase activity compared with healthy controls.

The markers of inflammation and oxidative stress in sperm cells of men with COVID-19 were increased by more than 100% compared with controls, according to the researchers. Sperm concentration was reduced by 516%, mobility by 209% and sperm cell shape was altered by 400%.

Although these effects tended to improve over time — representing “a transient state of male subfertility like those with oligoasthenoteratozoospermia” — the researchers wrote they remained “significantly and abnormally higher in the COVID-19 patients, and the magnitude of these changes were also related to disease severity.”

In an interview with Healio Primary Care, Hajizadeh Maleki recommended that couples who want to have children should proceed with caution.

“Female partners of men recovering from the disease should decide not to conceive until a specialist carefully examines and certifies their fertility status,” he said.


TOPICS: Health/Medicine
KEYWORDS: conception; covid; fertility; pregnancy; sperm; testosterone
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To: BiglyCommentary

“There have been stories like this posted on FR how climate change will do the same thing, i.e lower fertility...Same fear mongering garbage.”

You may want to check on fertility numbers over the past 20 years, and not just regarding rich whites.


21 posted on 04/13/2021 10:19:47 AM PDT by BobL (TheDonald.win is now Patriots.win)
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To: CondoleezzaProtege

Oh, thank heaven - I already have six kids and my wife’s looking hot!


22 posted on 04/13/2021 10:20:31 AM PDT by Chainmail (Remember - that half the people you meet are below average intelligence)
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To: CondoleezzaProtege

So what about men taking the experimental vaccines. How is their fertility affected?


23 posted on 04/13/2021 10:36:22 AM PDT by FR_addict
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To: FR_addict
So what about men taking the experimental vaccines. How is their fertility affected?

I’m curious also. Re: women....There are already studies starting up about menstrual period irregularities due to vaccines (as well as Covid itself.)

24 posted on 04/13/2021 10:49:06 AM PDT by CondoleezzaProtege
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To: stars & stripes forever

That was due to the “medicine”, not the disease. Totally different story.


25 posted on 04/13/2021 11:00:53 AM PDT by BiglyCommentary
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To: BobL

What do a general decline in fertility rates have to do either climate change or covid? Answer... wait for it... NOTHING.


26 posted on 04/13/2021 11:02:58 AM PDT by BiglyCommentary
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To: CondoleezzaProtege

Sounds like they might be prepping us for infertility issues. I believe these issues will be caused not by the virus, but by the vaccines. They’ll just blame the virus.

Tell the lie long enough...


27 posted on 04/13/2021 11:09:31 AM PDT by Mathews (It's all gravy, baby!)
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To: CondoleezzaProtege

In “Children of Men”, a massive “flu” pandemic hit. It killed a lot of kids. And then no one could have kids afterward ...


28 posted on 04/13/2021 12:06:14 PM PDT by tbw2
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To: stars & stripes forever

Where are the studies on what the experimental vax’s do to fertility levels?

Oh, yeah....we’ve already seen the miscarriage articles and renewed caution for younger women NOT to take the ‘vax’s’, already.


29 posted on 04/13/2021 12:09:03 PM PDT by Jane Long (America, Bless God....blessed be the Nation 🙏🏻🇺🇸)
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To: Mathews; metmom; bagster; SecAmndmt

Sounds like they might be prepping us for infertility issues. I believe these issues will be caused not by the virus, but by the vaccines. They’ll just blame the virus.

Tell the lie long enough...


Great point.


30 posted on 04/13/2021 12:10:15 PM PDT by Jane Long (America, Bless God....blessed be the Nation 🙏🏻🇺🇸)
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To: FR_addict
So what about men taking the experimental vaccines. How is their fertility affected?

Both men's and women's fertility will be affected.

Reproduction is the target, killing off the elderly is just a side benefit for the derps.

#WakeUpPeople


31 posted on 04/13/2021 12:18:27 PM PDT by bagster ("Even bad men love their mamas".)
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To: Mathews
Sounds like they might be prepping us for infertility issues. I believe these issues will be caused not by the virus, but by the vaccines. They’ll just blame the virus.

And we have a winner!

The covid and 'variants' will give them license to put anything they want into our bodies. And our children's bodies.

NEVER trust the derp state.

EVER.


32 posted on 04/13/2021 12:20:54 PM PDT by bagster ("Even bad men love their mamas".)
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To: Mathews

👍 Yep. Intended population control through the drug.


33 posted on 04/13/2021 12:43:33 PM PDT by TianaHighrider (God bless President Trump. Prayers for PDJT and his loyal supporters.)
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To: CondoleezzaProtege

Well, I guess now we can all f**k with wild abandon.


34 posted on 04/13/2021 1:34:08 PM PDT by ought-six (Multiculturalism is national suicide, and political correctness is the cyanide capsule. )
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