IN THE MEANTIME:
THE HAGUE, Netherlands (AFP)— The EU’s medicines regulator on Monday advised against using the anti-parasite drug ivermectin for coronavirus outside clinical trials, despite headlines touting it as a miracle cure.
Facebook posts and articles endorsing ivermectin have proliferated in Brazil, France, South Africa and South Korea as governments around the world struggle with vaccination programmes.
“EMA has reviewed the latest evidence on the use of ivermectin for the prevention and treatment of Covid and concluded that the available data do not support its use for COVID outside well-designed clinical trials,” the European Medicines Agency said.
The Amsterdam-based agency said it had not received any application for authorisation of the drug, which has long been used to treat parasites such as head lice and for river blindness in sub-Saharan Africa.
Further tests were needed to see if it was effective against coronavirus, the EMA said.
Lab tests had found ivermectin could block replication of the virus that causes COVID-19 “but at much higher ivermectin concentrations than those achieved with the currently authorised doses,” the regulator added.
Toxic effects at those higher doses could not be ruled out, it said.
Literally trillions of doses have been used world wide since its invention.
100% of the 48 studies to date report positive effects (23 statistically significant in isolation). Random effects meta-analysis for early treatment and pooled effects shows an 79% reduction, RR 0.21 [0.10-0.44], and prophylactic use shows 89% improvement, RR 0.11 [0.06-0.23]. Mortality results show 76% lower mortality, RR 0.24 [0.14-0.42] for all treatment delays, and 84% lower, RR 0.16 [0.04-0.63] for early treatment.
•100% of the 25 Randomized Controlled Trials (RCTs) report positive effects, with an estimated 68% improvement, RR 0.32 [0.21-0.49].
•The probability that an ineffective treatment generated results as positive as the 48 studies to date is estimated to be 1 in 281 trillion (p = 0.000000000000004).
https://ivmmeta.com/
It is amazing to me how the regulators have streamlined the regulations for the novel vaccines, yet they seem to want more trials and testing on tried and true drugs like Ivermectin and Hydroxychloroquine.