Posted on 03/12/2021 2:40:12 PM PST by ConservativeMind
University of Texas Medical Branch at Galveston researchers have discovered that a form of vitamin B1 could become a new and effective treatment for one of the world's leading causes of blindness.
Scientists believe that uveitis, an inflammation of the tissue located just below the outer surface of the eyeball, produces 10 to 15 percent of all cases of blindness in the United States, and causes even higher rates of blindness globally. The inflammation is normally treated with antibiotics or steroid eye drops.
In a paper appearing in the May issue of the journal Investigative Ophthalmology and Visual Science, however, the UTMB researchers describe striking results achieved with benfotiamene, a fat-soluble form of vitamin B1. In their experiments, they first injected laboratory rats with bacterial toxins that ordinarily produce a reaction mimicking uveitis. When those rats are fed benfotiamene, they fail to develop any signs of the inflammatory disorder.
"Benfotiamene strongly suppresses this eye-damaging condition and the biochemical markers we associate with it," said UTMB associate professor Kota V. Ramana, senior author of the study. "We're optimistic that this simple supplementation with vitamin B1 has great potential as a new therapy for this widespread eye disease."
The researchers' data shows benfotiamene works by suppressing the activation of a crucial signaling molecule called NF-kappa B, which is normally triggered by the stress caused by infection. Shutting down NF-kappa B, they said, prevents the runaway production of inflammatory proteins that generates uveitis.
Benfotiamene's low cost, rapid absorption by the body and lack of negative side effects make it an ideal candidate for uveitis prevention, according to Ramana.
(Excerpt) Read more at sciencedaily.com ...
So could this prevent Appaloosa horses from going blind? I see so many of them on pet rescue pages, virtually all of them blind from uveitis.
is there a simple blood test for this disorder?
I keep getting something. Tested negative for viral pink eye.
I would expect the supplement is harmless to most animals, but it would be best to check with a vet.
It’s interesting you mentioned large animals, because you can buy this in bulk:
https://purebulk.com/products/benfotiamine
An eye exam might find it, depending on the form:
https://www.mayoclinic.org/diseases-conditions/uveitis/symptoms-causes/syc-20378734
It is also used for diabetic retinopathy, neuropathy, and nephropathy and for Alzheimer’s.
It is a B vitamin, but in many countries, it is sold as a drug.
here are some blood tests..which cover a lot of things
https://www.reviewofoptometry.com/article/practical-pearls-for-managing-anterior-uveitis
in my recent hellish experience of dealing with medical profession somehow I doubt whatever eye doctor I choose would be willing to do those tests
Heck, I just had a idiot dermatologist tell me psoriasis has nothing to do with the immune system.
Sometimes it is cheaper to just order the tests you want from Directlabs.
But next time I get it I guess I will head to the eye doctor. One of those fast clinics just gave me some kind of antibiotic
Oh wow it's a thiamine prolog. I'll be getting some of this.
My wife and I have both ordered from Direct Labs.
You can know more than your doctors, if you keep up on the new information that wasn’t taught in school to them.
Yep. There are coupon codes that float around. I think I usually find them at www.retailmenot.com
Also worth noting…
“Thiamine in its fat-soluble form (benfotiamine) is literally curing Alzheimer’s disease as evidenced in brain scans.”
https://pubmed.ncbi.nlm.nih.gov/27696179/
Also, macular degeneration…
https://knowledgeofhealth.com/ignored-vitamin-cure-for-macular-degeneration/
life extension has it. i use them for some stuff
https://www.lifeextension.com/search#q=benfotiamine&t=coveo4A2453FD
I did see where it could raise blood pressure but didnt click on the info so need to go back and loo
Now if they can only do something to reverse glaucoma...
I wish there was something for dog cataracts.
:(
NOTE:
“ Magnesium is an essential co-factor with thiamine. The lack of magnesium may render supplemental thiamine useless.”
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