People Who Recovered From COVID-19 Should Receive Only 1 Dose of the mRNA Vaccine: Study

Amid reports of vaccine shortages occurring around the world, a new study (pdf) suggests that people who have already had COVID-19 should get only one shot of the mRNA vaccine to avoid possible unnecessary adverse reactions and free up supplies for those who need it more.

The study, which hasn’t been peer-reviewed, evaluated vaccine reactions after receiving the first dose in 231 individuals—83 with a past infection of the CCP (Chinese Communist Party) virus and 148 who had never had an infection.

Researchers found that both groups equally reported experiencing pain, swelling, and redness at the injection site at the time of vaccination, which improved in a couple of days. However, people with a prior infection experienced more severe systemic reactions—fever, headache, chills, muscle or joint pain, and fatigue—than those who had never been infected.

“We also noted that vaccine reactogenicity [expected reactions] after the first dose is substantially more pronounced in individuals with pre-existing immunity akin to side-effects reported for the second dose in the phase III vaccine trials [of both Pfizer-BioNTech and Moderna],” the researchers stated.

A severe systemic reaction to a vaccine “prevents daily activity,” according to the Food and Drug Administration (FDA).

Overall, there was a higher report of local and systemic adverse reactions in the vaccine group compared to placebo group in both the Moderna (pdf) and the Pfizer-BioNTech (pdf) phase 3 studies that continue to collect data on vaccine safety and efficacy.

The study also looked at immune system’s response to the vaccines in 109 people: 41 who had recovered from COVID-19 and 68 who’ve never had the disease, and found those in the recovered group had “10-20 times higher” antibody levels than those who had never been infected.

More studies are needed to further investigate the study’s findings due to the small number of participants.

What’s in it for them, then p, that they are still pushing for people to be vaccinated?

Sure, obviously the money, but considering how little I trust any government or big pharma these days, there has to be more to it.

RE: Its not additive, the mRNA platform demonstrated T-cell immunity immunity (Memory immunity) at about 8 weeks.

OK, if the body will gain Memory immunity, meaning it “remembers” the invader, will this memory last a lifetime?

As an analogy, I remember my first girlfriend from 40 years ago and saw her after 40 years. Still remember her. Is this the same kind of memory?

Second question, will this memory immunity only be good for one variant of the virus? That is, do they need to develop another vaccine for every new variant?

I might remember my girlfriend from 40 years ago, but if she has a sister who looks closely like her, I am not sure I will recognize her.

Coronavirus immunity, mainly based on animal studies, has generally been taken as a matter of months. And you have to differentiate between t-cell and antibody immunity.

One thing most people don’t realize is that additional cv infections tend to sensitize the immune system and result in subsequent illnesses being worse. This is why the booster shot is being linked to a greater degree of side effects. In an extreme case you get sensitization to an extreme degree, such that a cytokine storm occurs and possibly death. This was seen in animal studies 15 years ago. This is one reason I don’t want the vaccine: more immunity ==> possibly fatal reaction to an otherwise moderate illness. Also called Antibody-Dependent Enhancent (ADE).

Its a little more complex than that. There are many types of T - cells, T-helper, Memory cells, and IIRC NK cells (natural killer T-lymphocytes). Its been a long time since I took immunology so I am a little out on a limb here, fair warning, but the long and the short of it, is that the T cells that have memory surveil the body for an infection it recognizes (Ie you girlfriend from 40 years ago). It is “smart” enough, or genetically programmed to delineate between your girlfriend and sister. So when it sees your GF sister, it has no reaction, when it sees your GF it becomes — I suppose by analogy — aroused. It interacts with other members of the immune system to crank out antibodies quickly and quell any infection before it takes hold.

I do not remember exactly what cell does what, I think the CD 8+ cells are memory cells and the CD4+ are the helper. YMMV on this last statement. I would have to dos off my immunology and microbiology books and study a couple nights to again pass the test on this.

“How long does this immunity after infection last?”

It seems nobody knows. For the common cold, you DO get immune to the virus that caused the infection. But there are more than 200 viruses that cause the common cold and you will rarely face the same one twice. Most of the cold viruses are in four families:
• Rhinovirus
• Coronavirus
• RSV
• Parainfluenza

BUT, there are also a lot of viruses that haven’t been identified yet. It’s estimated that 20%-30% of colds in adults are caused by these “unknown” bugs.

Not for any infection — specific to the coronavirus antigens. Many papers out there; manufacturers of vaccine are trying to minimize the probability by excluding certain adjuvants and other bio components known to exacerbate this. If the vaccine works so well there is no illness or little illness that’s great. But ADE is a known possibility and affected all or nearly all lab animals in a particular study when exposed to a significantly mutated cv.

Example read:

https://www.nature.com/articles/s41564-020-00789-5

“Data from the study of SARS-CoV and other respiratory viruses suggest that anti-SARS-CoV-2 antibodies could exacerbate COVID-19 through antibody-dependent enhancement (ADE).”

Except it really is not a vaccine. It has no strands of Covid 19 within it. It is what they call a general immunity booster.

I do not need a vaccination, not for the flu which gives approximately “35% coverage, but lessens the symptoms if you do get the flu.” If you have a compromised immune system, a vaccination will do little to ramp it up. You are just as likely to get sick from the vaccine, as from the flu. I assume the covid shot is sketchier than that.

Plus, I tested positive for the Vid, was sick for two plus weeks, but survived. I am immune to this strain for life, if I remember my biology. Just like Measles, I am not getting those again either.

“Because there is no significant data if a previous infection promotes long term immunity. The vaccine can act as a booster shot.”

And what significant information is there that says the vaccine can act as a booster shot or produces better immunity than having had the virus?

Also note that the transgenic nature of the vaccine has zero track record because the mRNA method is making its debut as a vaccine - it has been used to kill a lot of animals by making them susceptible to cancers, etc., and has caused “escape” problems when used to make “better” crops - you, know, tomatoes that taste like crap but which last longer on the shelf, etc.

You might want to buff up on transgenic agents before making such definitive statements.

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