Posted on 12/19/2020 1:06:03 PM PST by SeekAndFind
Published: November 27, 2020
This week, the latest US national antibody data covering the period from September 7 to September 24 has been published. With the exception of a few northeastern states (notably New York), most US states still had an antibody seroprevalence below 10% or even below 5% (see charts below).
These are very low antibody levels. Until early October, the US counted about 300,000 excess deaths, of which about 200,000 deaths were associated with covid, according to the CDC. Of these, about 82,000 or 41% occurred in care homes, according to the LTC covid-19 network.
It is clear that covid in the US is a particularly serious disease, most likely due to the high levels of pre-existing metabolic conditions (i.e. diabetes, obesity and cardiovascular disease).
Until a safe and effective vaccine becomes available, the most important measure for high-risk people is early outpatient or even prophylactic treatment based on the protocol developed by the US Frontline Covid-19 Critical Care Alliance. Patients should contact their doctor.
In age-adjusted terms, overall US covid mortality will end up somewhere between the medium to strong flu pandemics of the 20th century. On the plus side, intubation and in-hospital mortality rates are markedly lower today than they were in spring, when many covid patients were directly and unnecessarily put on ventilators.
In Sweden, antibody seroprevalence in Stockholm has reached 31.6% by mid-November (up from 15% in October), which is by far the highest level of any Western capital (NYC reached about 25% by early summer), and is expected to significantly slow the local epidemic. However, other parts of Sweden may have reached only about 10 to 15%. Overall, Swedish mortality remains comparable to previous strong seasonal flu waves.
As previously mentioned, the actual prevalence of covid immunity may be somewhat higher than antibody values indicate, as commercial antibody tests may miss people who had an asymptomatic or mild covid infection. For instance, a highly sensitive antibody test developed by Northwestern University found a 20% seroprevalence in Chicago, instead of the previously assumed 5% to 10%.
US antibody data by state (July to September)
US antibody data by state and age group (July to September)
Bkmk
Google Images “Thalidomide Babies”
Take a quick look.
Another thing I only learned of because of “We Didn’t Start the Fire”
NOBODY SHOULD TAKE THAT DAMN VACCINE!!! Now that the AMA has reversed it’s policy on Hydroxychloroquin, it will cure. It’s too soon to put that crap in your body.
Resuming vaccinations tomorrow.
https://abc7chicago.com/covid-vaccine-effects-reaction-allergic/8892188/
It’s normal to pause and have a review to make sure things are as expected.
Definitely good to reflect back on mistakes from over 60 years ago when a drug was given in two clinical trials with tragic consequences.
Interesting though that if one is hunting for examples of problems in the drug review process in the US, one has to go back so many decades. If the process is so bad, no doubt there are plentiful recent examples of widespread problems, yes?
[[With the exception of a few northeastern states (notably New York), most US states still had an antibody seroprevalence below 10% or even below 5% (see charts below).These are very low antibody levels.]]
so the takeaway is that what Trump did worked far better than what liberals did in their states
“Until early October, the US counted about 300,000 excess deaths, of which about 200,000 deaths were associated with covid, according to the CDC.”
With 300,000 excess deaths and about 200,000 deaths with Covid on the death certificates, it is entirely possible that many or even most of the reported Covid deaths were not excess deaths. That is, many of the Covid deaths might have happened anyway, and many or most of the 300,000 excess deaths may have resulted from our reaction to Covid (missed diagnoses or delayed treatments for other diseases...) rather than from the disease itself.
That’s a particularly apt comparison. Here’s why:
Like a lot of compounds, Thalidomide is “chiral”, or “handed”. There are two versions of the molecule that are mirror images of each other. It’s thought that only one of these “mirror images” caused the problems with Thalidomide (there’s more to it, but that’s the gist.)
Drug companies and researchers are all over chirlatity today, largely as a result of the Thalidomide mess, but in 1957, when the drug was approved for use in Europe, they didn’t really pay any attention to “handedness”...it was known to exist, but not thought to be important. Now we know, and 10,000 people in Europe and the UK paid the price.
So, here’s the question: what don’t we know about mRNA used as a vaccine? This will be widely distributed, so we’ll know some of the answers to that pretty soon, and probably know a lot more after a couple of years.
For myself, I’m not at all unhappy that I won’t be in the first or second tranche of people eligible for the shot. I’ll evaluate the risks at that point after a few million folks have offered up their arms as test subjects.
ping
We know pretty much everything there is to know about mRNA. It’s a polynucleotide that occurs in every cell in every living organism, including humans. It functions as a “messenger” (hence the “m”) that transfers genetic information from the DNA in the nucleus to the ribosomes, structures in the cell where protein synthesis occurs. The mRNA consists of a sequence of nucleotide bases that are complementary to the ones in the DNA. Molecules of tRNA pair with the mRNA at the ribosome. Each tRNA is 3 bases long and each binds to a specific amino acid. In this way, the proper sequence of amino acids is assembled into a protein.
The vaccine has an mRNA sequence that doesn’t match any human DNA sequence. It therefore encodes a protein that is not normally synthesized by humans, namely the spike protein of the virus. This stimulates the immune response and provides immunity from the virus. It is not possible for someone to be allergic to mRNA. The reactions have been to other ingredients in the vaccine and are similar to those that occur with other vaccines. They are not from mRNA.
Thanks. Good article/info.
Any other 9-month RNA vaccines rushed into mass distro?
But, this is mRNA's first rodeo?
We have comprehensive genomes for just about every kind of cancer.
Where are the mRNA cancer vaccines?
Where are the just-in-time mRNA influenza, common cold, and pneumonia vaccines?
There’s no cancer vaccine because cancer isn’t a virus. It comes from our own cells’ genome running amok and causing the cells to divide uncontrollably. For the other viruses, mRNA might work, but there isn’t a single characteristic protein that we can encode into an mRNA molecule that will stimulate the immune system like the spike protein in the case of the coronavirus that causes COVID.
It’s also not easy to isolate particular sequences in a genome, even a relatively small one like a viral genome, that encode particular proteins. We actually had a head start in this case; work along these lines was done on past related viruses that caused lesser epidemics, SARS and MERS for example. The work wasn’t completed in these cases because those epidemics died off before vaccines could be developed. But those efforts laid the groundwork for the current vaccine.
Obviously.
But, a cancer vaccine can certainly alert the immune system to attack tumors, or attack specific molecules inside tumors.
I wrote my original comment because you stated that mRNA vaccines are safe because we know almost "everything there is to know about mRNA."
If that is true, it seems to me that mRNA cancer vaccines would be common and effective, and clearly they are not.
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