We know pretty much everything there is to know about mRNA. It’s a polynucleotide that occurs in every cell in every living organism, including humans. It functions as a “messenger” (hence the “m”) that transfers genetic information from the DNA in the nucleus to the ribosomes, structures in the cell where protein synthesis occurs. The mRNA consists of a sequence of nucleotide bases that are complementary to the ones in the DNA. Molecules of tRNA pair with the mRNA at the ribosome. Each tRNA is 3 bases long and each binds to a specific amino acid. In this way, the proper sequence of amino acids is assembled into a protein.
The vaccine has an mRNA sequence that doesn’t match any human DNA sequence. It therefore encodes a protein that is not normally synthesized by humans, namely the spike protein of the virus. This stimulates the immune response and provides immunity from the virus. It is not possible for someone to be allergic to mRNA. The reactions have been to other ingredients in the vaccine and are similar to those that occur with other vaccines. They are not from mRNA.
But, this is mRNA's first rodeo?
We have comprehensive genomes for just about every kind of cancer.
Where are the mRNA cancer vaccines?
Where are the just-in-time mRNA influenza, common cold, and pneumonia vaccines?