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A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged
elemental ^ | Sept 1, 2020 | Thomas Smith

Posted on 09/08/2020 1:26:22 PM PDT by metmom

A closer look at the Bradykinin hypothesis

arlier this summer, the Summit supercomputer at Oak Ridge National Lab in Tennessee set about crunching data on more than 40,000 genes from 17,000 genetic samples in an effort to better understand Covid-19. Summit is the second-fastest computer in the world, but the process — which involved analyzing 2.5 billion genetic combinations — still took more than a week.

When Summit was done, researchers analyzed the results. It was, in the words of Dr. Daniel Jacobson, lead researcher and chief scientist for computational systems biology at Oak Ridge, a “eureka moment.” The computer had revealed a new theory about how Covid-19 impacts the body: the bradykinin hypothesis. The hypothesis provides a model that explains many aspects of Covid-19, including some of its most bizarre symptoms. It also suggests 10-plus potential treatments, many of which are already FDA approved. Jacobson’s group published their results in a paper in the journal eLife in early July.

(Excerpt) Read more at elemental.medium.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: bioweapon; bradykinin; bradykininhypothesis; bradykininstorms; coronavirus; covid; covid19; danieljacobson; helixmakemineadouble; oakridge; summit; supercomputer; tennessee
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To: Bobalu

AI is not a myth, but there is no guarantee that the discriminators the AI pattern recognition will decide to use. To AI. in my experience, correlation is equal to causation. To imaginative intelligence, correlation is a clue to potential causation.


61 posted on 09/08/2020 5:14:37 PM PDT by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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To: MHGinTN

Actually, no self-taught computer can beat a chess master. The program that beat the chess master amalgamated the sequence memory of multiple chess experts, including the probabilities of which attack/defense/strategy was being employed - and could even have been informed of which such strategies were most likely employed by the human chess master.

A “computer”, without instructions, is an expensive brick. With the wrong instructions, it is a malicious, expensive brick. With the right instructions, it is a brick of gold.


62 posted on 09/08/2020 5:18:47 PM PDT by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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To: MortMan

Just curious, have you seen the computer program that beat the best GO player? That one learned by gaming AFTER it had been programmed with excellent strategies. It defeated the world’s best GO player in several games. Having played noth games well I consider GO a more challenging game to reach expert. I was on my college Chess Team in the sixties.


63 posted on 09/08/2020 5:28:25 PM PDT by MHGinTN (A dispensation perspective is a powerful tool for discernment)
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To: upchuck

Great advice don’t forget to take Vit A with your vit D they work together


64 posted on 09/08/2020 5:45:48 PM PDT by Steve Van Doorn (*in my best Eric Cartman voice* 'I love you, guys')
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To: MHGinTN

How does a human person perceive the opponent’s strategy in GO? There are likely several methods, all of which would have been incorporated in the program (including programmer-identified shades of gray that the human players wouldn’t have considered).

A properly specified and constructed program is an amalgam of many viewpoints. Most humans can host one, and possibly as many as three, such viewpoints. The simple fact is that computers can memorize centuries of history and determine which path(s) have historically been effective against the pattern they perceive.

What computers cannot do, including AI computers which “learn” based on parameters which are unspecified, and often unknown to their human masters, is come up with a NEW response to an old problem. They can determine which known response reacts well with the identified issue, but they cannot create a new way to see the issue itself.


65 posted on 09/08/2020 5:46:03 PM PDT by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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To: metmom

A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged

They kept seeing m..a..d..e..i..n..c..h..i..n..a in the dna string.


66 posted on 09/08/2020 7:54:18 PM PDT by minnesota_bound (homeless guy. He just has more money....He the master will plant more cotton for the democrat party)
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To: minnesota_bound

LOL!!!


67 posted on 09/08/2020 9:55:26 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith.....)
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To: metmom

The analysis conveniently ignores the preliminary stage of infection when the virus colonizes the lungs.

I find this omission both disturbing and expected.


68 posted on 09/08/2020 10:18:08 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: logi_cal869

How would that change things?


69 posted on 09/09/2020 5:47:32 AM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith.....)
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To: metmom

“How would that change things?”


Hmmm...lessee:

Would you wait until you see flames shooting out your windows to call the fire department to put out your house on fire, or act when you see the first signs of smoke?

The analogy is very apt in this regard.


70 posted on 09/09/2020 5:53:18 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: metmom

Plus that approach worked for me.


71 posted on 09/09/2020 5:53:58 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: logi_cal869

The article didn’t seem to be so much about treatment options as much as how the virus works.

The kind of reaction it causes and why it expresses in such weird ways.

At first, everyone was focused on the cytokine storm and it seem to be that it’s a different kind of reaction. They didn’t expect that.


72 posted on 09/09/2020 6:07:34 AM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith.....)
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To: metmom

Uh-huh. If there’s any medical validity to this at all (and not a political move to support mask mandates) then this reinforces my working theory that the viral load is delivered via the respiratory tract.

https://www.foxnews.com/health/coronavirus-infection-severity-face-mask-use-study

Mask ‘science’ aside: Put out a small fire early, or risk burning down the house.

The computer model has one major flaw: It was programmed by a human with bias.


73 posted on 09/09/2020 7:26:35 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: logi_cal869

That’s the first *study suggests* article that I have seen that actually builds a case for mask wearing that makes sense.


74 posted on 09/09/2020 11:13:00 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith.....)
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To: metmom

Except it fails 100% to explain why 6000 college students have tested positive with zero hospitalizations, that there’s a greater risk of drowning for most of the population and that the MEDIAN age of deaths this week is...

...NINETY FOUR (94).

Masks have no business being mandated upon the healthy for viral infections. That’s a scientific fact proven by death rate parity between U.S. & Sweden, achieved last week.


75 posted on 09/10/2020 7:09:05 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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