Corona Virus Daily Thread #50 COVID-19 5/04/2020

many | 5/4/2020 | many

[RaceBannon]

Corona Virus Daily Thread #50 COVID-19 5/04/2020

[DEPcom]

"Provisional Death Counts for Coronavirus Disease (COVID-19):"

I saw social media posting claiming this all over the place. I can see why people are confused.

Someone is taking data out of context. Hopefully this helps some people understand the difference in numbers.

Provisional define: existing for the present, possibly to be changed later. Meaning those numbers are not the final numbers. The numbers are waiting on some actions to be completed. More Death Certificate on the way.

The Provisional Death is always two weeks behind the higher numbers.

NCHS quote on the lower : "“Our counts often track 1–2 weeks behind other data for a number of reasons: Death certificates take time to be completed. There are many steps involved in completing and submitting a death certificate. Waiting for test results can create additional delays. States report at different rates."

Here is a good report explaining the different in numbers.

[RummyChick]

Increased von Willebrand factor levels in patients with systemic lupus erythematosus reflect inflammation rather than increased propensity for platelet activation

....
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013501/

Hydroxychloroquine treatment is common place in SLE, as it reduces relapse rates and the risk of thrombotic events,31 and in experimental lupus models, the drug has been found to reduce endothelial dysfunction.14 42 We did not find a significant effect of sustained hydroxychloroquine therapy on of VWF levels or platelet aggregation activity in our cohort, suggesting that hydroxychloroquine exerts its vasoprotective effects through other pathways. Similarly, we were unable to detect an effect of antiphosphol

[Fury]

Apparently, their clothing is magical since the virus lives on most things for 3+ days.

You're getting called out for that ("the virus lives on most things for 3+ days").

"Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1"
- see https://www.nejm.org/doi/full/10.1056/NEJMc2004973

“Stability of SARS-CoV-2 in different environmental conditions”
-see https://www.sciencedirect.com/science/article/pii/S2666524720300033?via%3Dihub

In the last study, they tested using cloth. There was no virus titer detected after two days and in two time periods less than two days, only one of the triplicate reactions was positive in the TCID50 assays, suggesting it may be less than two days for the virus titer to be detectable. These were in highly controlled laboratory conditions.

[mrsmith]

https://twitter.com/DrCSWilliam/status/1258154815080857605
Anti-opening.

Now I’d like to know how many they tested to get 99 new cases.

[RummyChick]

George Tzoras
7 hours ago
Medcram what about if the destruction of endothelial cells leads to exposure of the subendothelial collagen and tissue factor? So coagulation occurs due to both increased vWF and exposure of SEC.

[mrsmith]

Found it: they had to test 1652.
For a rate of 5.7%.
Which is pretty good.
Though they do seem to be at a plateau instead of a falling rate. So... IDK.,

[RummyChick]

typo O blood deals better with the Von Willebrand factor as per medcram

[RummyChick]

I actually may have some kind of issue with this von willabrand thing so went to see what kind of tests I could order once I go back into the world

they are pretty expensive at direct labs

https://www.directlabs.com/OrderTests/tabid/55/language/en-US/Default.aspx

if I end up the the ER I am going to ask for them since I have a history of long nose bleeds for no reason when I was younger until my mother had them do something to me...and blood sometimes that takes longer to clot

i still remember having to put cold scissors on back of neck because she thought it would help. i think it did

[PA Engineer]

Couldn't find the link to where you said you worked for Battelle.

Battelle Cleared to Sterilize N95 Masks at Max Capacity

I think I know why.

At first I thought there were to many links and points of failure to this process and then I thought of another possibility.

With their established research background, is this a proxy method to monitor both viral distribution and mutation from medical facilities throughout the US? Your thoughts?

[steve86]

I worked at https://www.pnnl.gov

[RummyChick]

btw, medcram mentions AdamTS13 in his thrombosis talk of Covid19...and mentions the word ZINC containing enzyme.

[blueplum]

thnks for that summary, Fury. I was falling asleep and appreciate your breaking out the points. Good news on the statins - cardiac patients have one brownie point working to their advantage, at least. :)

[mrsmith]

https://www.golemanalyticsproject.com/Covidmap/

County level map. Shows cases and percentages.
Not sure it’s complete yet.
But interesting.

[riri]

That is what most of us have surmised from the beginning.

[blueplum]

thanks much, Race. I watched both and think I need to watch it again - lots of names named. I was a little confused on the second video where she said something about a 2017-18 ‘military’ memo that referenced higher succeptibility covid-19 from the H1N1 flu vaccine? But ccpvirus wasn’t around in 2017. She did seem more focused on the HIV background. Cant say I find her completely believable but enough so that it’s worth sniffing around the rabbit hole.

She did bring up a point about ‘royalties’ of patents. Should royalties on (whatever) R&D inventions/breakthroughs developed as a direct result of govt funded education/research grants/facilities - especially those that utilize undergrads/military assets as free labor - be going to any one individual? Why aren’t they a public royalty, that goes to a dedicated govt fund, used only to augment the funding of even more R&D?

[justa-hairyape]

Omg. Various sources ? I must change my thinking.....not.

[blueplum]

just to jump in here on the canvassing topic, my only concern would be the cost. $40 to the agency per hour, $20-25 to the ‘private investigator’ (paralegals?) is a lot of lettuce. What happened to telemarketers? We’d save at least half. :)

[justa-hairyape]

A recent large group of autopsies in Germany showed only a small percentage even developed pneumonia. It is not ARDS.

[mrsmith]

https://twitter.com/joshrogin/status/1258126913287184384

“The line censored in the EU oped was that the outbreak of coronavirus was “in China” and “subsequently spread to the rest of the world.” That’s what the Chinese government demanded they erase... and they obliged. Awful.”

[justa-hairyape]

Think the problem is that this is a brand new disease in humans. We have no idea what long term affects will be or what short term mutations will bring. At any rate, the Flu Bro Titanic sinks again.