Posted on 04/19/2020 6:28:07 AM PDT by SeekAndFind
Dozens of people taking hydroxychloroquine and other autoimmune drugs for chronic ailments such as lupus and rheumatoid arthritis have tested positive for the CCP (The Chinese Communist Party) virus, according to data compiled by the Global Rheumatology Alliance.
The study is sponsored by an international collaborative, the COVID-19 Global Rheumatology Alliance, which includes a large group of academics, clinicians, and patients working together, and so far suggests that hydroxychloroquine doesn’t always protect against the disease, which originated in Wuhan, China, in December last year.
Over 9,500 patients have submitted surveys to the alliance, of which nearly half were diagnosed with rheumatoid arthritis or lupus. Nearly a third of all respondents with the chronic disease said they were taking hydroxychloroquine, of which 189 (7 percent) said they were diagnosed with the virus.
Separately, patient information provided by rheumatologists and published on Thursday in The Lancet Rheumatology also suggests the antimalarials may not adequately protect people from the virus. Of the first 110 patients reported, 69 were taking medications such as hydroxychloroquine to treat chronic ailments like systemic lupus erythematosus and rheumatoid arthritis, before being diagnosed with the coronavirus.
As of April 1, 2020, 110 individuals with rheumatic disease who have been diagnosed with COVID-19 are included from six continents: Europe, North America, South America, Asia, Africa, and Oceania.
However, the research doesn’t specifically address whether hydroxychloroquine is effective at treating coronavirus symptoms, and researchers acknowledged that one limitation to the study is that some countries test only people showing severe symptoms.
Jinoos Yazdany, chief of the division of rheumatology at Zuckerberg San Francisco General Hospital, told The Wall Street Journal that the antimalarial doesn’t fully protect people from contracting the new virus and is “not a magic bullet because people that are on it are contracting the infection.”
On March 28, the Food and Drug Administration (FDA) authorized emergency use of the drug, which President Donald Trump has also touted as a “game changer” in the fight against the CCP virus, allowing the federal government to begin distributing millions of doses to states across the United States. However, as of yet, no large clinical trials have been conducted to validate smaller studies and prove the drug can safely be used to treat the disease, prompting medical professionals, including Dr. Anthony Fauci, the United States’ leading infectious disease expert and a member of the White House coronavirus task force, to caution against using the drug.
Speaking at a White House news conference on March 20, Fauci said data on the drug so far “was not done in a controlled clinical trial. So you really can’t make any definitive statement about it,” and that only such studies would determine if the drug was truly safe and effective.
A number of clinical trials exploring the drug’s efficacy and safety are currently underway around the world, including a 1,500-person trial at the University of Minnesota. Three early studies, two from France and one from China, indicate a benefit of utilising hydroxychloroquine but have been branded inadequate by some in the medical community.
India, which manufactures 70 percent of the world’s supply of hydroxychloroquine, agreed on April 7 to lift an earlier ban on the export of the drug following a telephone conversation between U.S. President Donald Trump and Indian Prime Minister Narendra Modi. Trump had said at a previous press conference that India could face retaliation if it failed to lift the ban and release the 29 million doses of the drug it had ordered for its medical stockpile.
RE: Put it into perspective. HCQ is malaria pills. If you were posted to a foreign assigment where malaria was a problem, you’d take it daily like a vitamin. Zinc IS a vitamin.
And back to the question -— how many percent of those who take HCQ against Malaria still get Malaria nonetheless? Or is it 100% protective?
The answer to the above question is important because the study in this article tells us that only 7% of those who take HCQ were infected with Covid-19, meaning 93% of the others were not.
Now if Malaria is similarly 93% protective, then I would say that this study implies that HCQ is just as good for Covid-19 as it is for Malaria. But I don;t really know the Malaria figure.
RE: Was it taken with Zithromax? If not, then the Trump pills aren’t as effective.
OK, do you know a protocol for NON-INFECTED people to protect against Covid-19?
1) What dosage of HCQ and Zinc must one take?
2) How FREQUENT must one take that combo? Daily? If so how often and how long?
Is the goal to prevent exposure/infection, or to prevent illness? Exposure doesn’t mean illness - that takes replication by the virus unless the initial infection is a massive viral load. A normal infection starts with a moderate or low load, then progresses to illness via replication.
The flu shot, when it works, decreases the level of illness by having antibodies already in the body that can fight off the infecting virus from day 1. With a new virus like CCP Wuhan, nobody has effective antibodies. The vaccine Fauci and company speak of will work the same way.
It is not about preventing infection by a virus. It is about preventing illness.
RE: Is the goal to prevent exposure/infection, or to prevent illness?
Seeing how Doctors and Healthcare workers are using HCQ for themselves, I would say their primary goal is to prevent infection.
Why? Because one can be infected and still be asymptomatic and that is DANGEROUS in a hospital setting with so many vulnerable people.
So, if it does not prevent infection, taking it is pretty useless and I would suggest saving it for AFTER you are infected.
There may be some truth in this article.
But these drugs may be the best therapy we have at the moment.
If you are infected and do not want to take this therapy, that is your choice.
And you can die on a ventilator if you wish too.
Vegans are at risk more so than omnivores. The meat eaters are at a disadvantage if they avoid shellfish, especially oysters.
https://journals.sagepub.com/doi/pdf/10.1177/156482650102200204
Well you can disagree all you want, but the fact is that lupus patients have immunity issues, so it is important. Also how quickly they recover, if they do, is also important.
I’m screwed. I actively avoid oysters.
As a prophylaxis we assume that zinc is normal in the healthy Patient. As a treatment it is the combination of HCQ and azithromycin thst is effective. Even in my most critical of patients it is turning them around impressively.
Stop with the zinc. While not likely does not hurt the evidence that is it requires is scant. It is at best 2B recommendation ... not harmful possibly helpful.
RE: Well you can disagree all you want, but the fact is that lupus patients have immunity issues, so it is important. Also how quickly they recover, if they do, is also important.
Sigh, there you go using the word “recover”. I am lready convinced that HCQ plus Zithromax plus Zinc Combo quickly aids in recovery AFTER one is infected with Covid-19, but that isn’t what I am interested in this thread.
I am interested in HCQ being a PROTECTOR against infection. Please don’t use the word “recover” in this thread <— we never disagreed on this one.
Prophylaxis utilizing plaquenil:
1. 800 mg day #1 loading dose given in divided doses 12 hours apart (400 mg twiddle on day 1)
2. 400 mg every seventh day after the loading dose for seven weeks
No zinc recommended
Prophylaxis provided for 12 week using this formula
HCQ has a half life of 46 days
You are describing the behavior of a preparation in a dish where you CAN alter the concentration of Zinc. In the interstitial space you can’t. The article I linked above is the most comprehensive article I have ever seen on “Zinc Metabolism”.
Look at it this way, something more people are familiar with. Sodium metabolism. “How much table salt would you have to ingest to raise your interstitial Sodium level (Na+) from 140 mole per deciliter to 141?” The answer is you pretty much can’t do it. You will just put a lot more Na in your urine.
Deficiency states for NA work pretty much the same for Zinc, you have two pools of “reserves” from which to mobilize, a “Readily mobilizable pool” and a “Not Readily mobilizable pool” that is much larger because it is BONE.
IOW you will repair a deficiency of Na or Zn much faster from these pools than your diet. Or Supplement.
I couldn’t disagree more with your take on this.
There is ZERO disappointment and ZERO significance to realizing a drug won’t actually prevent infection from a virus. What drug has ever done this for a virus?
This was never hoped or claimed for.
Someone touting this as a headline or some significant discovery is a bad joke.
It is such a ridiculous bar to set, I have to wonder if the study/article were paid for by the vaccine industry.
They pointedly avoided even looking at what the drug was hoped to do, and believed to do, reduce the severity of disease upon infection.
If a huge percent of people who take low dose HCQ once a week end up with asymptomatic infections instead of worse categories of severity, that is a huge benefit and not a disappointment in any way.
Yes people who are asymptomatic can still infect others, although they are much less infectious than worse cases (viral load). If it saves lots of lives among high risk individuals, that is the farthest thing possible from being a disappointment.
News is coming out now that the numbers of asymptomatic infections for C19 are far bigger than previously thought.
By the way if you are stationed in a place with risk of malaria they give you low dose once a week for prophylactic, not daily.
Same for c19, low dose once a week for prophylactic, high dose daily for acute/severe treatment (under close supervision with zinc/zpak)
Geez, is it stupidity of disinformation or both that keeps being peddled to the public. HCQ is not just an anti-inflammatory to treat arthritis. Its biggest claim to fame in treating the virus is that it is an ionophore. I’m not a doctor and even I can understand how it works. It has to be administered in companion with a therapeutic - zinc in the case of COVID-19.
That’s the point. I was replying to your post that you be newer drugs list death as a side effect
RE: IOW you will repair a deficiency of Na or Zn much faster from these pools than your diet. Or Supplement.
So, bottom line — Supplements of ANY kind are pretty useless?
I stopped reading this worthless piece after scanning and seeing this halfway down:
“However, the research doesn’t specifically address whether hydroxychloroquine is effective at treating coronavirus symptoms”
RE: There is ZERO disappointment and ZERO significance to realizing a drug won’t actually prevent infection from a virus. What drug has ever done this for a virus?
This was never hoped or claimed for.
Well, then we better tell many Doctors and healthcare workers who are taking HCQ now as preventative to STOP as they are simply wasting their money and making the drug more scarce for patients who really need it.
Hcq role will probably be that of an agent which moderates the bodies immune response so that vital tissue is not overwhelmed by immune system. Pt can then recover with antibiotics...mechanical assistance...fluids etc without deleterious effects of immune system.
To stop virus from reproducing a compund which inhibits its replication would eradicate it. Same tact used with many virus related disease.
Well that’s all well and good but I am glad you say you aren’t a doctor for you are peddling the misinformation. Zinc is not a therapeutic. St best is an adjunct. The reason HCQ snd azithromycin is used has been extensively documented as a mechanism for the critically ill in minor round of my other posts.
Please, for the love of God, stop perseverating on the zinc.
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