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Hydroxychloroquine, Other Autoimmune Drugs Don’t Fully Protect Against COVID-19, Research Sponsored by Global Rheumatology Alliance Suggests
Epoch Times ^ | 04/9/2020 | BY KATABELLA ROBERTS

Posted on 04/19/2020 6:28:07 AM PDT by SeekAndFind

Dozens of people taking hydroxychloroquine and other autoimmune drugs for chronic ailments such as lupus and rheumatoid arthritis have tested positive for the CCP (The Chinese Communist Party) virus, according to data compiled by the Global Rheumatology Alliance.

The study is sponsored by an international collaborative, the COVID-19 Global Rheumatology Alliance, which includes a large group of academics, clinicians, and patients working together, and so far suggests that hydroxychloroquine doesn’t always protect against the disease, which originated in Wuhan, China, in December last year.

Over 9,500 patients have submitted surveys to the alliance, of which nearly half were diagnosed with rheumatoid arthritis or lupus. Nearly a third of all respondents with the chronic disease said they were taking hydroxychloroquine, of which 189 (7 percent) said they were diagnosed with the virus.

Separately, patient information provided by rheumatologists and published on Thursday in The Lancet Rheumatology also suggests the antimalarials may not adequately protect people from the virus. Of the first 110 patients reported, 69 were taking medications such as hydroxychloroquine to treat chronic ailments like systemic lupus erythematosus and rheumatoid arthritis, before being diagnosed with the coronavirus.

As of April 1, 2020, 110 individuals with rheumatic disease who have been diagnosed with COVID-19 are included from six continents: Europe, North America, South America, Asia, Africa, and Oceania.

However, the research doesn’t specifically address whether hydroxychloroquine is effective at treating coronavirus symptoms, and researchers acknowledged that one limitation to the study is that some countries test only people showing severe symptoms.

Jinoos Yazdany, chief of the division of rheumatology at Zuckerberg San Francisco General Hospital, told The Wall Street Journal that the antimalarial doesn’t fully protect people from contracting the new virus and is “not a magic bullet because people that are on it are contracting the infection.”

On March 28, the Food and Drug Administration (FDA) authorized emergency use of the drug, which President Donald Trump has also touted as a “game changer” in the fight against the CCP virus, allowing the federal government to begin distributing millions of doses to states across the United States. However, as of yet, no large clinical trials have been conducted to validate smaller studies and prove the drug can safely be used to treat the disease, prompting medical professionals, including Dr. Anthony Fauci, the United States’ leading infectious disease expert and a member of the White House coronavirus task force, to caution against using the drug.

Speaking at a White House news conference on March 20, Fauci said data on the drug so far “was not done in a controlled clinical trial. So you really can’t make any definitive statement about it,” and that only such studies would determine if the drug was truly safe and effective.

A number of clinical trials exploring the drug’s efficacy and safety are currently underway around the world, including a 1,500-person trial at the University of Minnesota. Three early studies, two from France and one from China, indicate a benefit of utilising hydroxychloroquine but have been branded inadequate by some in the medical community.

India, which manufactures 70 percent of the world’s supply of hydroxychloroquine, agreed on April 7 to lift an earlier ban on the export of the drug following a telephone conversation between U.S. President Donald Trump and Indian Prime Minister Narendra Modi. Trump had said at a previous press conference that India could face retaliation if it failed to lift the ban and release the 29 million doses of the drug it had ordered for its medical stockpile.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid19; hcq; hydroxychloroquine; prophylaxis
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To: SeekAndFind

I am saying that the tone of the article appears to be aimed at tearing down thoughts of HCQ as a prophylaxis because it is not 100% effective. That standard is applied nowhere else in medical science.


21 posted on 04/19/2020 6:53:08 AM PDT by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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To: Chauncey Gardiner

https://academic.oup.com/jn/article/130/5/1360S/4686372


22 posted on 04/19/2020 6:53:13 AM PDT by wastoute (Government cannot redistribute wealth. Government can only redistribute poverty.)
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To: Mom MD

Death is a side effect of many drugs. Look at the black box labels. HCQ like any drug has side effects, but also has a decades long track record of relatively safe use for malaria, lupus, and rheumatoid arthritis. Most physicians should be aware of contraindications which would preclude its use with individual patients. All drugs have side effects - even aspirin.


23 posted on 04/19/2020 6:54:37 AM PDT by TheConservativeBanker
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To: MortMan

RE: If it is only how many were diagnosed, then the flu shot should be banned, as it is considered only (at best) 40% effective.

That’s a very fair observation. That would imply that:

* A Covid-19 vaccine could possibly ( God forbid ) not be fully effective like the flu vaccine.

* The other question is this -— How fully protective is HCQ against Malaria for which it has been used for 60 years? If it is 93%, then heck, this study simply replicates what HCQ does for Malaria, but that’s a big IF. I don’t know the percentage of protectivity it has against Malaria.


24 posted on 04/19/2020 6:55:29 AM PDT by SeekAndFind (look at Michigan, it will)
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To: RonnG

Not a word about zinc. Not one.

HCQ alone isn’t what works. The two in tandem work. It’s the zinc that provides the protection. HCQ opens the channel.


25 posted on 04/19/2020 6:56:03 AM PDT by RinaseaofDs
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To: MortMan

RE: I am saying that the tone of the article appears to be aimed at tearing down thoughts of HCQ as a prophylaxis because it is not 100% effective. That standard is applied nowhere else in medical science.

Then question to ask is this -— How fully protective is HCQ against Malaria for which it has been used for 60 years? If it is 93%, then heck, this study simply replicates what HCQ does for Malaria, but that’s a big IF. I don’t know the percentage of protectivity it has against Malaria.


26 posted on 04/19/2020 6:56:30 AM PDT by SeekAndFind (look at Michigan, it will)
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To: RinaseaofDs; RonnG

RE: HCQ alone isn’t what works. The two in tandem work. It’s the zinc that provides the protection. HCQ opens the channel.

Are you referring to Zinc plus HCQ as TREATMENT for Covid-19 patients? We know that Zinc is an important component for TREATMENT.

Or are you saying that to be an effective protective against Covid-19 infection, one must ALSO take Zinc together with HCQ?

People in this thread don’t bother to read the article. It is not talking about treatment but PROTECTION AGAINST INFECTION.


27 posted on 04/19/2020 6:57:51 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

I don’t know

And Larry elder and others have been looking for data on people with Lupus and CV19...

also this doesn’t mention antibodies (previous exposure)


28 posted on 04/19/2020 6:57:52 AM PDT by a fool in paradise (The fish wrap media promoted Obama's Benghazi lies in 2012.)
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To: SeekAndFind

We agree on the points you made in that post, but I still contend a diagnosis without serious symptoms should not count against the effectiveness.

I also wonder about whether they accounted for zinc intake in the study.


29 posted on 04/19/2020 6:58:48 AM PDT by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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To: SeekAndFind

Not treatment. Prophylaxis. HCQ and zinc together. IF you are infected, add a antibiotic that isn’t going to impact you from a cardiac sense.

HCQ and zinc together. One opens the zinc channel, and the other is what goes into the cell.


30 posted on 04/19/2020 7:01:33 AM PDT by RinaseaofDs
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To: MortMan

RE: I also wonder about whether they accounted for zinc intake in the study.

Are you saying that to be an effective protective against Covid-19 infection for those not infected, one must ALSO take Zinc together with HCQ the same way patients do during treatment?


31 posted on 04/19/2020 7:02:41 AM PDT by SeekAndFind (look at Michigan, it will)
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To: RinaseaofDs

RE: Not treatment. Prophylaxis. HCQ and zinc together.

OK, do you know a protocol for NON-INFECTED people to protect against Covid-19?

1) What dosage of HCQ and Zinc must one take?

2) How FREQUENT must one take that combo? Daily? If so how often and how long?


32 posted on 04/19/2020 7:04:17 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

To my layman’s understanding, HCQ works with zinc to prevent virus replication. It is not a shield against exposure and infection, but rather against significant progression of the infection and disease.

If the CCP virus can be rendered into the same category as the flu with respect to hospitalizations and deaths, then the virus is no longer a cause for panic.


33 posted on 04/19/2020 7:07:13 AM PDT by MortMan (Shouldn't "palindrome" read the same forward and backward?)
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To: SeekAndFind

The real question is not if it prevents them from getting Covid-19, but rather if they feel any ill effects of Covid-19, and do they recover?


34 posted on 04/19/2020 7:09:01 AM PDT by Robert DeLong
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To: MortMan

RE: To my layman’s understanding, HCQ works with zinc to prevent virus replication. It is not a shield against exposure and infection, but rather against significant progression of the infection and disease.

Well thanks for that. If what you said is true, This seems to make the seeming mass usage of doctors and nurses of HCQ to protect themselves against infection useless then.

You only take it AFTER you get infected. Taking it BEFORE you get infected to protect yourself is pretty much useless.

Millions of Indians who are using HCQ as protective are simply wasting their money.


35 posted on 04/19/2020 7:10:35 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

My daughter is in the HC industry. She’s not on such a protocol but other HCPs ARE on a protocol to prevent the manifestation of symptopms.

I’ll ask what they are doing. We have a firefighter running our Troop now. He mentioned some first responders are on it too.

So, if you get it, it doesn’t flare. You may get still get it.

Put it into perspective. HCQ is malaria pills. If you were posted to a foreign assigment where malaria was a problem, you’d take it daily like a vitamin. Zinc IS a vitamin.


36 posted on 04/19/2020 7:11:46 AM PDT by RinaseaofDs
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To: Robert DeLong

RE: The real question is not if it prevents them from getting Covid-19, but rather if they feel any ill effects of Covid-19, and do they recover?

I have to disagree with you. Not feeling the effects does not mean you are not a carrier. In fact, it has been argued that MOST of those who are infected are asymptomatic but INFECT other vulnerable people nonetheless.

PREVENTION (as in having a sort of vaccine effect ) is IMPORTANT. If you don’t get it, you don’t infect the vulnerable.


37 posted on 04/19/2020 7:12:37 AM PDT by SeekAndFind (look at Michigan, it will)
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To: RinaseaofDs

RE: She’s not on such a protocol but other HCPs ARE on a protocol to prevent the manifestation of symptopms.

Yes, but just because you don’t display symptoms does not mean you are NOT infected. In fact, being infected and not symptomatic is DANGEROUS, especially for healthcare workers. They could still be feeling good, but they could INFECT the vulnerable around them.


38 posted on 04/19/2020 7:14:30 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

It is not the Hydroxychlorquine that stops the virus, it’s the zinc. The Hydroxychlorquine makes a hole in the cell wall that enables the zinc to get in and stop the virus from replicating.

Yes, I am saying the two must go together.

The antibiotic (z-pack or similar) would only be needed in people who have had the virus long enough for an infection to develop in CCP virus patients.


39 posted on 04/19/2020 7:14:47 AM PDT by jacknhoo (Luke 12:51; Think ye, that I am come to give peace on earth? I tell you, no; but separation.)
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To: SeekAndFind

Was it taken with Zithromax? If not, then the Trump pills aren’t as effective.


40 posted on 04/19/2020 7:15:32 AM PDT by MuttTheHoople
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