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Hydroxychloroquine & Metformin
American Association for the Advancement of Science (Science Translational Medicine/In The Pipeline) ^ | 6 April 2020 | Derek Lowe

Posted on 04/07/2020 4:55:52 AM PDT by Sarcasm Factory

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Disappointing but perhaps unsurprising. Virtually all clinically significant pharmaceuticals have their inherent risks and dangerous interactions. -_-
1 posted on 04/07/2020 4:55:52 AM PDT by Sarcasm Factory
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To: Sarcasm Factory

I figure if it could save everyone, we wouldn’t be having all these deaths. But it has seemed to help some.


2 posted on 04/07/2020 4:59:55 AM PDT by Williams (Stop Tolerating The Intolerant)
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To: Sarcasm Factory

I think it will be proven eventually it is the Zinc given with the hydroxychloroquine that kills the viral cells.


3 posted on 04/07/2020 5:04:33 AM PDT by free_life (If you ask Jesus to forgive you and to save you, He will.)
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To: Sarcasm Factory

I agree, if it showed any promise in clinical use it would be ‘the’ goto treatment, but it’s not. I would want to try it if I became positive simply because of the low risk of the side effects.


4 posted on 04/07/2020 5:05:27 AM PDT by devane617 (Kyrie Eleison, where I'm going, will you follow?)
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To: free_life

DITTO...Zinc


5 posted on 04/07/2020 5:05:50 AM PDT by devane617 (Kyrie Eleison, where I'm going, will you follow?)
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To: Sarcasm Factory; Williams

Where is the Zinc? AZ has minor antiviral effects, but only minor. It is there merely to prevent opportunistic infections. The HQ does nothing but open a pathway into the cell for zinc and has some minor anti-inflammatory effects. Zinc interferes with the reverse transcriptase enzyme the virus uses to duplicate itself. No Zinc, no real benefit. Zinc does not like to go into cells. HQ lets it go in easily.


6 posted on 04/07/2020 5:06:04 AM PDT by LesbianThespianGymnasticMidget (Our parents/grandparents were called to war. We have been called to sit on the couch. We got this!!)
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To: Sarcasm Factory
The author is being selective in his citations.

Hydroxychloroquine is routinely given to travelers who visit 3rd world countries and no one screams about "potential" hazards when its given out.

Lackey for big pharma.

7 posted on 04/07/2020 5:13:36 AM PDT by KC_Conspirator
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To: LesbianThespianGymnasticMidget

True that!

I wonder if in a pinch that Tonic Water and Zinc may be enough to bring patients back to health. ??


8 posted on 04/07/2020 5:14:45 AM PDT by free_life (If you ask Jesus to forgive you and to save you, He will.)
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To: free_life

Yep! Zinc, Zinc, Zinc. When a lot of these people talk about HCQ, they only mention taking it with the Z-Pac. They never mention the main ingredient Zinc. Are they including it in the cocktail?


9 posted on 04/07/2020 5:16:13 AM PDT by deweyfrank (Nobody's Perfect)
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To: KC_Conspirator

BINGO!

Boris Johnson who banned its use in the U.K. very well may have taken this drug if he ever travelled to Africa.

I wonder if now he’s reconsidering?


10 posted on 04/07/2020 5:16:20 AM PDT by David Chase
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To: Sarcasm Factory

And yet four entries above this one is an article in Nature claiming something pretty different.

In other words, we just do not know, but the media will insist that we do ONLY those things which those well-eddikated journalists tell us we should do.


11 posted on 04/07/2020 5:19:18 AM PDT by Da Coyote
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To: Sarcasm Factory

Uh-oh.

Wonder about the others. Remdesivir, etc.


12 posted on 04/07/2020 5:19:48 AM PDT by sauropod (Pelosi Galore: We know she's lying when we see her dentures flying.)
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To: Sarcasm Factory

This seems like a very small, very flawed study, in which very sick people were given less than the recommended regimen, and then failed to miraculously get better.

Is this how they do science?


13 posted on 04/07/2020 5:22:29 AM PDT by ClearCase_guy (If White Privilege is real, why did Elizabeth Warren lie about being an Indian?)
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To: free_life
I've been writing medcram for that. Yes, tonic water will act as a zinc ionosphore (sp) but, unfortunately, you would have to drink 4L of the stuff since it, by law, only has 63 mg of quinine. Your blood sugar would kill you before the coronavirus did :)

However, one gin and tonic a day can't hurt...I'm using plymouth navy strength gin + fevertree elderberry tonic water (or tonic water light).

I also have quercetin but not taking that yet.

14 posted on 04/07/2020 5:22:34 AM PDT by DCBryan1 (Quit calling them liberals, progs, socialists, or democrats. Call them what they are: COMMUNISTS!!!!)
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To: Sarcasm Factory

Many studies confirm a decline of zinc levels with age. Most of these studies do not classify the majority of elderly as zinc deficient, but even marginal zinc deprivation can affect immune function.


15 posted on 04/07/2020 5:26:07 AM PDT by tired&retired (Blessings)
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To: free_life

Yes, the drug opens the door for zinc to kill the virus.

Using the drugs in elderly without zinc supplements is like using a gun with no bullets.


16 posted on 04/07/2020 5:29:14 AM PDT by tired&retired (Blessings)
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To: Sarcasm Factory

I consider metformin to be poison and will not take it, at all, for any reason - even against my doctor’s advice.


17 posted on 04/07/2020 5:29:17 AM PDT by taxcontrol (stupid should hurt (Dad's wisdom))
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To: Sarcasm Factory

Did the author intend to portray the medicine as a poison?


18 posted on 04/07/2020 5:30:44 AM PDT by granada
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To: Sarcasm Factory

Wow, hubby takes Metformin.

Thanks for posting.


19 posted on 04/07/2020 5:30:56 AM PDT by grame (May you know more of the love of God Almighty this day!)
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To: tired&retired

A protective role of zinc in cancer has been indicated by some studies. In vitro, zinc has demonstrated efficacy in inducing apoptosis in glioma (3), bladder (4), prostate (5), as well as breast cancer (6) cells.

http://ar.iiarjournals.org/content/35/10/5309.full.pdf


20 posted on 04/07/2020 5:31:10 AM PDT by tired&retired (Blessings)
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