Coronavirus Live Update Jan 27, 2020 (Agenda-Free TV)

Agenda Free TV ^ | Jan 27, 2020

[11th_VA]

Steve’s the man !!!

China’s Statistics for this morning are late - May be release 8 PM EST

[LilFarmer]

“Two people from Japan and Germany who had contracted coronavirus had not visited the area in China where the deadly viral outbreak originated, authorities have confirmed. One of the patients was a Japanese tour bus driver in his 60s in the city of Nara who had driven two groups of Chinese tourists who had come from Wuhan earlier this month.​“ https://www.independent.co.uk/news/world/asia/coronavirus-china-japan-latest-outbreak-bus-driver-wuhan-death-toll-a9305406.html

[Black Agnes]

Sounds like WE might suspect it’s ...hinky...

I want to know HOW, out of all the respiratory illnesses in any major city in the winter...they detected the ‘signal’ of this PARTICULAR virus, in DECEMBER, when it was many fewer than 100 sick with this, out of the ‘noise’ of the thousands of OTHER cases of URI and pneumonia...

[boxlunch]

If so, why no warning to us?

[bert]

The report I read yesterday said that those who died, also had pneumonia.

The two pneumonia shots might be prudent.

[Myrddin]

I have friends who just retired to PI new Altavas City. They built a very nice home there. His wife comes from the area, so lots of family support.

Paired with that good report, is that warm, humid climates are ideal for Coronavirus. Earthquakes, volcanoes and hurricanes are part of the package deal.

Even with all of their inside knowledge and contacts, it has taken 8 months for all of their personal effects to be shipped to their island after being held in PI customs. Ordering stuff on Amazon gets you service in WEEKS. It's not USA level service. You'll have to adapt to different levels of service.

[Myrddin]

CDC live presser says they have a sequence from Japan for the spike protein. They hope to employ that as an "immunogen" as a starting point for a vaccine. Optimistic estimates are 3 months to a Phase 1 trial, 6 months to a Phase 2. After significant Phase 2 analysis, the earliest vaccine that might be employed for humans would become a possibility.

IMHO, this virus is moving so fast, the vaccines will come far too late to stave off a pandemic with large casualties.

[janetjanet998]

“Risk to general population low but risk for people with contact with those infected higher”

and this is why we pay these people huge bucks for...to come up with these “smart” things

[janetjanet998]

IMHO, this virus is moving so fast, the vaccines will come far too late to stave off a pandemic with large casualties.

---

why would anyone drug company want to take a risk to develop any drugs these days...10 years from now they might get sued for 100 Billion dollars because someone developed a rash as a side effect

[Black Agnes]

That might work if the spike protein is a highly conserved region between subsequent transmissions over the next 3 or 4 months.

We’ll see.

[Black Agnes]

Vaccines are immune from lawsuits. If you have an issue you have to go to a federally moderated vaccine court. Any payouts you get come from a coffer of monies derived from a $0.75/antigen from vaccines given.

Pretty sure ‘emergency’ vaccinations don’t even get litigated in vaccine court. I seem to remember legislation passed as a result of 9/11 for this one. I could be wrong on this aspect.

[Myrddin]

The US government has essentially immunized the vaccine industry from financial consequences. If you're injured by a vaccine, you have to go to "Vaccine Court" to plead your case.

[Paul R.]

Thanks for that link. The vid is a bit reassuring, esp. in that the procedures are not something hastily whomped up.

[thesearethetimes...]

I am way behind on this, but my gosh - how can they talk about full transparency when they still - so far as I have been able to find - will not disclose which are the 26 states under watch?

[Black Agnes]

Because we might ‘panic’.

That would be worse than anything else.

Heaven forbid people have knowledge to make reasonable decisions on their own w/o some govt apparatchik micromanaging the situation.

[Black Agnes]

https://www.hindawi.com/journals/av/2011/734690/

https://www.ncbi.nlm.nih.gov/pubmed/27805261

[grey_whiskers]

You're reaching the limits of my knowledge of immunology here; I understand designing a vaccine which will recognize the spike protein on the surface; but is the protein recognized by the antibodies necessarily the same as the active site to which antibodies adhere to the invading virus? (Thinking of Racquel Welch and the antibodies in the movie version of Isaac Asimov's Fantastic Voyage...is that completely out-of-date and known to be inaccurate?)

Or is it that once the active site is identified, the invading virion is tagged with chemical markers which call on various leukocytes to engulf it?

Secondary question, woof. If this thing kills by cytokine storm...wouldn't you have a race condition (as they say in the computer world) between the immune response based on the vaccine, to kill the virus particles, and the cytokine storm engendered by (is it the presence of the invading viruses, or the poor lung epithelial cells they've speared, crying for help, which causes the storm) ?

And then maybe there's the idea, that with the long latency between infection and the cytokine storm, maybe that'd give the vaccine-mediated immune response time to kill off the viruses before it reaches the deeper lung tissues to cause the cytokine storm?

...but yes, independent of my flailing, I agree with your assessment.

(And how much can the spike mutate and still attack the lungs, but be mutated enough that the vaccine is useless? Also, IIRC, rheumatic fever leads the immune system to attack the heart muscle. Are there any body tissues whose cellular surface proteins resemble the spike?)

[Black Agnes]

https://thepigsite.com/disease-guide/transmissible-gastro-enteritis-tge-coronavirus-prcv

a related virus.

i’m wondering if some of the swine disease might have been something similar and then it jumped to people. No, I haven’t looked at any sequence similarity.

[boxlunch]

Ok, thanks for that info.

[campaignPete R-CT]

I got the flu shot today. Don’t wanna get deathly ill.

Asked for the Prevnar13 pneumonia shot, but was refused. not in a recommended group,& not 65. Gotta ask my MD.

[Paul R.]

warm, humid climates are ideal for Coronavirus

Wrong.

If a respiratory virus is not in living tissue, infectiousness decreases with increasing time, temperature, surface porosity, and humidity. They don't even do vary well on your hands and have to get transferred to a mucous membrane or such quickly to be infectious.