Posted on 10/28/2019 3:54:31 PM PDT by SunkenCiv
People who take all of their blood-pressure medication in one go at bedtime are better able to control their condition and have “a significantly lower risk of death or illness” caused by heart or blood vessel problems compared to those who take their anti-hypertensive medication in the morning, according to research published this month in the peer-reviewed European Heart Journal.
The trial instructed 19,084 patients to take their pills on waking or at bedtime, and followed them for more than six years — during which time the patients’ ambulatory blood pressure was checked over 48 hours at least once a year. The results were adjusted for age, gender, Type 2 diabetes, kidney disease, smoking and cholesterol levels.
The researchers found that patients who took their medication at bedtime reduced by 45% their risk of dying from or suffering heart attacks, myocardial infarction, stroke, heart failure or requiring a procedure to unblock narrowed arteries, compared to those who took their medication after waking up in the morning.
The risk of death from heart or blood vessel problems was reduced by 66%, the risk of myocardial infarction was reduced by 44%, coronary revascularization (unblocking narrowed arteries) by 40%, heart failure by 42%, and stroke by 49%. However, the researchers noted there are no studies showing that treating hypertension in the morning reduces the risk of cardiovascular disease.
(Excerpt) Read more at marketwatch.com ...
The testosterone tip is a great one, imho, my doc had me on the gel (I was never sure if I enjoyed it or not) but the second time around my insurance wouldn’t cover it. I may start up with the injections. For those who want to try the pills for amorous activities, there’s a TCM herbal called Horny Goat Weed, best results taken in the mid- to late afternoon, assuming happy fun time starts near bedtime.
That sounds like some kind of deep state trick to get me to exercise!!! /jk
Are you on a CPAP machine? Since I've started that, my sleep has been vastly improved, as has the decline in the need to pee every couple hours in the night. Sleep apnea is (surprise to me) related to the development of heart problems including CHF.
What’s CPAP?
“Horny Goat Weed”
There sure are a lot of varieties of weed nowadays. My neighbor smokes one called “Acapulco Gold” and I remember “Maui Wowie” also.
It's a small machine with a hose and mask, used to make sure your breathing doesn't stop at night. First it has to be diagnosed, that requires wearing an electronic gizmo (usually at home, can also be done in their lab for more money) during normal sleep times. My results showed my breathing stopped 70 times an hour, which is only good if I were trying to confuse assassins who use pillows to smother their victims.
Heh... rainy day women #12 & 35.
Partin and Pushkin have presented a case of a 66-year-old man with a history of cardiovascular disease who, after two weeks of consumption of herbal sexual enhancer containing horny goat weed, was admitted to hospital with a new-onset tachyarrhythmia and hypomanic symptoms (sexual and verbal inappropriate behaviour, irritable mood, and hyperverbal speech). The patient needed to undergo an electric cardioversion and to be treated with a therapy based on olanzapine and lorazepam [70].
BTW, the Horny Goat Weed starts to work after a few days or perhaps a bit more of taking it once a day.
Was starting to have blood pressure readings in the “pre-hypertensive” range. In the last few months reduced carbs even more and increased protein (started eating a lot more meat), not paying any attention to fat. Latest reading 114/76.
thanks very much for the ping.
I love that one, “pre-hypertensive” -- it's like saying, "you were almost late" which is of course, "on time". I first noticed its use to refer to 120/80 readings in my parents (they also tended toward low BP, that's where I get it).
Most people have a BP rise in the morning, which might cause the higher incidence of cardiac events in the morning.
Mine rises in the evening, so I time my meds for peak concentration then. Individual variation.
The effect of timing in this study is astonishingly high. I’d like to see it replicated.
Nice!
A symbiotic relationship has been found between diuretics (such as HCTZ) and ACE inhibitors (such as Lisinopril). Each have their own contribution to lowering blood pressure, but when taken together, it is much greater than the sum of the components. Researchers do not yet understand how the combination works, they just know that it does.
You’re right; that’s probably not a good term. To clarify, my systolic was sometimes in the upper 130’s and FWIW has reduced quite significantly after I followed more of a carnivore diet.
Exercise causes the blood vessels to dilate.
So do certain foods like beets which causes an increase in nitric oxide in the bloodstream.
Supplements such as l-arginine, and amino acid, causes an increase in nitric oxide.
Not only is nitric oxide a vasodilator, it is also an ammonia scavenger.
I use a container with seven columns (Sun to Sat) and four rows (Breakfast, Lunch, Dinner, Bedtime). I take my BP, cholesterol, B12, and aspirin at bedtime, so I use the container as a 28 day regimen. I reload it every 28 days. No missed or doubled doses, no opening individual pill bottles, no confusion (did I take my meds already).
That system works real well for me.
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